Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Chandan, Shee"'
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 714-721 (2012)
Mutation hotspots and showers occur across phylogeny and profoundly influence genome evolution, yet the mechanisms that produce hotspots remain obscure. We report that DNA double-strand breaks (DSBs) provoke mutation hotspots via stress-induced mutat
Externí odkaz:
https://doaj.org/article/2d43bee304b747af94b2fc21863a617d
Autor:
Chandan Shee, Ben D Cox, Franklin Gu, Elizabeth M Luengas, Mohan C Joshi, Li-Ya Chiu, David Magnan, Jennifer A Halliday, Ryan L Frisch, Janet L Gibson, Ralf Bernd Nehring, Huong G Do, Marcos Hernandez, Lei Li, Christophe Herman, PJ Hastings, David Bates, Reuben S Harris, Kyle M Miller, Susan M Rosenberg
Publikováno v:
eLife, Vol 2 (2013)
Spontaneous DNA breaks instigate genomic changes that fuel cancer and evolution, yet direct quantification of double-strand breaks (DSBs) has been limited. Predominant sources of spontaneous DSBs remain elusive. We report synthetic technology for qua
Externí odkaz:
https://doaj.org/article/59c34746bcbd42bfa4a8ac9f9ebfc171
Autor:
Pradeep L. Ramachandran, Elizabeth A. Holmes, Chinmay Pangarkar, Karthik Jayasurya, Jared O'Leary, Chandan Shee, Alphonso Nguyen, Lucie S. Lee, Laura Hyland, Marilyn B. Nourse, Kevin D. Ha, Steven Chow, Samartha Anekal, Pradeep Bhatta, Steven F. Gessert, Ran Hu, Kate Engel, Renuka Shenoy, Yang Lily Liu, Bernardo Sosa-Padilla, Ushati Das, Amy Yuan, Jerald F. Sapida, Joy Roy, Peter Zhao, Lorraine Tran, Dariusz Wodziak, Amanda Trent, Daniel L. Young, Shekar Chandrasekaran, Amy R. Rappaport, Ken Quon, Andrew N. Kim, Yutao Chen, Timothy Michael Kemp, Arvind Jammalamadaka, Thomas C. Waggoner, Jocelyn A. Bailey, Channing R. Robertson, Xinwei Gong, Erez Galil, Nikolay V. Sergeev, Devayani Bhave, Sharada Sivaraman, Paul Patel
Publikováno v:
Bioengineering & Translational Medicine. 3:58-70
The ability to perform laboratory testing near the patient and with smaller blood volumes would benefit patients and physicians alike. We describe our design of a miniaturized clinical laboratory system with three components: a hardware platform (ie,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0daa82ddde3ee9b3c438d0de1df2fdb1
https://doi.org/10.1002/btm2.10084
https://doi.org/10.1002/btm2.10084
Autor:
Marilyn B, Nourse, Kate, Engel, Samartha G, Anekal, Jocelyn A, Bailey, Pradeep, Bhatta, Devayani P, Bhave, Shekar, Chandrasekaran, Yutao, Chen, Steven, Chow, Ushati, Das, Erez, Galil, Xinwei, Gong, Steven F, Gessert, Kevin D, Ha, Ran, Hu, Laura, Hyland, Arvind, Jammalamadaka, Karthik, Jayasurya, Timothy M, Kemp, Andrew N, Kim, Lucie S, Lee, Yang Lily, Liu, Alphonso, Nguyen, Jared, O'Leary, Chinmay H, Pangarkar, Paul J, Patel, Ken, Quon, Pradeep L, Ramachandran, Amy R, Rappaport, Joy, Roy, Jerald F, Sapida, Nikolay V, Sergeev, Chandan, Shee, Renuka, Shenoy, Sharada, Sivaraman, Bernardo, Sosa-Padilla, Lorraine, Tran, Amanda, Trent, Thomas C, Waggoner, Dariusz, Wodziak, Amy, Yuan, Peter, Zhao, Daniel L, Young, Channing R, Robertson, Elizabeth A, Holmes
Publikováno v:
Bioengineering & Translational Medicine
The ability to perform laboratory testing near the patient and with smaller blood volumes would benefit patients and physicians alike. We describe our design of a miniaturized clinical laboratory system with three components: a hardware platform (ie,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e900230d409d74895e57e6e41d7a7c01
https://pubmed.ncbi.nlm.nih.gov/29376134
https://pubmed.ncbi.nlm.nih.gov/29376134
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 714-721 (2012)
Cell Reports
Cell Reports
Summary Mutation hotspots and showers occur across phylogeny and profoundly influence genome evolution, yet the mechanisms that produce hotspots remain obscure. We report that DNA double-strand breaks (DSBs) provoke mutation hotspots via stress-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d09a2d24c82d5495d20c9bb0aa7549
Autor:
Girijesh Kumar Patel, Deepankar Gahloth, Chandan Shee, Ashwani Sharma, Purushotham Selvakumar
Publikováno v:
Medicinal Chemistry Research. 20:1542-1549
The Murraya koenigii miraculin-like protein (MKMLP) has been shown to have unusual solubility and stability properties. Here, the conformational stability and the solubility of MKMLP were assessed in different physicochemical conditions. In solubilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56d82ed996cb3f53c4d2e6b1862ea11a
https://doi.org/10.1007/s00044-010-9404-4
https://doi.org/10.1007/s00044-010-9404-4
Publikováno v:
Journal of Plant Biochemistry and Biotechnology. 18:101-104
A low molecular mass peptide like compound with antimicrobial and trypsin inhibitory activity was isolated from the seeds of Lagenaria siceraria. It was purified by ion-exchange and reverse-phase chromatography. The molecular weight of the compound w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6edb9cd811222ea70b0f9ac8c0c32b73
https://doi.org/10.1007/bf03263304
https://doi.org/10.1007/bf03263304
Autor:
Pravindra Kumar, Dinesh Yernool, Ashwani Sharma, Asimul Islam, Chandan Shee, Navneet S. Chaudhary, Faizan Ahmad
Publikováno v:
Phytochemistry. 69:2120-2126
A highly stable and potent trypsin inhibitor was purified to homogeneity from the seeds of Putranjiva roxburghii belonging to Euphorbiaceae family by acid precipitation, cation-exchange and anion-exchange chromatography. SDS-PAGE analysis, under redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d380392eb7cff8a05f34f0633c49165
https://doi.org/10.1016/j.phytochem.2008.05.002
https://doi.org/10.1016/j.phytochem.2008.05.002
Autor:
Ashwani Sharma, Chandan Shee
Publikováno v:
Food Chemistry. 107:312-319
The Murraya Koenigii trypsin inhibitor was found to be the major protein component of the seed extract. The quantity of protein was determined to be approximately 20% of total protein extracted by simple buffer extraction. During different stages of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91f99bde9d08ab0ae79363033a7e8592
https://doi.org/10.1016/j.foodchem.2007.08.020
https://doi.org/10.1016/j.foodchem.2007.08.020
Publikováno v:
International Journal of Biological Macromolecules. 41:410-414
Structure-function studies of Murraya koenigii trypsin inhibitor revealed a compact structure made of central beta-sheet surrounded by alpha-helices with differences in structure and functional stability. Proteolysis studies, of native and heat-treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560374935ee1be5c90b9398b3154a93e
https://doi.org/10.1016/j.ijbiomac.2007.05.011
https://doi.org/10.1016/j.ijbiomac.2007.05.011