Revealing invisible cell phenotypes with conditional generative modeling.

Autor: Lamiable A; Computational Bioimaging and Bioinformatics, Institut de Biologie de l'Ecole Normale Supérieure, PSL University, 46, rue d'Ulm, 75005, Paris, France., Champetier T; Computational Bioimaging and Bioinformatics, Institut de Biologie de l'Ecole Normale Supérieure, PSL University, 46, rue d'Ulm, 75005, Paris, France.; Ksilink, 16 rue d'Ankara, 67000, Strasbourg, France., Leonardi F; Computational Bioimaging and Bioinformatics, Institut de Biologie de l'Ecole Normale Supérieure, PSL University, 46, rue d'Ulm, 75005, Paris, France.; Université Paris-Cité, MERIT, IRD, F-75006, Paris, France., Cohen E; Computational Bioimaging and Bioinformatics, Institut de Biologie de l'Ecole Normale Supérieure, PSL University, 46, rue d'Ulm, 75005, Paris, France., Sommer P; Ksilink, 16 rue d'Ankara, 67000, Strasbourg, France., Hardy D; Histopathology Platform, Institut Pasteur, F-75015, Paris, France., Argy N; Université Paris-Cité, MERIT, IRD, F-75006, Paris, France.; Laboratoire de parasitologie-mycologie, Hôpital Bichat-Claude bernard, APHP, Paris, France., Massougbodji A; Institut de Recherche Clinique du Bénin, Abomey-Calavi, Benin., Del Nery E; Biophenics, Institut Curie, PSL Research University, Department of Translational Research, Cell and Tissue Imaging Facility (PICT-IBiSA), 26 rue d'Ulm, 75005, Paris, France., Cottrell G; Université Paris-Cité, MERIT, IRD, F-75006, Paris, France., Kwon YJ; Ksilink, 16 rue d'Ankara, 67000, Strasbourg, France. yong-jun.kwon@lih.lu.; Personalized Therapy Discovery, Department of Oncology, Luxembourg Institute of Health, Dudelange, Luxembourg. yong-jun.kwon@lih.lu., Genovesio A; Computational Bioimaging and Bioinformatics, Institut de Biologie de l'Ecole Normale Supérieure, PSL University, 46, rue d'Ulm, 75005, Paris, France. auguste.genovesio@ens.psl.eu.

Publikováno v: Nature communications [Nat Commun] 2023 Oct 11; Vol. 14 (1), pp. 6386. Date of Electronic Publication: 2023 Oct 11.

Studying 3D cell cultures in a microfluidic droplet array under multiple time-resolved conditions

Autor: Champetier T, Raphaël F.-X. Tomasi, Charles N. Baroud, Sébastien Sart

The relevance of traditional cell cultures to cellular behavior in vivo is limited, since the two-dimensional (2D) format does not appropriately reproduce the microenvironment that regulates cell functions. In this context, spheroids are an appealing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73eba38dca9a21940959614adef447f2
https://doi.org/10.1101/407759

Individual Control and Quantification of 3D Spheroids in a High-Density Microfluidic Droplet Array.

Autor: Tomasi RF; LadHyX and Department of Mechanics, Ecole Polytechnique, CNRS, 91128 Palaiseau, France; Physical Microfluidics and Bio-Engineering, Department of Genomes and Genetics, Institut Pasteur, 75015 Paris, France., Sart S; LadHyX and Department of Mechanics, Ecole Polytechnique, CNRS, 91128 Palaiseau, France; Physical Microfluidics and Bio-Engineering, Department of Genomes and Genetics, Institut Pasteur, 75015 Paris, France., Champetier T; LadHyX and Department of Mechanics, Ecole Polytechnique, CNRS, 91128 Palaiseau, France., Baroud CN; LadHyX and Department of Mechanics, Ecole Polytechnique, CNRS, 91128 Palaiseau, France; Physical Microfluidics and Bio-Engineering, Department of Genomes and Genetics, Institut Pasteur, 75015 Paris, France. Electronic address: charles.baroud@pasteur.fr.

Publikováno v: Cell reports [Cell Rep] 2020 May 26; Vol. 31 (8), pp. 107670.

Implementing patient derived organoids in functional precision medicine for patients with advanced colorectal cancer.

Autor: Cartry, Jérôme¹ (AUTHOR) jerome.cartry@gustaveroussy.fr, Bedja, Sabrina¹ (AUTHOR), Boilève, Alice¹ (AUTHOR), Mathieu, Jacques R. R.¹ (AUTHOR), Gontran, Emilie¹ (AUTHOR), Annereau, Maxime² (AUTHOR), Job, Bastien³ (AUTHOR), Mouawia, Ali¹ (AUTHOR), Mathias, Pierre¹ (AUTHOR), De Baère, Thierry^4,5 (AUTHOR), Italiano, Antoine^6,7 (AUTHOR), Besse, Benjamin^7,8 (AUTHOR), Sourrouille, Isabelle⁹ (AUTHOR), Gelli, Maximiliano^1,9 (AUTHOR), Bani, Mohamed-Amine¹⁰ (AUTHOR), Dartigues, Peggy¹⁰ (AUTHOR), Hollebecque, Antoine^6,8 (AUTHOR), Smolenschi, Cristina^6,8 (AUTHOR), Ducreux, Michel^1,8 (AUTHOR), Malka, David^1,8,11 (AUTHOR)

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 10/25/2023, Vol. 42 Issue 1, p1-17. 17p.

Deep learning-assisted concentration gradient generation for the study of 3D cell cultures in hydrogel beads of varying stiffness.

Autor: Anagnostidis, Vasileios, Tiwari, Anuj, Gielen, Fabrice

Publikováno v: Frontiers in Bioengineering & Biotechnology; 2024, p1-11, 11p