Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Chanan Shaul"'
Autor:
Itay Chen, Shalom Eligal, Ori Menahem, Riki Salem, Jean-Yves Sichel, Ronen Perez, Chanan Shaul
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionThe widely accepted treatment for sudden sensorineural hearing loss (SSNHL) is corticosteroid treatment (oral or intratympanic). The main goal of this work is to define the significance of the time between symptom onset and treatment init
Externí odkaz:
https://doaj.org/article/b0464374655e4550b34debcc53ef477b
Autor:
Itay Chen, Ronen Perez, Shalom Eligal, Ori Menahem, Riki Salem, Jean-Yves Sichel, Chanan Shaul
Publikováno v:
Applied Sciences, Vol 13, Iss 14, p 8546 (2023)
The main treatment approaches for sudden sensorineural hearing loss (SSNHL) involve oral and intratympanic corticosteroids, but their efficacy remains controversial. The study objective was to evaluate the benefit of oral corticosteroids followed by
Externí odkaz:
https://doaj.org/article/41e99629de4240879b15a85c03e071ee
Publikováno v:
Journal of International Advanced Otology, Vol 16, Iss 3, Pp 323-327 (2020)
Externí odkaz:
https://doaj.org/article/c56c57d4b76245219c28099a1d6ff7a1
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The pharmacokinetics of CYP2C9 substrates is characterized by substantial interethnic variability. The objective of the study was to compare CYP2C9 activity by using Phenytoin Metabolic Ratio (PMR) between Ethiopian and non-Ethiopian Jews. PMR was de
Externí odkaz:
https://doaj.org/article/284878a50d6347cd98961944e41a45af
Publikováno v:
Applied Sciences, Vol 11, Iss 9, p 4144 (2021)
Although malpositioning of the cochlear implant (CI) electrode array is rare in patients with normal anatomy, when occurring it may result in reduced hearing outcome. In addition to intraoperative electrophysiologic tests, imaging is an important mod
Externí odkaz:
https://doaj.org/article/5af0570231804cbcb7fb7b3450e9eb72
Autor:
Reem Odi, David Bibi, Bella Shusterman, Natalia Erenburg, Chanan Shaul, Claudiu T. Supuran, Alessio Nocentini, Meir Bialer
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3361 (2021)
We recently reported a new class of carbamate derivatives as anticonvulsants. Among these, 3-methylpentyl(4-sulfamoylphenyl)carbamate (MSPC) stood out as the most potent compound with ED50 values of 13 mg/kg (i.p.) and 28 mg/kg (p.o.) in the rat maxi
Externí odkaz:
https://doaj.org/article/9d3d1656adab450cad1d26ba58da1a3c
Publikováno v:
Clinical Pharmacokinetics. 61:1187-1198
CYP2C9 is a member of the cytochrome P450 (CYP) superfamily responsible for the metabolism of 16% of drugs that undergo oxidative metabolism. The activity of CYP2C9 exhibits marked inter-individual variability, which translates into prominent differe
Publikováno v:
Clinical Pharmacology & Therapeutics. 112:156-163
Cytochrome P450 2C9 (CYP2C9) is responsible for the oxidative metabolism of about 15% of commonly used drugs, some of which are characterized by a narrow therapeutic window. CYP2C9 is highly polymorphic, and over 60 alleles have been described. CYP2C
Publikováno v:
Epilepsia.
Publikováno v:
Otology & Neurotology. 41:1341-1349
Objective: Infectious complications occurring in cochlear implant (CI) recipients is of potentially major impact. A better understanding of severe infections in this cohort is necessary. Design: Single-center, retrospective cohort study. Level of Evi