Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Chandeshwar Sharma"'
Autor:
Priscilla F McAuliffe, Kurt W Evans, Argun Akcakanat, Ken Chen, Xiaofeng Zheng, Hao Zhao, Agda Karina Eterovic, Takafumi Sangai, Ashley M Holder, Chandeshwar Sharma, Huiqin Chen, Kim-Anh Do, Emily Tarco, Mihai Gagea, Katherine A Naff, Aysegul Sahin, Asha S Multani, Dalliah M Black, Elizabeth A Mittendorf, Isabelle Bedrosian, Gordon B Mills, Ana Maria Gonzalez-Angulo, Funda Meric-Bernstam
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151121 (2016)
Externí odkaz:
https://doaj.org/article/3f58caf117d4453f9c614ffcebd247ec
Autor:
Priscilla F McAuliffe, Kurt W Evans, Argun Akcakanat, Ken Chen, Xiaofeng Zheng, Hao Zhao, Agda Karina Eterovic, Takafumi Sangai, Ashley M Holder, Chandeshwar Sharma, Huiqin Chen, Kim-Anh Do, Emily Tarco, Mihai Gagea, Katherine A Naff, Aysegul Sahin, Asha S Multani, Dalliah M Black, Elizabeth A Mittendorf, Isabelle Bedrosian, Gordon B Mills, Ana Maria Gonzalez-Angulo, Funda Meric-Bernstam
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136851 (2015)
Breast cancer patients who are resistant to neoadjuvant chemotherapy (NeoCT) have a poor prognosis. There is a pressing need to develop in vivo models of chemo resistant tumors to test novel therapeutics. We hypothesized that patient-derived breast c
Externí odkaz:
https://doaj.org/article/7b19cd5ca69e48e9bcf7d70a6c6b420b
Autor:
Ken Chen, Funda Meric-Bernstam, Kim Anh Do, Ashley M. Holder, Mihai Gagea, Chandeshwar Sharma, Katherine A. Naff, Emily Tarco, Elizabeth A. Mittendorf, Takafumi Sangai, Hao Zhao, Xiaofeng Zheng, Kurt W. Evans, Agda Karina Eterovic, Argun Akcakanat, Aysegul Sahin, Isabelle Bedrosian, Huiqin Chen, Priscilla F. McAuliffe, Gordon B. Mills, Asha S. Multani, Dalliah M. Black, Ana M. Gonzalez-Angulo
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151121 (2016)
Publikováno v:
Growth Factors. 27:12-21
Ribosomal protein S6 kinase 1 (S6K1), a critical mediator of cell growth, is overexpressed in breast cancer and is associated with poor prognosis. S6K1 has two known isoforms, p85(S6K1) and p70(S6K1). p85(S6K1) is characterized by 23 additional amino
Autor:
Elizabeth A. Mittendorf, Kim Anh Do, Argun Akcakanat, Kurt W. Evans, Funda Meric-Bernstam, Dalliah M. Black, Isabelle Bedrosian, Chandeshwar Sharma, Ana M. Gonzalez-Angulo, Mihai Gagea, Xiaofeng Zheng, Emily Tarco, Aysegul A. Sahin, Katherine A. Naff, Ken Chen, Agda Karina Eterovic, Huiqin Chen, Ashley M. Holder, Hao Zhao, Priscilla F. McAuliffe, Gordon B. Mills, Asha S. Multani, Takafumi Sangai
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136851 (2015)
PLoS ONE
PLoS ONE
Background Breast cancer patients who are resistant to neoadjuvant chemotherapy (NeoCT) have a poor prognosis. There is a pressing need to develop in vivo models of chemo resistant tumors to test novel therapeutics. We hypothesized that patient-deriv
Autor:
Funda Meric-Bernstam, Argun Akcakanat, Chandeshwar Sharma, Gopal Singh, A. M. Gonzalez-Angulo, Priscilla F. McAuliffe
Publikováno v:
Cancer Research. 70:P1-03
Background: Breast cancer patients who have significant residual cancer after neoadjuvant chemotherapy (NCT) are at high risk of relapse. There is a pressing need to identify novel therapeutics that can be offered to these patients. In vivo models av
Publikováno v:
Chemistry and Physics of Lipids. 104:1-11
Sphingosine inhibits the activity of the skeletal muscle Ca2+ release channel (ryanodine receptor) and is a noncompetitive inhibitor of [3H]ryanodine binding (Needleman et al., Am. J. Physiol. 272, C1465-1474, 1997). To determine the contribution of
Autor:
Kurt W. Evans, Ana M. Gonzalez-Angulo, Hao Zhao, Agda Karina Eterovic, Huiqin Chen, Priscilla F. McAuliffe, Kim Anh Do, Katherine A. Naff, Gordon B. Mills, Argun Akcakanat, Asha S. Multani, William Fraser Symmans, Chandeshwar Sharma, Funda Meric-Bernstam, Ken Chen, Ashley M. Holder, Aysegul A. Sahin, Takafumi Sangai, Mihai Gagea
Publikováno v:
Cancer Research. 74:1186-1186
Introduction: Patients with breast cancer who do not respond to standard systemic therapy have a poor prognosis. There is a pressing need to develop in vivo models of breast cancer to test novel therapeutics. Directly implanting tumors into immunodef
Autor:
Argun Akcakanat, Katherine A. Naff, Chandeshwar Sharma, Gopal Singh, Funda Meric-Bernstam, David Luyimbazi
Publikováno v:
Nutrition and cancer. 63(2)
The mammalian target of rapamycin (mTOR) is a central controller of cell growth and is currently being investigated as a potential target in breast cancer therapy. The essential amino acid leucine has been proposed to regulate mTOR signaling. The obj
Autor:
Priscilla F. McAuliffe, Gordon B. Mills, Chandeshwar Sharma, Kim Anh Do, Katherine S. Hale, Huiqin Chen, W. Fraser Symmans, A. M. Gonzalez-Angulo, Argun Akcakanat, Funda Meric-Bernstam
Publikováno v:
Journal of the American College of Surgeons. 213:S28
INTRODUCTION: Directly implanting human tumors into immunodeficient mice is a popular model as it may more accurately recapitulate tumor characteristics. Prognosis is poor for breast cancer patients with minimal response to neoadjuvant chemotherapy (