Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Chandani Limbad"'
Autor:
Chandani Limbad, Ryosuke Doi, Julia McGirr, Serban Ciotlos, Kevin Perez, Zachary S. Clayton, Radha Daya, Douglas R. Seals, Judith Campisi, Simon Melov
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103848- (2022)
Summary: Cellular senescence is a driver of many age-related pathologies. There is an active search for pharmaceuticals termed senolytics that can mitigate or remove senescent cells in vivo by targeting genes that promote the survival of senescent ce
Externí odkaz:
https://doaj.org/article/14bce5cea8b64b049e1f8d6343cdc4ed
Autor:
Chandani Limbad, Tal Ronnen Oron, Fatouma Alimirah, Albert R Davalos, Tara E Tracy, Li Gan, Pierre-Yves Desprez, Judith Campisi
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227887 (2020)
Neurodegeneration is a major age-related pathology. Cognitive decline is characteristic of patients with Alzheimer's and related dementias and cancer patients after chemo- or radio-therapies. A recently emerged driver of these and other age-related p
Externí odkaz:
https://doaj.org/article/6d1b037837964e13b4012a4b77ba6628
Autor:
Shankar J. Chinta, Georgia Woods, Marco Demaria, Anand Rane, Ying Zou, Amanda McQuade, Subramanian Rajagopalan, Chandani Limbad, David T. Madden, Judith Campisi, Julie K. Andersen
Publikováno v:
Cell Reports, Vol 22, Iss 4, Pp 930-940 (2018)
Exposure to the herbicide paraquat (PQ) is associated with an increased risk of idiopathic Parkinson’s disease (PD). Therapies based on PQ’s presumed mechanisms of action have not, however, yielded effective disease therapies. Cellular senescence
Externí odkaz:
https://doaj.org/article/a50111f1811844c78146b1804f884ac5
Autor:
Christopher D. Wiley, Su Liu, Chandani Limbad, Anna M. Zawadzka, Jennifer Beck, Marco Demaria, Robert Artwood, Fatouma Alimirah, Jose-Alberto Lopez-Dominguez, Chisaka Kuehnemann, Steven R. Danielson, Natan Basisty, Herbert G. Kasler, Tal Ronnen Oron, Pierre-Yves Desprez, Sean D. Mooney, Bradford W. Gibson, Birgit Schilling, Judith Campisi, Pankaj Kapahi
Publikováno v:
Cell Reports, Vol 28, Iss 13, Pp 3329-3337.e5 (2019)
Summary: Cellular senescence irreversibly arrests cell proliferation, accompanied by a multi-component senescence-associated secretory phenotype (SASP) that participates in several age-related diseases. Using stable isotope labeling with amino acids
Externí odkaz:
https://doaj.org/article/18d57d9f49ba45cebd45a0fa32ce2405
Autor:
Sean D. McAllister, Pierre-Yves Desprez, Garret L. Yount, Dan H. Moore, Chandani Limbad, Juanita Allison, Arash Pakdel, Jasmine Lee, Maxx P. Horowitz, Anne J. Zielinski, Darryl Lau, Rigel T. Christian, Jahan P. Marcu
Supplementary Figure 1 from Cannabidiol Enhances the Inhibitory Effects of Δ9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d2feabcdd57f1d4d0af302f3782c7a
https://doi.org/10.1158/1535-7163.22484864
https://doi.org/10.1158/1535-7163.22484864
Autor:
Sean D. McAllister, Pierre-Yves Desprez, Garret L. Yount, Dan H. Moore, Chandani Limbad, Juanita Allison, Arash Pakdel, Jasmine Lee, Maxx P. Horowitz, Anne J. Zielinski, Darryl Lau, Rigel T. Christian, Jahan P. Marcu
Supplementary Figure 2 from Cannabidiol Enhances the Inhibitory Effects of Δ9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a1fbeab08858f1c7542720339d909d
https://doi.org/10.1158/1535-7163.22484861
https://doi.org/10.1158/1535-7163.22484861
Autor:
Judith Campisi, Pierre-Yves Desprez, Chandani Limbad, Christopher D. Wiley, Albert R. Davalos, Marco Demaria, Michael C. Velarde, Jose Flores, Diego A. Diaz, Elijah Jones, Emily Chang, Sena Alptekin, Alexis Valdovinos, Tanya Pulido, Fatouma Alimirah
Supplementary Data supporting the manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59381d521715fc65caf131847259a20
https://doi.org/10.1158/0008-5472.22425504
https://doi.org/10.1158/0008-5472.22425504
Autor:
Sean D. McAllister, Pierre-Yves Desprez, Garret L. Yount, Dan H. Moore, Chandani Limbad, Juanita Allison, Arash Pakdel, Jasmine Lee, Maxx P. Horowitz, Anne J. Zielinski, Darryl Lau, Rigel T. Christian, Jahan P. Marcu
The cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptor agonist Δ9-tetrahydrocannabinol (THC) has been shown to be a broad-range inhibitor of cancer in culture and in vivo, and is currently being used in a clinical trial for the treatment of gliobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a3a80d918daf9144f0d27da2167a95
https://doi.org/10.1158/1535-7163.c.6531623
https://doi.org/10.1158/1535-7163.c.6531623
Autor:
Judith Campisi, Pierre-Yves Desprez, Chandani Limbad, Christopher D. Wiley, Albert R. Davalos, Marco Demaria, Michael C. Velarde, Jose Flores, Diego A. Diaz, Elijah Jones, Emily Chang, Sena Alptekin, Alexis Valdovinos, Tanya Pulido, Fatouma Alimirah
Cellular senescence entails an irreversible growth arrest that evolved in part to prevent cancer. Paradoxically, senescent cells secrete proinflammatory and growth-stimulatory molecules, termed the senescence-associated secretory phenotype (SASP), wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cbf005205af3a3a2da05c292515bfa6
https://doi.org/10.1158/0008-5472.c.6512058.v1
https://doi.org/10.1158/0008-5472.c.6512058.v1
Autor:
Sean D. McAllister, Pierre-Yves Desprez, Garret L. Yount, Dan H. Moore, Chandani Limbad, Juanita Allison, Arash Pakdel, Jasmine Lee, Maxx P. Horowitz, Anne J. Zielinski, Darryl Lau, Rigel T. Christian, Jahan P. Marcu
Supplementary Table 1, Figure Legends 1-2 from Cannabidiol Enhances the Inhibitory Effects of Δ9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6cbd697f599c63050635d0a7f61133
https://doi.org/10.1158/1535-7163.22484858
https://doi.org/10.1158/1535-7163.22484858