Integrating contact tracing and whole-genome sequencing to track the elimination of dog-mediated rabies: An observational and genomic study

Autor: Kennedy Lushasi, Kirstyn Brunker, Malavika Rajeev, Elaine A Ferguson, Gurdeep Jaswant, Laurie Louise Baker, Roman Biek, Joel Changalucha, Sarah Cleaveland, Anna Czupryna, Anthony R Fooks, Nicodemus J Govella, Daniel T Haydon, Paul CD Johnson, Rudovick Kazwala, Tiziana Lembo, Denise Marston, Msanif Masoud, Matthew Maziku, Eberhard Mbunda, Geofrey Mchau, Ally Z Mohamed, Emmanuel Mpolya, Chanasa Ngeleja, Kija Ng'habi, Hezron Nonga, Kassim Omar, Kristyna Rysava, Maganga Sambo, Lwitiko Sikana, Rachel Steenson, Katie Hampson

Publikováno v: eLife, Vol 12 (2023)

Background: Dog-mediated rabies is endemic across Africa causing thousands of human deaths annually. A One Health approach to rabies is advocated, comprising emergency post-exposure vaccination of bite victims and mass dog vaccination to break the tr

Externí odkaz: https://doaj.org/article/b5ad4c20170644f197eabda3df455151

Rapid in-country sequencing of whole virus genomes to inform rabies elimination programmes [version 1; peer review: 2 approved]

Autor: Kirstyn Brunker, Gurdeep Jaswant, S.M. Thumbi, Kennedy Lushasi, Ahmed Lugelo, Anna M. Czupryna, Fred Ade, Gati Wambura, Veronicah Chuchu, Rachel Steenson, Chanasa Ngeleja, Criselda Bautista, Daria L. Manalo, Ma. Ricci R. Gomez, Maria Yna Joyce V. Chu, Mary Elizabeth Miranda, Maya Kamat, Kristyna Rysava, Jason Espineda, Eva Angelica V. Silo, Ariane Mae Aringo, Rona P. Bernales, Florencio F. Adonay, Michael J. Tildesley, Denise A. Marston, Daisy L. Jennings, Anthony R. Fooks, Wenlong Zhu, Luke W. Meredith, Sarah C. Hill, Radoslaw Poplawski, Robert J. Gifford, Joshua B. Singer, Mathew Maturi, Athman Mwatondo, Roman Biek, Katie Hampson

Publikováno v: Wellcome Open Research, Vol 5 (2020)

Genomic surveillance is an important aspect of contemporary disease management but has yet to be used routinely to monitor endemic disease transmission and control in low- and middle-income countries. Rabies is an almost invariably fatal viral diseas

Externí odkaz: https://doaj.org/article/a2af14cb359c4b6b8ecac9f516e1e97a

Integrating contact tracing and whole-genome sequencing to track the elimination of dog-mediated rabies

Autor: Kennedy Lushasi, Kirstyn Brunker, Malavika Rajeev, Elaine A Ferguson, Gurdeep Jaswant, Laurie Baker, Roman Biek, Joel Changalucha, Sarah Cleaveland, Anna Czupryna, Anthony R Fooks, Nicodemus Govella, Daniel T Haydon, Paul Johnson, Rudovick Kazwala, Tiziana Lembo, Denise Marston, Msanif Masoud, Mathew Maziku, Eberhard Mbunda, Geofrey Mchau, Ally Z Mohamed, Emmanuel Mpolya, Chanasa Ngeleja, Kija Ng’abhi, Hesron Nonga, Khasim Omar, Kristyna Rysava, Maganga Sambo, Lwitiko Sikana, Rachel Steenson, Katie Hampson

BackgroundDog-mediated rabies is endemic across Africa causing thousands of human deaths annually. A One Health approach to rabies is advocated, comprising emergency post-exposure vaccination of bite victims and mass dog vaccination to break the tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e2faff34d449c841e093159876b47aa
https://doi.org/10.1101/2022.11.24.22282675

Rapid in-country sequencing of whole virus genomes to inform rabies elimination programmes

Autor: Florencio F Adonay, Rachel Steenson, Kennedy Lushasi, Criselda Bautista, Anthony R. Fooks, Michael J. Tildesley, Kirstyn Brunker, Wenlong Zhu, Jason Espineda, Roman Biek, Ma Ricci R Gomez, Fred Ade, Maya Kamat, Eva Angelica V Silo, Daria L. Manalo, Ahmed Lugelo, Robert J. Gifford, Denise A. Marston, Luke W. Meredith, Mathew Maturi, Ariane Mae Aringo, Rona P Bernales, Joshua B Singer, Athman Mwatondo, Kristyna Rysava, Katie Hampson, Daisy Jennings, Maria Yna Joyce V Chu, Veronicah Chuchu, Mary Elizabeth Miranda, Samuel M. Thumbi, Gurdeep Jaswant, Chanasa Ngeleja, Anna Czupryna, Sarah C. Hill, Gati Wambura, Radoslaw Poplawski

Publikováno v: Brunker, K, Jaswant, G, Thumbi, S M, Lushasi, K, Lugelo, A, Czupryna, A M, Ade, F, Wambura, G, Chuchu, V, Steenson, R, Ngeleja, C, Bautista, C, Manalo, D L, Gomez, M R R, Chu, M Y J V, Miranda, M E, Kamat, M, Rysava, K, Espineda, J, Silo, E A V, Aringo, A M, Bernales, R P, Adonay, F F, Tildesley, M J, Marston, D A, Jennings, D L, Fooks, A R, Zhu, W, Meredith, L W, Poplawski, R, Singer, J B, Maturi, M, Mwatondo, A, Biek, R & Hampson, K 2020, ' Rapid in-country sequencing of whole virus genomes to inform rabies elimination programmes ', Wellcome Open Research, vol. 5, no. 3 . https://doi.org/10.12688/wellcomeopenres.15518.2

Genomic surveillance is an important aspect of contemporary disease management but has yet to be used routinely to monitor endemic disease transmission and control in low- and middle-income countries. Rabies is an almost invariably fatal viral diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d03be1eda20beb3158be51afce10b7d
https://doi.org/10.12688/wellcomeopenres.15518.2

Ikoma Lyssavirus, Highly Divergent Novel Lyssavirus in an African Civet1

Autor: Sarah Cleaveland, Machunde Bigambo, Ashley C. Banyard, Chanasa Ngeleja, Lorraine M. McElhinney, Charles E. Rupprecht, Daniel T. Haydon, Denise A. Marston, Tiziana Lembo, Anthony R. Fooks, Katie Hampson, Daniel L. Horton

Publikováno v: Emerging Infectious Diseases

Evidence in support of a novel lyssavirus was obtained from brain samples of an African civet in Tanzania. Results of phylogenetic analysis of nucleoprotein gene sequences from representative Lyssavirus species and this novel lyssavirus provided stro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a647c10450d79965c865c210f01d3516
http://europepmc.org/articles/PMC3309678