Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Chan K. N. K. Chion"'
Autor:
Catharina Jacoba Maria Doggen, James T. B. Crawley, Frits R. Rosendaal, David A. Lane, Chan K. N. K. Chion
Publikováno v:
Blood. 109:1998-2000
Von Willebrand factor (VWF) mediates the tethering/adhesion of platelets at sites of vascular injury. This function depends on its multimeric size, which is controlled by ADAMTS13. We measured plasma ADAMTS13 and VWF antigen levels by enzyme-linked i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a563507c2191f5170e9da107d115dea4
https://doi.org/10.1182/blood-2006-07-038166
https://doi.org/10.1182/blood-2006-07-038166
Autor:
Anuja Shah, Chan K. N. K. Chion, Rens de Groot, David A. Lane, James T. B. Crawley, Michelle D. Gardner
Publikováno v:
Blood. 113(5)
ADAMTS13 regulates the multimeric size of von Willebrand factor (VWF). Its function is highly dependent upon Ca2+ ions. Using the initial rates of substrate (VWF115, VWF residues 1554-1668) proteolysis by ADAMTS13 preincubated with varying Ca2+ conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28333547ea5245fe33e8b4b381631c67
https://pubmed.ncbi.nlm.nih.gov/19047683
https://pubmed.ncbi.nlm.nih.gov/19047683
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 5
Following vascular injury, blood loss is controlled by the mechanisms of hemostasis. During this process, the serine proteinase, thrombin, is generated both locally and rapidly at sites of vessel damage. It plays a pivotal role in clot promotion and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea1272f12633f09f756f0da6a8b00334
https://pubmed.ncbi.nlm.nih.gov/17635715
https://pubmed.ncbi.nlm.nih.gov/17635715
Publikováno v:
Journal of Thrombosis and Haemostasis
Summary. Background: The multimeric size and platelettethering function of von Willebrand factor (VWF) are modulated by the plasma metalloprotease, a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS-13). In vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7591df6cc4cc47cebc00272f2a3ec2
https://pubmed.ncbi.nlm.nih.gov/17355572
https://pubmed.ncbi.nlm.nih.gov/17355572