Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Chandani K. Hennayake"'
Autor:
Vishal Musale, Colin E. Murdoch, Ayman K. Banah, Annie Hasib, Chandani K. Hennayake, Bo Dong, Chim C. Lang, David H. Wasserman, Li Kang
Publikováno v:
Molecular Metabolism, Vol 86, Iss , Pp 101970- (2024)
Objective: Obesity increases deposition of extracellular matrix (ECM) components of cardiac tissue. Since obesity aggregates with insulin resistance and heart disease, it is imperative to determine whether the increased ECM deposition contributes to
Externí odkaz:
https://doaj.org/article/a263f7a9365d413da8217d61d8a513a5
Autor:
Aimée R. Bugler-Lamb, Annie Hasib, Xiong Weng, Chandani K. Hennayake, Chenshi Lin, Rory J. McCrimmon, Roland H. Stimson, Michael L.J. Ashford, David H. Wasserman, Li Kang
Publikováno v:
Molecular Metabolism, Vol 49, Iss , Pp 101197- (2021)
Objective: Increased deposition of the extracellular matrix (ECM) in adipose tissue (AT) during obesity contributes to insulin resistance. The integrin receptors transmit changes in the extracellular environment causing corresponding intracellular ad
Externí odkaz:
https://doaj.org/article/ceb76794140e453f96fb9d477902bccb
Autor:
Faisel Khan, Annie Hasib, Li Kang, Chandani K. Hennayake, David H. Wasserman, Michael L.J. Ashford, Aimée R. Bugler-Lamb, Louise Lantier, Deanna P. Bracy, Rory J. McCrimmon
Publikováno v:
Am J Physiol Endocrinol Metab
Extracellular matrix hyaluronan is increased in skeletal muscle of high-fat-fed insulin-resistant mice, and reduction of hyaluronan by PEGPH20 hyaluronidase ameliorates diet-induced insulin resistance (IR). CD44, the main hyaluronan receptor, is posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba8042f1e7ddc2590c1e43f15d1c55b
https://doi.org/10.1152/ajpendo.00215.2019
https://doi.org/10.1152/ajpendo.00215.2019
Autor:
Li Kang, Rory J. McCrimmon, Chandani K. Hennayake, Chenshi Lin, David H. Wasserman, Michael L.J. Ashford, Annie Hasib, Aimée R. Bugler-Lamb, Xiong Weng, Roland H Stimson
Publikováno v:
Bugler-Lamb, A R, Hasib, A, Weng, X, Hennayake, C K, Lin, C, McCrimmon, R J, Stimson, R H, Ashford, M L J, Wasserman, D H & Kang, L 2021, ' Adipocyte Integrin-Linked Kinase Plays a Key Role in the Development of Diet-Induced Adipose Insulin Resistance in Male Mice ', Molecular Metabolism . https://doi.org/10.1016/j.molmet.2021.101197
Molecular Metabolism
Molecular Metabolism, Vol 49, Iss, Pp 101197-(2021)
Molecular Metabolism
Molecular Metabolism, Vol 49, Iss, Pp 101197-(2021)
Objective Increased deposition of the extracellular matrix (ECM) in adipose tissue (AT) during obesity contributes to insulin resistance. The integrin receptors transmit changes in the extracellular environment causing corresponding intracellular ada
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2220c550f1ea5561ee9bcd4e29b8c6a
https://hdl.handle.net/20.500.11820/ac25f46a-e6be-44e7-9b61-148a81efc8d3
https://hdl.handle.net/20.500.11820/ac25f46a-e6be-44e7-9b61-148a81efc8d3
Publikováno v:
Diabetes. 68
The remodeling of the extracellular matrix (ECM) in tissues including adipose tissue, and the expression of collagen binding integrin α2β1 have been associated with the development of insulin resistance. Integrin-linked Kinase (ILK), an adaptor pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33977fcd194afd89751f86658a7ef9cc
https://doi.org/10.2337/db19-270-or
https://doi.org/10.2337/db19-270-or
Autor:
Li Kang, Deanna P. Bracy, Shilpa Mokshagundam, Daniel S. Lark, Claire Sneddon, Freyja D. James, Ambra Pozzi, Bradley Reuter, Roy Zent, David H. Wasserman, Ashley S. Williams, Chandani K. Hennayake
Publikováno v:
Diabetes
Diet-induced muscle insulin resistance is associated with expansion of extracellular matrix (ECM) components, such as collagens, and the expression of collagen-binding integrin, α2β1. Integrins transduce signals from ECM via their cytoplasmic domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794e9bdeb7adc0ffca26755e1615dc3a
https://doi.org/10.2337/db15-1434
https://doi.org/10.2337/db15-1434