Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Chan Aye Thu"'
Autor:
Kerry Marie Goodman, Rotem Rubinstein, Chan Aye Thu, Seetha Mannepalli, Fabiana Bahna, Göran Ahlsén, Chelsea Rittenhouse, Tom Maniatis, Barry Honig, Lawrence Shapiro
Publikováno v:
eLife, Vol 5 (2016)
Stochastic cell-surface expression of α-, β-, and γ-clustered protocadherins (Pcdhs) provides vertebrate neurons with single-cell identities that underlie neuronal self-recognition. Here we report crystal structures of ectodomain fragments compris
Externí odkaz:
https://doaj.org/article/5d4ce16104d24b35b29a6deed02c523e
Autor:
Kerry M, Goodman, Rotem, Rubinstein, Hanbin, Dan, Fabiana, Bahna, Seetha, Mannepalli, Göran, Ahlsén, Chan, Aye Thu, Rosemary V, Sampogna, Tom, Maniatis, Barry, Honig, Lawrence, Shapiro
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(46)
Pcdhs are cell surface homophilic recognition proteins expressed stochastically to assign individual identities to each neuron. These individual identities ensure repulsion between neurites from the same cell and ensure that neurites from different c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ca2b541d35cec37c28e2279472e7395
https://pubmed.ncbi.nlm.nih.gov/29087338
https://pubmed.ncbi.nlm.nih.gov/29087338
Autor:
Fabiana Bahna, Barry Honig, Tom Maniatis, Seetha Mannepalli, Goran Ahlsen, Rosemary V. Sampogna, Chan Aye Thu, Lawrence Shapiro, Rotem Rubinstein, Kerry M. Goodman, Hanbin Dan
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Significance Pcdhs are cell surface homophilic recognition proteins expressed stochastically to assign individual identities to each neuron. These individual identities ensure repulsion between neurites from the same cell and ensure that neurites fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c9e509096187d4db138c97ce4148f03
https://doi.org/10.1073/pnas.1713449114
https://doi.org/10.1073/pnas.1713449114
Autor:
Chan Aye Thu, Rotem Rubinstein, Lawrence Shapiro, Barry Honig, Weisheng V. Chen, Klara Felsovalyi, Juan Carlos Tapia, Holly N. Wolcott, Maxime Chevee, Tom Maniatis
Publikováno v:
Cell. 158(5):1045-1059
SummaryIndividual mammalian neurons stochastically express distinct repertoires of α, β, and γ protocadherin (Pcdh) proteins, which function in neural circuit assembly. We report that all three subfamilies of clustered Pcdhs can engage in specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd6c7102175c5532760e6f2528a236d
Autor:
Chelsea Rittenhouse, Kerry M. Goodman, Tom Maniatis, Lawrence Shapiro, Chan Aye Thu, Rotem Rubinstein, Barry Honig, Fabiana Bahna, Seetha Mannepalli, Goran Ahlsen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae3023d2c8fc990a48e5a74baac73994
https://doi.org/10.7554/elife.20930.064
https://doi.org/10.7554/elife.20930.064
Autor:
Chelsea Rittenhouse, Barry Honig, Lawrence Shapiro, Fabiana Bahna, Goran Ahlsen, Seetha Mannepalli, Chan Aye Thu, Tom Maniatis, Rotem Rubinstein, Kerry M. Goodman
Clustered protocadherin proteins (α-, β-, and γ-Pcdhs) provide a high level of cell-surface diversity to individual vertebrate neurons, engaging in highly specific homophilic interactions to mediate important roles in mammalian neural circuit deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daa4a4c5477dbdb5ed19a684f6585193
https://europepmc.org/articles/PMC4873334/
https://europepmc.org/articles/PMC4873334/
Autor:
Chan Aye Thu, Barry Honig, Tony Hunter, Brygida Bisikirska, Donald Petrey, Domenico Accili, Li Qiang, Qiangfeng Cliff Zhang, Celine Lefebvre, Andrea Califano, Tom Maniatis, Yu Shi, Lei Deng
Publikováno v:
Nature
Protein–protein interactions, essential for understanding how a cell functions, are predicted using a new method that combines protein structure with other computationally and experimentally derived clues. The analysis of protein-interaction networ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5802da17095a0bbb5936ca1adf75e64d
http://europepmc.org/articles/PMC3482288
http://europepmc.org/articles/PMC3482288
Autor:
Joshua R. Sanes, Eric J. Geiman, Bosiljka Tasic, Juan Carlos Tapia, Chan Aye Thu, Brad A. Friedman, Tom Maniatis, Courtney A. Smith, Chiamaka L. Nwakeze, Weisheng V. Chen, Julie L. Lefebvre, Francisco J. Alvarez
Publikováno v:
Neuron. 75(3):402-409
SummaryThe mammalian Protocadherin (Pcdh) alpha, beta, and gamma gene clusters encode a large family of cadherin-like transmembrane proteins that are differentially expressed in individual neurons. The 22 isoforms of the Pcdhg gene cluster are divers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3a6c2bef606097c4cf5efc00c81966
Autor:
Hanbin Dan, Barry Honig, Rosemary V. Sampogna, Chan Aye Thu, Lawrence Shapiro, Seetha Mannepalli, Kerry M. Goodman, Rotem Rubinstein, Julia Brasch, Fabiana Bahna, Tom Maniatis
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 73:a50-a50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6a7bdaf679877d3c66dfab265401871
https://doi.org/10.1107/s0108767317099500
https://doi.org/10.1107/s0108767317099500
Publikováno v:
IUBMB life. 64(10)
Transforming growth factor β-activated kinase 1 (TAK1) is a key regulator of the innate immunity and the proinflammatory signaling pathway. In response to interleukin-1, tumor necrosis factor-α, and toll-like receptor agonists, it mediates the acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3179cae077917a48a8f7cfdf4c7297f0
https://pubmed.ncbi.nlm.nih.gov/22941947
https://pubmed.ncbi.nlm.nih.gov/22941947