Distinct tumor architectures and microenvironments for the initiation of breast cancer metastasis in the brain

Autor: Gan, Siting, Macalinao, Danilo G., Shahoei, Sayyed Hamed, Tian, Lin, Jin, Xin, Basnet, Harihar, Bibby, Catherine, Muller, James T., Atri, Pranita, Seffar, Evan, Chatila, Walid, Karacay, Ali, Chanda, Pharto, Hadjantonakis, Anna-Katerina, Schultz, Nikolaus, Brogi, Edi, Bale, Tejus A., Moss, Nelson S., Murali, Rajmohan, Pe’er, Dana, Massagué, Joan

Publikováno v: In Cancer Cell 14 October 2024 42(10):1693-1712

Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms.

Autor: Sun S; Halvorsen Center for Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: suns3@mskcc.org., You E; Massachusetts General Cancer Center, Harvard Medical School, Charlestown, MA, USA., Hong J; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hoyos D; Tri-Institutional Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY, USA., Del Priore IS; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Tsanov KM; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Mattagajasingh O; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montreal, QC, Canada., Di Gioacchino A; Laboratoire de Physique de l'Ecole Normale Supérieure, Sorbonne Université, Université de Paris, Paris, France., Marhon SA; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Chacon-Barahona J; Tri-Institutional Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY, USA., Li H; Halvorsen Center for Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Jiang H; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY, USA., Hozeifi S; European Research Institute for the Biology of Ageing, University Medical Center Groningen, Groningen, The Netherlands., Rosas-Bringas O; European Research Institute for the Biology of Ageing, University Medical Center Groningen, Groningen, The Netherlands., Xu KH; Massachusetts General Cancer Center, Harvard Medical School, Charlestown, MA, USA., Song Y; Massachusetts General Cancer Center, Harvard Medical School, Charlestown, MA, USA., Lang ER; Massachusetts General Cancer Center, Harvard Medical School, Charlestown, MA, USA., Rojas AS; Massachusetts General Cancer Center, Harvard Medical School, Charlestown, MA, USA., Nieman LT; Massachusetts General Cancer Center, Harvard Medical School, Charlestown, MA, USA., Patel BK; Massachusetts General Cancer Center, Harvard Medical School, Charlestown, MA, USA., Murali R; Last Wish Program and Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chanda P; Last Wish Program and Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Karacay A; Last Wish Program and Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Vabret N; Precision Immunology Institute at the Icahn School of Medicine at Mount Sinai, New York, NY, USA., De Carvalho DD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Zenklusen D; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montreal, QC, Canada., LaCava J; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, NY, USA., Lowe SW; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Ting DT; Massachusetts General Cancer Center, Harvard Medical School, Charlestown, MA, USA., Iacobuzio-Donahue CA; David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Last Wish Program and Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Solovyov A; Halvorsen Center for Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Greenbaum BD; Halvorsen Center for Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Physiology, Biophysics & Systems Biology, Weill Cornell Medicine, New York, NY, USA. Electronic address: greenbab@mskcc.org.

Publikováno v: Immunity [Immunity] 2024 Nov 20. Date of Electronic Publication: 2024 Nov 20.