Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Chamitha, Weeramange"'
Autor:
Chamitha Weeramange, Ryan J. Rafferty, Asantha Fernando, Johnathan Dallman, Shashika Perera, Thi Thu Ha Nguyen, Ashabha Lansakara
Publikováno v:
ChemMedChem. 16:1631-1639
Discovering therapeutic agents: New bioactive agents, either as sole or combinational agents, have been constructed through the synthetic manipulation of the intermediates within the total synthesis of the uvaretin class of natural products. It was f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbcb74b5cd15e669b49801f0ec5caccd
https://doi.org/10.1002/cmdc.202001010
https://doi.org/10.1002/cmdc.202001010
Autor:
Chamitha Weeramange, Thi D.T. Nguyen, Johnathan Dallman, Ashabha Lansakara, Ryan J. Rafferty, Wasundara Hulangamuwa
Publikováno v:
MedChemComm. 10:717-725
6-Thiopurine (6TP) is a potent cytotoxic agent that is a clinically prescribed anti-metabolite employed in the treatment of numerous blood cancers since 1952. However, its reported severe toxicities limit its general usage in the clinic. We previousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cf1bf56172ac5edc9222e8411cd2b13
https://doi.org/10.1039/c9md00010k
https://doi.org/10.1039/c9md00010k
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 151:106-115
6-Thiopurine (6TP) is an actively prescribed drug in the treatment of various diseases ranging from Crohn’s disease and other inflammatory diseases to acute lymphocytic leukemia and non-Hodgkin’s leukemia. While 6TP has beneficial therapeutic use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88db95695bc4f0f3e91e83b30d4e537f
https://doi.org/10.1016/j.jpba.2017.12.058
https://doi.org/10.1016/j.jpba.2017.12.058
Autor:
Johnathan Dallman, Thi D.T. Nguyen, Chamitha Weeramange, Wasundara Hulangamuwa, Ashabha Lansakara, Ryan J. Rafferty
Publikováno v:
Medchemcomm
Herein, we disclose the development of a synthetic route to gain access to the uvaretin class of chalcone natural products. In this, the construction of a small library was achieved, and the collection was evaluated for cytotoxicity and other biologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382c798c7174595123058baf53cbaba3
https://europepmc.org/articles/PMC6786243/
https://europepmc.org/articles/PMC6786243/
Autor:
Chamitha, Weeramange, Ashabha, Lansakara, Johnathan, Dallman, Thi, Nguyen, Wasundara, Hulangamuwa, Ryan J, Rafferty
Publikováno v:
MedChemComm. 10(5)
6-Thiopurine (6TP) is a potent cytotoxic agent that is a clinically prescribed anti-metabolite employed in the treatment of numerous blood cancers since 1952. However, its reported severe toxicities limit its general usage in the clinic. We previousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::793d971ac174efd60e2561a8d983de42
https://pubmed.ncbi.nlm.nih.gov/31191862
https://pubmed.ncbi.nlm.nih.gov/31191862
Autor:
Prathibha Desman, Chamitha Weeramange, Olivia Haney, Anthony Fatino, Ryan J. Rafferty, Arnaldo X Torres Hernandez
6-Thiopurine (6TP) is a currently prescribed drug in the treatment of diseases ranging from Crohn's disease to acute lymphocytic leukemia. While its potent mode of action is through incorporation into DNA as a thiol mimic of deoxyguanosine, severe to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e435db595af0ecbcfc342a95400625
https://europepmc.org/articles/PMC6350761/
https://europepmc.org/articles/PMC6350761/
Publikováno v:
Journal of natural products. 80(12)
Reniochalistatin E (1) is one of the five related cyclic peptides isolated from the marine sponge Reniochalina stalagmitis. The discovery of these compounds resulted from a screening program directed toward the identification of proline-rich bioactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668b48131a3c5c9d5cba3bfc3339332b
https://pubmed.ncbi.nlm.nih.gov/29220182
https://pubmed.ncbi.nlm.nih.gov/29220182