Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chan Hee J. Choi"'
Autor:
Chan Hee J Choi, William Barr, Samir Zaman, Corey Model, Annsea Park, Mascha Koenen, Zeran Lin, Sarah K Szwed, Francois Marchildon, Audrey Crane, Thomas S Carroll, Henrik Molina, Paul Cohen
Publikováno v:
eLife, Vol 11 (2022)
While dysregulation of adipocyte endocrine function plays a central role in obesity and its complications, the vast majority of adipokines remain uncharacterized. We employed bio-orthogonal non-canonical amino acid tagging (BONCAT) and mass spectrome
Externí odkaz:
https://doaj.org/article/c6f61321c017407b97cd6735f2779d52
Autor:
Chan Hee J Choi, William Barr, Samir Zaman, Corey Model, Annsea Park, Mascha Koenen, Zeran Lin, Sarah K Szwed, Francois Marchildon, Audrey Crane, Thomas S Carroll, Henrik Molina, Paul Cohen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2505b399c36f082d0e200648d675d65
https://doi.org/10.7554/elife.81559.sa2
https://doi.org/10.7554/elife.81559.sa2
Autor:
Chan Hee J Choi, Paul Cohen
Publikováno v:
eLife, Vol 6 (2017)
Experiments on mice show that an enzyme called DNA methyltransferase 3a is involved in insulin resistance via an epigenetic mechanism.
Externí odkaz:
https://doaj.org/article/cc3ff6c0a4f34262be4336b59090f734
Publikováno v:
Diabetes. 70
Adipocytes play a central role in obesity, type 2 diabetes, and metabolic disease. White adipocytes store excess energy, and brown adipocytes dissipate chemical energy into heat. In addition to these bioenergetics functions, adipocytes also have impo
Autor:
Bo Zhao, Keya Zhang, Karan Bhuripanyo, Chan Hee J Choi, Eric B Villhauer, Heng Li, Ning Zheng, Hiroaki Kiyokawa, Hermann Schindelin, Jun Yin
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70312 (2013)
The C-terminal peptides of ubiquitin (UB) and UB-like proteins (UBLs) play a key role in their recognition by the specific activating enzymes (E1s) to launch their transfer through the respective enzymatic cascades thus modifying cellular proteins. U
Externí odkaz:
https://doaj.org/article/e98b3b659bb94f6f8d0f1bfa4bcaac2d
Autor:
Chan Hee J. Choi, Paul Cohen
Publikováno v:
Experimental Cell Research. 360:6-11
In addition to storing and mobilizing energy, adipocytes secrete circulating factors to signal to other tissues and coordinate energy metabolism. These functions can become disrupted in the setting of obesity, contributing to the development of diabe
Autor:
Tania Das Banerjee, Thomas Topilko, Paul Cohen, Varun Bhave, Nicolas Renier, Esteban A. Engel, Kyle Pellegrino, Marc Schneeberger, Putianqi Wang, Alexander R. Nectow, Luca Parolari, Bindiben Patel, Zhuhao Wu, Xiaofei Yu, Jeffrey M. Friedman, Chan Hee J. Choi
Publikováno v:
Cell
Homeostatic control of core body temperature is essential for survival. Temperature is sensed by specific neurons, in turn eliciting both behavioral (i.e., locomotion) and physiologic (i.e., thermogenesis, vasodilatation) responses. Here, we report t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45017d9e484fef9f3061a711b4a71c5f
https://europepmc.org/articles/PMC7481042/
https://europepmc.org/articles/PMC7481042/
Publikováno v:
Diabetes. 68
Fat cells or adipocytes play a central role in obesity, diabetes, and metabolic disease. White adipocytes store excess energy in the form of triglycerol, and brown adipocytes dissipate chemical energy into heat. In addition to these bioenergetics fun
Autor:
Lily Nguyen, Audrey Crane, Paul Cohen, Marc Tessier-Lavigne, Saba Tegegne, Sarah E. Ackerman, François Marchildon, Zhuhao Wu, Jingyi Chi, Chan Hee J. Choi
Publikováno v:
Cell metabolism. 27(1)
While the cell-intrinsic pathways governing beige adipocyte development and phenotype have been increasingly delineated, comparatively little is known about how beige adipocytes interact with other cell types in fat. Here, we introduce a whole-tissue
Autor:
Jun Yin, Hermann Schindelin, Eric B. Villhauer, Keya Zhang, Hiroaki Kiyokawa, Karan Bhuripanyo, Ning Zheng, Heng Li, Chan Hee J. Choi, Bo Zhao
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70312 (2013)
PLoS ONE
PLoS ONE
The C-terminal peptides of ubiquitin (UB) and UB-like proteins (UBLs) play a key role in their recognition by the specific activating enzymes (E1s) to launch their transfer through the respective enzymatic cascades thus modifying cellular proteins. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba66079cd34e8ca6b07ea42ab3a73f1f
https://opus.bibliothek.uni-wuerzburg.de/files/12847/077_Zhao_Plos_One.pdf
https://opus.bibliothek.uni-wuerzburg.de/files/12847/077_Zhao_Plos_One.pdf