Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Chamindi Seneviratne"'
Autor:
Amol Carl Shetty, John Sivinski, Jessica Cornell, Carrie McCracken, Lisa Sadzewicz, Anup Mahurkar, Xing-Qun Wang, Luana Colloca, Weihong Lin, Nageswara Pilli, Maureen A. Kane, Chamindi Seneviratne
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Molecular responses to alcohol consumption are dynamic, context-dependent, and arise from a complex interplay of biological and external factors. While many have studied genetic risk associated with drinking patterns, comprehensive studies i
Externí odkaz:
https://doaj.org/article/46f8d1b03a29479b885e12f242d0224f
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/431fe1c550164021af9dceb676196cf2
Autor:
Jessica Cornell, Ariana Taj, John Sivinski, Margaret Yin, Parth Bhatia, Desai Oula, Sophia Fatschel, Patricia Franklin, Jason Noel, Luana Colloca, Chamindi Seneviratne
Publikováno v:
Frontiers in Communication, Vol 7 (2022)
BackgroundThe Society of Interdisciplinary Placebo Studies (SIPS) was one of many organizations that hosted a virtual scientific conference in response to the COVID-19 pandemic restrictions. Retaining essential benefits of an in-person conference exp
Externí odkaz:
https://doaj.org/article/9b71f2cab8e544a986f0b43b3d425db7
Autor:
Chamindi Seneviratne, Amol Carl Shetty, Xinyan Geng, Carrie McCracken, Jessica Cornell, Kristin Mullins, Feng Jiang, Sanford Stass
Publikováno v:
Diagnostics, Vol 12, Iss 12, p 2897 (2022)
Lung cancers are the leading cause of cancer-related deaths worldwide. Studies have shown that non-small cell lung cancer (NSCLC), which constitutes the majority of lung cancers, is significantly more responsive to early-stage interventions. However,
Externí odkaz:
https://doaj.org/article/21416e589e734970955f8eb459b2d38e
Autor:
Bankole A Johnson, Ahmed M Elkashef, Nassima Ait-Daoud, Chamindi Seneviratne, Roberta C Kahn, Shou-Hua Li, Daniel A Bloch, Tyson H Holmes, Xin-Qun Wang, Ming D Li, Francis J Vocci, Jr.
Publikováno v:
Frontiers in Psychiatry, Vol 1 (2010)
Early-onset methamphetamine use increases the lifetime prevalence of methamphetamine dependence. An earlier onset of methamphetamine use leads to greater damage to the terminal ends of serotonin neurons, more reduction in serotonin transporter (5-HTT
Externí odkaz:
https://doaj.org/article/7a2bd91334b744d99d1c159e44a8b787
Autor:
Ming D Li, Jamie E Mangold, Chamindi Seneviratne, Guo-Bo Chen, Jennie Z Ma, Xiang-Yang Lou, Thomas J Payne
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7055 (2009)
Previous studies have demonstrated that the gamma-aminobutyric acid type B (GABA(B)) receptor plays an essential role in modulating neurotransmitter release and regulating the activity of ion channels and adenyl cyclase. However, whether the naturall
Externí odkaz:
https://doaj.org/article/7cc7dcf5e8f2425ea20f73031726f073
Autor:
Chamindi Seneviratne, David A. Gorelick, Kevin G. Lynch, Clayton Brown, Danielle Romer, Timothy Pond, Kyle Kampman, Henry R. Kranzler
Publikováno v:
Alcoholism: Clinical and Experimental Research. 46:1900-1912
In a previous study, ondansetron, a serotonin 5-HTIn this 16-week, double-blind, placebo-controlled, parallel-group clinical trial, adults with AUD were randomized to receive low-dose oral ondansetron (0.33 mg twice daily) or placebo stratified by "r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc036d218ed5aca2523e33488a44e853
https://doi.org/10.1111/acer.14932
https://doi.org/10.1111/acer.14932
Autor:
Jessica Cornell, Andrew Conchas, Xin‐Qun Wang, Jeffrey C. Fink, Hegang Chen, Maureen A. Kane, Nageswara Pilli, Nassima Ait‐Daoud, David A. Gorelick, Ming D. Li, Bankole A. Johnson, Chamindi Seneviratne
Publikováno v:
Alcoholism: Clinical and Experimental Research. 46:1888-1899
The serotonin transporter (SERT) mRNA was previously reported to be a quantitative and pathophysiology-based biomarker of heavy drinking in 5HTTLPR:LL genotype-carriers treated with ondansetron. Here, we validated the potential use of SERT mRNA for q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25bfe2e472170d45bfdde11327553fa7
https://doi.org/10.1111/acer.14931
https://doi.org/10.1111/acer.14931
Autor:
Amol Carl Shetty, John Sivinski, Jessica Cornell, Lisa Sadzewicz, Anup Mahurkar, Xing-Qun Wang, Luana Colloca, Weihong Lin, Maureen A. Kane, Chamindi Seneviratne
Publikováno v:
medRxiv
Molecular changes associated with alcohol consumption arise from complex interactions between pharmacological effects of alcohol, psychological/placebo context surrounding drinking, and other environmental and biological factors. The goal of this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd3c793fe6acdf7678319206d9f6290
https://europepmc.org/articles/PMC10055573/
https://europepmc.org/articles/PMC10055573/
Autor:
Kristin E. Mullins, Chamindi Seneviratne, Amol C. Shetty, Feng Jiang, Robert Christenson, Sanford Stass
Publikováno v:
Clinical Biochemistry. 118:110583
Nucleic acid sequencing technologies have advanced significantly in recent years, allowing the development of liquid biopsies as new means to detect cancer biomarkers and cancer heterogenicity. Most of the assays available clinically focus on cell fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2b7f298cd272c561eaa26bbdc49a500
https://doi.org/10.1016/j.clinbiochem.2023.05.002
https://doi.org/10.1016/j.clinbiochem.2023.05.002