Zobrazeno 1 - 10
of 558
pro vyhledávání: '"Chan hee Lee"'
Interleukin-2 improves insulin sensitivity through hypothalamic sympathetic activation in obese mice
Autor:
Subin Moon, Yejin Park, Sooyeon Jang, Saeha Kim, Dan-Gyeong Song, Dae-Chul Shin, Chan Hee Lee
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Background IL-2 regulates T cell differentiation: low-dose IL-2 induces immunoregulatory Treg differentiation, while high-dose IL-2 acts as a potent activator of cytotoxic T cells and NK cells. Therefore, high-dose IL-2 has been studied for
Externí odkaz:
https://doaj.org/article/6cb8a07e15ed40088848993a384e3abd
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-15 (2024)
Abstract Effective enzyme stabilization through immobilization is essential for the functional usage of enzymatic reactions. We propose a new method for synthesizing elastic hydroxyapatite microgel (E-HAp-M) materials and immobilizing lipase using th
Externí odkaz:
https://doaj.org/article/e0eb7fab15f7491f8da00e05202528d7
Autor:
Jae Woo Park, Se Eun Park, Wuhyun Koh, Won Hee Jang, Jong Han Choi, Eun Roh, Gil Myoung Kang, Seong Jun Kim, Hyo Sun Lim, Chae Beom Park, So Yeon Jeong, Sang Yun Moon, Chan Hee Lee, Sang Yeob Kim, Hyung Jin Choi, Se Hee Min, C. Justin Lee, Min-Seon Kim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Nicotinamide adenine dinucleotide (NAD)+ serves as a crucial coenzyme in numerous essential biological reactions, and its cellular availability relies on the activity of the nicotinamide phosphoribosyltransferase (NAMPT)-catalyzed salvage pa
Externí odkaz:
https://doaj.org/article/76bd7a81ac16438d856a226c7ca54b56
Publikováno v:
Endocrinology and Metabolism, Vol 39, Iss 1, Pp 1-11 (2024)
5´-Adenosine monophosphate (AMP)-activated protein kinase (AMPK), a cellular energy sensor, is an essential enzyme that helps cells maintain stable energy levels during metabolic stress. The hypothalamus is pivotal in regulating energy balance withi
Externí odkaz:
https://doaj.org/article/8adba0c3662f43c48e0c885cc47b3dca
Autor:
Euna Cho, Min Ho An, Yi Sle Lee, Eun Jin Ryu, You Ra Lee, So Youn Park, Ye Ji Kim, Chan Hee Lee, Dayoung Oh, Min Seo Kim, Nam Deuk Kim, Jae-Joon Kim, Young Mi Hong, Mong Cho, Tae Ho Hwang
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109256- (2024)
Summary: To address the challenge of solid tumor targeting in CAR-T therapy, we utilized the A56 antigen, which is uniquely expressed on a diverse range of cancer cells following the systemic administration of an oncolytic vaccinia virus (OVV). Immun
Externí odkaz:
https://doaj.org/article/1f668d3a01bf40ffb6bbd8b175b87b6a
Autor:
Jae Woo Park, Eun Roh, Gil Myoung Kang, So Young Gil, Hyun Kyong Kim, Chan Hee Lee, Won Hee Jang, Se Eun Park, Sang Yun Moon, Seong Jun Kim, So Yeon Jeong, Chae Beom Park, Hyo Sun Lim, Yu Rim Oh, Han Na Jung, Obin Kwon, Byung Soo Youn, Gi Hoon Son, Se Hee Min, Min-Seon Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Nicotinamide phosphoribosyl transferase (NAMPT) is a critical regulator of cellular nicotinamide adenine dinucleotide (NAD)+ levels. Here, the authors show that blood NAMPT contributes to the circadian rhythm generation of locomotor activity and ener
Externí odkaz:
https://doaj.org/article/1ae6309a19ce496a8d96ad2bf3643e37
Publikováno v:
Heliyon, Vol 9, Iss 10, Pp e20925- (2023)
In this research, the geyser phenomenon occurring in a small-diameter two-phase closed thermosyphon (TPCT) was observed and the instability of the device was discussed. Geyser phenomena interfere with the natural circulation of internal working fluid
Externí odkaz:
https://doaj.org/article/220a91acac014ff084e10348a0b7216e
Publikováno v:
The Korean Journal of Internal Medicine, Vol 38, Iss 1, Pp 125-133 (2023)
Background/Aims Women with rheumatoid arthritis (RA) are often diagnosed with the disease during their reproductive years; however, its incidence and prevalence among women of childbearing age have not been studied. The objective of this study was to
Externí odkaz:
https://doaj.org/article/f0e041022ca7433ebb1696f97e06d2a8
Autor:
Yoseph Toni Wijaya, Tania Setiawan, Ita Novita Sari, Keunwan Park, Chan Hee Lee, Kae Won Cho, Yun Kyung Lee, Jae‐Young Lim, Jeong Kyo Yoon, Sae Hwan Lee, Hyog Young Kwon
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 6, Pp 3149-3162 (2022)
Abstract Background The effects of some drugs, aging, cancers, and other diseases can cause muscle wasting. Currently, there are no effective drugs for treating muscle wasting. In this study, the effects of ginsenoside Rd (GRd) on muscle wasting were
Externí odkaz:
https://doaj.org/article/7a7d605e290e4e02ae7f83b96ff66427
Publikováno v:
The Korean Journal of Internal Medicine, Vol 37, Iss 6, Pp 1250-1259 (2022)
Background/Aims We aimed to estimate the prevalence of comorbidities and medication use in Korean women with rheumatic diseases (RDs) during their childbearing years. Methods We included women aged 20 to 44 years with seropositive rheumatoid arthriti
Externí odkaz:
https://doaj.org/article/0c250d4f548e49cea060a31b0bec86c7