Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Chandni S. Thakkar"'
Autor:
Asit Ranjan Ghosh, Vijayaparthasarathi Vijayakumar, Asha Kulkarni-Almeida, Vinayak R. Naik, Rajendra R. Kshirsagar, Chandni S. Thakkar, Arvind Saklani
Publikováno v:
Fitoterapia. 114:26-33
In an attempt to discover new scaffolds for anti-diabetic activity from plants, we screened extracts from Ixora brachiata Roxb. for their effect on glucose uptake in L6 myotubes. The petroleum (PE) extract of the plant showed a significant increase i
Autor:
Asit Ranjan Ghosh, Asha Kulkarni-Almeida, Abhijeet S. Kate, Dattatraya C. Desai, Chandni S. Thakkar
Publikováno v:
European Journal of Pharmacology. 769:117-126
NFAT-133 is an aromatic compound with cinammyl alcohol moiety, isolated from streptomycetes strain PM0324667. We have earlier reported that NFAT-133 increases insulin stimulated glucose uptake in L6 myotubes using a PPARγ independent mechanism and r
Autor:
Amrutha Nair, Madhavi Agrawal, Tushar R. Mahajan, Sonali Moghe, Vaishali Deka, Ram A. Vishwakarma, Prashant S. Kharkar, Julie Bose, Chandni S. Thakkar, Asha Kulkarni-Almeida, Dilip Bhedi, Chirag Mehta
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(20)
With the aim to discover orally active small molecules that stimulate glucose uptake, high throughput screening of a library of 5000 drug-like compounds was conducted in differentiated skeletal muscle cells in presence of insulin. N -Substituted phth
Autor:
Lalit S. Doshi, Anagha Damre, Chandni S. Thakkar, Asha Kulkarni-Almeida, Prabhu Padmanabhan, Nitin J. Deshmukh, Umakant Ashok Bahirat, Manoja K. Brahma, Saji George, Kumar V.S. Nemmani, Prabhu Dutt Mishra, Amrutha Nair, Ram A. Vishwakarma, Amol Dixit, Rajashri R. Parab, Pradipta Tokdar, Girish B Mahajan, Nitin V Gaikwad, Prafull Ranadive
Publikováno v:
AMB Express
Type-2 diabetes is mediated by defects in either insulin secretion or insulin action. In an effort to identify extracts that may stimulate glucose uptake, similar to insulin, a high throughput-screening assay for measuring glucose uptake in skeletal