Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Chance M Nowak"'
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 6, p e1011080 (2023)
The cell cycle consists of a series of orchestrated events controlled by molecular sensing and feedback networks that ultimately drive the duplication of total DNA and the subsequent division of a single parent cell into two daughter cells. The abili
Externí odkaz:
https://doaj.org/article/f5f87f625a864d0d9352359fd3ed4a78
Publikováno v:
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Herein, we implement and access machine learning architectures to ascertain models that differentiate healthy from apoptotic cells using exclusively forward (FSC) and side (SSC) scatter flow cytometry information. To generate training data,
Externí odkaz:
https://doaj.org/article/f1e3a60d60654b6bbac2e007e799a270
Autor:
Taek Kang, Tyler Quarton, Chance M. Nowak, Kristina Ehrhardt, Abhyudai Singh, Yi Li, Leonidas Bleris
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101595- (2020)
Summary: MicroRNAs (miRNAs) are short non-coding RNA molecules that regulate gene expression post-transcriptionally by binding to target messenger RNAs (mRNAs). Many human miRNAs are intragenic, located within introns of protein-coding sequence (host
Externí odkaz:
https://doaj.org/article/775afe91b80947e0937de679290e8f24
Publikováno v:
Science Advances. 8
A physical unclonable function (PUF) is a physical entity that provides a measurable output that can be used as a unique and irreproducible identifier for the artifact wherein it is embedded. Popularized by the electronics industry, silicon PUFs leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9041a5b74056a78939b655dc26dc739
https://doi.org/10.1126/sciadv.abm4106
https://doi.org/10.1126/sciadv.abm4106
The cell cycle consists of a series of orchestrated events controlled by molecular sensing and feedback networks that ultimately drive the duplication of total DNA and the subsequent division of a single parent cell into two daughter cells. The abili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a344cc1aba3d5c5334e2a7d92e175c61
https://doi.org/10.1101/2021.10.13.464184
https://doi.org/10.1101/2021.10.13.464184
Single-Molecule Detection of SARS-CoV-2 by Plasmonic Sensing of Isothermally Amplified Nucleic Acids
Autor:
Yaning Liu, Haihang Ye, Leonidas Bleris, Chance M. Nowak, Tingting Zhang, Yi Li, Zhenpeng Qin
Publikováno v:
medRxiv
The ability to detect pathogens specifically and sensitively is critical to combat infectious diseases outbreaks and pandemics. Colorimetric assays involving loop-mediated isothermal amplification (LAMP) provide simple readouts yet suffer from the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a839c5b8c19904ed610ff7612f7be6
https://europepmc.org/articles/PMC8509104/
https://europepmc.org/articles/PMC8509104/
Publikováno v:
NPJ Systems Biology and Applications
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-9 (2021)
npj Systems Biology and Applications, Vol 7, Iss 1, Pp 1-9 (2021)
Herein, we implement and access machine learning architectures to ascertain models that differentiate healthy from apoptotic cells using exclusively forward (FSC) and side (SSC) scatter flow cytometry information. To generate training data, colorecta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f1739f673ac14e05b5658871e469a5
https://doi.org/10.1038/s41540-021-00180-y
https://doi.org/10.1038/s41540-021-00180-y
Publikováno v:
SSRN Electronic Journal.
We introduce a novel methodology, namely CRISPR-Engineered Attestation of Mammalian Cells using Physical Unclonable Functions (CREAM-PUFs), which can serve as the cornerstone for formally verifying transactions in human cell line distribution network
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10219ddaa85f69b04697e2326eca2233
https://doi.org/10.2139/ssrn.3887803
https://doi.org/10.2139/ssrn.3887803
Autor:
Chance M. Nowak, Taek Kang, Abhyudai Singh, Leonidas Bleris, Kristina Ehrhardt, Yi Li, Tyler Quarton
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101595-(2020)
iScience
iScience
Summary MicroRNAs (miRNAs) are short non-coding RNA molecules that regulate gene expression post-transcriptionally by binding to target messenger RNAs (mRNAs). Many human miRNAs are intragenic, located within introns of protein-coding sequence (host)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad8d801e351eb9db1ff646bbf1018f0
http://www.sciencedirect.com/science/article/pii/S2589004220307872
http://www.sciencedirect.com/science/article/pii/S2589004220307872
Autor:
Chance M. Nowak, Zhuo Chen, Hamilton Lee, Candace E. Benjamin, Raymond P. Welch, Sheena D'Arcy, Madushani Dharmarwardana, Kyle W. Murray, Leonidas Bleris, Jeremiah J. Gassensmith, Lana H. Tuong
Publikováno v:
Molecular Pharmaceutics. 15:2984-2990
Controlling the uptake of nanomaterials into phagocytes is a challenging problem. We describe an approach to inhibit the cellular uptake by macrophages and HeLa cells of nanoparticles derived from bacteriophage Qβ by conjugating negatively charged t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92228810d05b06957a9b2193bd32eb96
https://doi.org/10.1021/acs.molpharmaceut.8b00348
https://doi.org/10.1021/acs.molpharmaceut.8b00348