Výsledky vyhledávání - "Chan Yeong Kwak"

Assessing Quality and Risk of Bias in Experimental Studies on Clinical Nursing

Autor: Kyoung Eun Lee, Sungjae Kim, Jae Sim Jeong, Eul Soon Kim, Jeong Soon Kwon, Kwang Ok Park, Kyung-Sook Lee, Joo Hyun Kim, Chan Yeong Kwak, Myoung Ae Choe, Keum Soon Kim, Kyung-Choon Lim, Kyung Hee Kim

Publikováno v: Korean Society of Evidence-Based Nursing. 6:22-30

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da7a62739cf45b2d54ce8dcd7655f204
https://doi.org/10.54003/kebn.2018.6.1.22

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Enhancing the sialylation of recombinant EPO produced in CHO cells via the inhibition of glycosphingolipid biosynthesis

Autor: Seung-Yeol Park, Jung Hoe Kim, Makoto Ito, Chan Yeong Kwak, Chung Geun Lee, Nozomu Okino

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reports

Sialylation regulates the in vivo half-life of recombinant therapeutic glycoproteins, affecting their therapeutic efficacy. Levels of the precursor molecule cytidine monophospho-N-acetylneuraminic acid (CMP-Neu5Ac) are considered a limiting factor in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d967fece450b2688592b1dc271aaea
https://doi.org/10.1038/s41598-017-13609-4

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Globoside promotes activation of ERK by interaction with the epidermal growth factor receptor

Autor: Chan Yeong Kwak, Jung Hoe Kim, James A. Shayman, Seung-Yeol Park

Publikováno v: Biochimica et Biophysica Acta (BBA) - General Subjects. 1820:1141-1148

Background Globoside (Gb4), a globo-series glycosphingolipid (GSL), has been characterized as a stage-specific embryonic antigen (SSEA), and is highly expressed during embryogenesis as well as in cancer tissues. However, the functional role and molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015ad3f5611e56c01d70099256d316c0
https://doi.org/10.1016/j.bbagen.2012.04.008

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Effect of mild-thiol reducing agents and alpha2,3-sialyltransferase expression on secretion and sialylation of recombinant EPO in CHO cells

Autor: Jung Hoe Kim, Kern Hee Chang, One Choi, Chan Yeong Kwak, Yeon Tae Jeong

Publikováno v: Journal of microbiology and biotechnology. 23(5)

We have previously reported that N-acetylcysteine (NAC) not only delayed apoptosis but also enhanced the production of recombinant erythropoietin (EPO) in Chinese hamster ovary (CHO) cell culture. To investigate the production enhancement mechanism,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff84e2b59104d2c4e99e384705e8e7f
https://pubmed.ncbi.nlm.nih.gov/23648861

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