Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Chan Hyeong Lee"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16375 (2023)
Epigenetic dysregulation, particularly alterations in DNA methylation and hydroxymethylation, plays a pivotal role in cancer initiation and progression. Ten-eleven translocation (TET) proteins catalyze the successive oxidation of 5-methylcytosine (5m
Externí odkaz:
https://doaj.org/article/7bfb692a18a74141b13fef036a3145bb
Autor:
Seul Gi Lee, Seon Min Woo, Seung Un Seo, Chan-Hyeong Lee, Moon-Chang Baek, Se Hwan Jang, Zee Yong Park, Simmyung Yook, Ju-Ock Nam, Taeg Kyu Kwon
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 2, Pp 383-394 (2024)
Abstract M2-like tumor-associated macrophages (TAMs) are risk factors for cancer progression and metastasis. However, the mechanisms underlying their polarization are still not fully understood. Although cathepsin D (Cat D) has been reported as a pro
Externí odkaz:
https://doaj.org/article/3b2f5abfaf9c44249e26630cf6332b95
Autor:
Ju‐Hyun Bae, Chan‐Hyeong Lee, Dokyung Jung, Kyungmoo Yea, Byoung‐Joon Song, Hakho Lee, Moon‐Chang Baek
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Although the isolation and counting of small extracellular vesicles (sEVs) are essential steps in sEV research, an integrated method with scalability and efficiency has not been developed. Here, we present a scalable and ready‐to‐use ext
Externí odkaz:
https://doaj.org/article/6461b5281cc44b9eb099b6c059b3fe98
Autor:
Jung Min Shin, Chan‐Hyeong Lee, Soyoung Son, Chan Ho Kim, Jae Ah Lee, Hyewon Ko, Sol Shin, Seok Ho Song, Seong‐Sik Park, Ju‐Hyun Bae, Ju‐Mi Park, Eun‐Ji Choe, Moon‐Chang Baek, Jae Hyung Park
Publikováno v:
Advanced Science, Vol 9, Iss 5, Pp n/a-n/a (2022)
Abstract Despite their potent antitumor activity, clinical application of immune checkpoint inhibitors has been significantly limited by their poor response rates (
Externí odkaz:
https://doaj.org/article/47f461ab66a04e4d8a5b2484253a2d2c
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1660 (2022)
According to clinical studies, statins improve the efficacy of programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) blockade therapy for breast cancer; however, the underlying mechanisms are unclear. Herein, we showed that atorvastatin (ATO) dec
Externí odkaz:
https://doaj.org/article/691791fe70c44b229d4dbf13d71de721
Autor:
Eun-Ju Im, Chan-Hyeong Lee, Pyong-Gon Moon, Gunassekaran Gowri Rangaswamy, Byungheon Lee, Jae Man Lee, Jae-Chul Lee, Jun-Goo Jee, Jong-Sup Bae, Taeg-Kyu Kwon, Keon-Wook Kang, Myeong-Seon Jeong, Joo-Eun Lee, Hyun-Suk Jung, Hyun-Joo Ro, Sangmi Jun, Wonku Kang, Seung-Yong Seo, Young-Eun Cho, Byoung-Joon Song, Moon-Chang Baek
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Extracellular vesicles are released from cells and permit communication between different cell types. Here, the authors identify that the FDA approved antibiotic sulfisoxazole, can block the release of these vesicles in breast cancer cells resulting
Externí odkaz:
https://doaj.org/article/564a9fb0ea3542299cb37cacb0869df3
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background Small extracellular vesicles (small-EVs) are membranous vesicles that contain unique information regarding the condition of cells and contribute to the recruitment and reprogramming of components associated with the tumor environm
Externí odkaz:
https://doaj.org/article/d5259f7b23e741f79ef19348876c462b
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/dff363d760f64edc80d6e180a96061f7
Publikováno v:
The Korean Data Analysis Society. 24:585-597
Autor:
Chan-Hyeong, Lee, Ju-Hyun, Bae, Eun-Ji, Choe, Ju-Mi, Park, Seong-Sik, Park, Hee Jin, Cho, Byoung-Joon, Song, Moon-Chang, Baek
Publikováno v:
Theranostics. 12:1971-1987
Extracellular vesicles (EVs) carrying tumor cell-derived programmed death-ligand 1 (PD-L1) interact with programmed death 1 (PD-1)-producing T cells, thus significantly lowering a patient's response to immune checkpoint blockade drugs. No drug that r