Výsledky vyhledávání - "Chandra, Sharat H"

Isolation and analysis of sequences showing sex-specific cytosine methylation in the mealybug Planococcus lilacinus

Publikováno v: IndraStra Global.

Genomic libraries of Planococcus lilacinus, a mealybug in which paternal chromosomes are facultatively heterochromatic and inactive in sons but not in daughters, were probed with subtraction probes in order to estimate the number of sequences display

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=issn23813652::c89de7614006877a7be957e0303dc442
http://eprints.iisc.ac.in/17199/1/fulltext.pdf

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The inactive X chromosome in the human female is enriched in 5-methylcytosine to an unusual degree and appears to contain more of this modified nucleotide than the remainder of the genome

Autor: Deobagkar, Deepti D, Chandra, Sharat H

By employing a procedure that combines ELISA and photoacoustic spectroscopy, we have examined the content of 5-methylcytosine (m(5)C) in DNA of individuals who differed from one another in the number of X chromosomes in their genomes. The results sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f53c4b22bbb41c08c549cfec9a1a495b
http://eprints.iisc.ernet.in/40271/

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Characterization of the genome of the mealybug Planococcus lilacinus, a model organism for studying whole-chromosome imprinting and inactivation

Autor: Mohan, Naga K, Ray, Paramita, Chandra, Sharat H

Publikováno v: IndraStra Global.

The co-occurrence of three chromosome-wide phenomena – imprinting, facultative heterochromatization and diffuse centromere – in the mealybug Planococcus lilacinus makes investigation of the genomics of this species an attractive prospect. In orde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=issn23813652::01cfcee304ccba2676e0ed5a502f7f87
http://eprints.iisc.ac.in/12625/1/pradeep_16.pdf

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Requirement of flex (female lethal on X) in the development of the female germ line of Drosophila melanogaster

Autor: Bhattacharya, Ananya, Sudha, S, Balakrishna, Swathi, Chandra, Sharat H

Publikováno v: IndraStra Global.

Drosophila melanogaster females homozygous for flex, an X- linked recessive mutation, do not survive. Hemizygous males are unaffected. Homozygous embryos appear to lack SXL, the product of the Sex-lethal (Sxl) gene, apparently as a result of disrupti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::600a6335577b12d3e04576c27033d792
https://igi.indrastra.com/items/show/188887

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A novel mutation 5' to the HMG box of the SRY gene in a case of Swyer syndrome

Autor: Saifi, Mustafa G, Tilak, Preetha, Veitia, Reiner, Thomas, Manorama I, Tharapel, Avirachan, Mcelreavey, Ken, Fellous, Mark, Chandra, Sharat H

Publikováno v: IndraStra Global.

We describe a novel mutation in the coding region of the SRY gene in a 46,XY female with Swyer syndrome. Analysis of SRY was carried out by direct sequencing of a 780-bp PCR product that included the SRY open reading frame (ORF). This revealed the pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0974667978e7f388a7019bb6bc613b82
http://eprints.iisc.ac.in/1735/1/mutuation.pdf

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Another way of looking at the enigma of sex determination in Ellobius lutescens

Autor: Chandra, Sharat H

A number of hypotheses have been proposed over the years to account for sex determination in the vole Ellobius lutescens (Arvicolinae, Rodentia, Mammalia) (reviewed in ref. 2). The chromosomes of the males of this species are identical to those of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::951eb6ac3b12d3ce0b90c0770d70fdf5
http://eprints.iisc.ernet.in/1559/

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Synergistic interaction between particular X-chromosome deletions andSex-lethal causes female lethality inDrosophila melanogaster

Autor: Anand, Anuranjan, Chandra, Sharat H

Publikováno v: IndraStra Global.

We studied the effect on female viability of trans-heterozygous combinations of X-chromosome deficiencies and Sxt-(fl), a null allele of Sex-lethal. Twentyfive deficiencies, which together covered 80% of the X chromosome, were tested. Seven of these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::31c0f6366522fde369f3f7326efc507c
http://eprints.iisc.ac.in/36849/1/Synergistic_interaction.pdf

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Proposed role of w chromosome inactivation and the absence of dosage compensation in avian sex determination

Autor: Chandra, Sharat H

Publikováno v: IndraStra Global.

Three features of avian sex chromosomes - female heterogamety (ZZ male, ZW female), the apparently inactive state of the W chromosome, and dose-dependent expression of Z-linked genes - are examined in regard to their possible relation to sex determin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=issn23813652::767826f0bbb9c3ed1f367639b1db8c9f
http://eprints.iisc.ac.in/36709/1/proposed_role_of_w.pdf

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How do heterogametic females survive without gene dosage compensation?

Autor: Chandra, Sharat H

When the male is the heterogametic sex (XX♀-XY♂ or XX♀-XO♂), as inDrosophila, orthopteran insects, mammals andCaenorhabditis elegans, X-linked genes are subject to dosage compensation: the single X in the male is functionally equivalent to th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7804694c857b8224611b35f2a3ceca4f
http://eprints.iisc.ernet.in/33870/

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