Výsledky vyhledávání - "ChanSu Jeong"

Akademický článek

Substitution of acidic residues near the catalytic Glu131 leads to human HYAL1 activity at neutral pH via charge-charge interactions.

Autor: Tu Anh Nguyen, Trang Hoang, Thu-Thuy Nguyen, ChanSu Jeong, Trang Van Tran, Mal-Gi Choi, ChangWoo Lee

Publikováno v: PLoS ONE, Vol 19, Iss 8, p e0308370 (2024)

Human hyaluronidase 1 (HYAL1) and PH20 play vital roles in degrading hyaluronic acids through the substrate-assisted double displacement mechanism. While HYAL1, a lysosomal enzyme, functions optimally under acidic conditions, PH20, a sperm surface hy

Externí odkaz: https://doaj.org/article/ed164a1afa0f43d8b2de2af29f67744a

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Akademický článek

Tyr76 is essential for the cold adaptation of a class II glutaredoxin 4 with a heat‐labile structure from the Arctic bacterium Sphingomonas sp.

Autor: Trang Hoang, ChanSu Jeong, Sei‐Heon Jang, ChangWoo Lee

Publikováno v: FEBS Open Bio, Vol 13, Iss 3, Pp 500-510 (2023)

Glutaredoxins (Grxs) are small proteins that share a well‐conserved thioredoxin (Trx)‐fold and participate in many biological processes. This study examined the cold adaptation mechanism of a Fe‐S cluster binding class II Grx4 (SpGrx4) from the

Externí odkaz: https://doaj.org/article/88bd6d7f694942fd983f90b3246b7dab

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