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Safety and efficacy of aspirin, unfractionated heparin, both, or neither during endovascular stroke treatment (MR CLEAN-MED):an open-label, multicentre, randomised controlled trial
Autor: Steen, W. van der, Graaf, R.A.V. de, Chalos, V., Lingsma, H.F., Doormaal, P.J. van, Coutinho, J.M., Emmer, B.J., Ridder, I. de, Zwam, W. van, Worp, H.B. van der, Schaaf, I. van der, Gons, R.A.R., Yo, L.S.F., Boiten, J., Wijngaard, I. van den, Hofmeijer, J., Martens, J., Schonewille, W., Vos, J.A., Tuladhar, A.M., Laat, K.F. de, Hasselt, B. van, Remmers, M., Vos, D., Rozeman, A., Elgersma, O., Uyttenboogaart, M., Bokkers, R.P.H., Tuijl, J. van, Boukrab, I., Berg, R. van den, Beenen, L.F.M., Roosendaal, S.D., Postma, A.A., Krietemeijer, M., Lycklama, G., Meijer, F.J.A., Hammer, S., Hoorn, A. van der, Yoo, A.J., Gerrits, D., Truijman, M.T.B., Zinkstok, S., Koudstaal, P.J., Manschot, S., Kerkhoff, H., Nieboer, D., Berkhemer, O., Wolff, L., Sluijs, P.M. van der, Voorst, H. van, Tolhuisen, M., Roos, Y.B.W.E.M., Majoie, C.B.L.M., Staals, J., Oostenbrugge, R.J. van, Jenniskens, S.F.M., Dijk, L.C. van, Hertog, H.M. den, Es, A.C.G.M. van, Lugt, A. van der, Dippel, D.W.J., Roozenbeek, B., MR CLEAN-MED Investigators
Publikováno v: MR CLEAN-MED Investigators 2022, ' Safety and efficacy of aspirin, unfractionated heparin, both, or neither during endovascular stroke treatment (MR CLEAN-MED) : an open-label, multicentre, randomised controlled trial ', The Lancet, vol. 399, no. 10329, pp. 1059-1069 . https://doi.org/10.1016/S0140-6736(22)00014-9
The Lancet, 399(10329), 1059-1069. ELSEVIER SCIENCE INC
The Lancet (London), 399, 1059-1069
The Lancet, 399(10329), 1059-1069. Elsevier Limited
The Lancet, 399(10329), 1059-1069. Elsevier Ltd.
The Lancet (London), 399, 10329, pp. 1059-1069
Lancet, 399(10329), 1059-1069. Elsevier Science
BACKGROUND: Aspirin and unfractionated heparin are often used during endovascular stroke treatment to improve reperfusion and outcomes. However, the effects and risks of anti-thrombotics for this indication are unknown. We therefore aimed to assess t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8953cfdde4fc4e0b25a24d129984fa64
https://research.vumc.nl/en/publications/155f1e87-ba12-4257-8269-1662795d2460
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6
Clinical and Imaging Markers Associated With Hemorrhagic Transformation in Patients With Acute Ischemic Stroke
Autor: Kranendonk, K.R. van, Treumiet, K.M., Boers, A.M.M., Berkhemer, O.A., Berg, L.A. van den, Chalos, V., Lingsma, H.F., Zwam, W.H. van, Lugt, A. van der, Oostenbrugge, R.J. van, Dippel, D.W.J., Roos, Y.B.W.E.M., Marquering, H.A., Majoie, C.B.L.M., Fransen, P.S.S., Beumer, D., Yoo, A.J., Schonewille, W.J., Vos, J.A., Nederkoorn, P.J., Wenner, M.J.H., Walderveen, M.A.A. van, Staals, J., Hofmeijer, J., Oostayen, J.A. van, Nijeholt, G.J.L.A., Boiten, J., Brouwer, P.A., Emmet, B.J., Bruijn, S.F. de, Dijk, L.C. van, Kappelle, L.J., R.H. lo, Dijk, E.J. van, Vries, J. de, Kort, P.L.M. de, Rooij, W.J.J. van, Berg, J.S.P. van den, Hassell, B.A.A.M. van, Aerden, L.A.M., Dallinga, R.J., Visser, M.C., Bot, J.C.J., Vroomen, P.C., Eshghi, O., Schreuder, T.H.C.M.L., Heijboer, R.J.J., Keizer, K., Tielbeek, A.V., Hertog, H.M. den, Gerrits, D.G., Berg-Vos, R.M. van den, Karas, G.B., Steyerberg, E.W., Flach, H.Z., Sprengers, M.E.S., Jenniskens, S.F.M., Beenen, L.F.M., Berg, R. van den, Koudstaal, P.J., MR CLEAN Investigators
Publikováno v: Stroke
Stroke, 50(8), 2037-2043. LIPPINCOTT WILLIAMS & WILKINS
Stroke, 50, 8, pp. 2037-2043
Stroke, 50(8), 2037-2043
Stroke; a journal of cerebral circulation, 50(8), 2037-2043. Lippincott Williams and Wilkins
Stroke, 50, 2037-2043
Stroke, 50(8), 2037-2043. Lippincott Williams and Wilkins
MR CLEAN Registry Investigators 2019, ' Clinical and Imaging Markers Associated With Hemorrhagic Transformation in Patients With Acute Ischemic Stroke ', Stroke, vol. 50, no. 8, pp. 2037-2043 . https://doi.org/10.1161/STROKEAHA.118.024255
Stroke, 50(8), 2037-2043. Lippincot, Williams & Wilkins
Journal of the American Heart Association, 50(8), 2037-2043. Wiley
Background and Purpose— Hemorrhagic transformation (HT) after acute ischemic stroke may cause severe neurological deterioration and affects functional outcome. Identifying patients most likely to suffer from this complication could potentially be u
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c9da5cb764330d1b8ff46b2be2db76
https://doi.org/10.1161/strokeaha.118.024255
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7
Collateral Circulation and Outcome in Atherosclerotic Versus Cardioembolic Cerebral Large Vessel Occlusion
Autor: Guglielmi, V., LeCouffe, N.E., Zinkstok, S.M., Compagne, K.C.J., Eker, R., Treurniet, K.M., Tolhuisen, M.L., Worp, H.B. van der, Jansen, I.G.H., Oostenbrugge, R.J. van, Marquering, H.A., Dippel, D.W.J., Emmer, B.J., Majoie, C.B.L.M., Roos, Y.B.W.E.M., Coutinho, J.M., Lugt, A. van der, Zwam, W.H. van, Boiten, J., Vos, J.A., Mulder, M.J.H.L., Goldhoorn, R.J.B., Kappelhof, M., Schonewille, W.J., Wermer, M.J.H., Walderveen, M.A.A. van, Staals, J., Hofmeijer, J., Martens, J.M., Nijeholt, G.J.L.A., Roozenbeek, B., Bruijn, S.F. de, Dijk, L.C. van, R.H. lo, Dijk, E.J. van, Boogaarts, H.D., Kort, P.L.M. de, Peluso, J.P., Berg, J.S.P. van den, Hasselt, B.A.A.M. van, Aerden, L.A.M., Dallinga, R.J., Uyttenboogaart, M., Eshghi, O., Schreuder, T.H.C.M.L., Heijboer, R.J.J., Keizer, K., Yo, L.S.F., Hertog, H.M. den, Sturm, E.J.C., Sprengers, M.E.S., Jenniskens, S.F.M., Berg, R. van den, Yoo, A.J., Beenen, L.F.M., Postma, A.A., Roosendaal, S.D., Kallen, B.F.W. van der, Wijngaard, I.R. van den, Es, A.C.G.M. van, Bot, J., Doormaal, P.J. van, Flach, H.Z., Lingsma, H.F., Ghannouti, N. el, Sterrenberg, M., Puppels, C., Pellikaan, W., Sprengers, R., Elfrink, M., Meris, J. de, Vermeulen, T., Geerlings, A., Vemde, G. van, Simons, T., Rijswijk, C. van, Messchendorp, G., Bongenaar, H., Bodde, K., Kleijn, S., Lodico, J., Droste, H., Wollaert, M., Jeurrissen, D., Bos, E., Drabbe, Y., Aaldering, N., Zweedijk, B., Khalilzada, M., Venema, E., Chalos, V., Geuskens, R.R., Straaten, T. van, Ergezen, S., Harmsma, R.R.M., Muijres, D., Jong, A. de, Hinsenveld, W., Berkhemer, O.A., Boers, A.M.M., Huguet, J., Groot, P.F.C., Mens, M.A., Kranendonk, K.R. van, Tolhuijsen, M.L., Alves, H., MR-CLEAN Registry Investigators
Publikováno v: Stroke, 50(12), 3360-3368. Lippincott Williams and Wilkins
Stroke
Stroke, 50(12), 3360. Lippincott Williams and Wilkins
Journal of the American Heart Association, 50(12), 3360-3368. Wiley
MR CLEAN Registry Investigators 2019, ' Collateral Circulation and Outcome in Atherosclerotic Versus Cardioembolic Cerebral Large Vessel Occlusion ', Stroke, vol. 50, no. 12, pp. 3360-3368 . https://doi.org/10.1161/STROKEAHA.119.026299
Stroke, 50(12), 3360-3368. LIPPINCOTT WILLIAMS & WILKINS
Stroke, 50, 12, pp. 3360-3368
Stroke, 50(12), 3360-3368
Stroke; a journal of cerebral circulation, 50(12), 3360-3368. Lippincott Williams and Wilkins
Stroke, 50, 3360-3368
Supplemental Digital Content is available in the text.
Background and Purpose— Due to chronic hypoperfusion, cervical atherosclerosis may promote cerebral collateral circulation. We hypothesized that patients with ischemic stroke due to cervic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1dda262861e303e96a148fe2f610a1c
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85075814426&origin=inward
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9
Multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke. The effect of periprocedural medication: Acetylsalicylic acid, unfractionated heparin, both, or neither (MR CLEAN-MED). Rationale and study design
Autor: Chalos, V, A van de Graaf, R, Roozenbeek, B, C G M van Es, A, M den Hertog, H, Staals, J, van Dijk, L, F M Jenniskens, S, J van Oostenbrugge, R, H van Zwam, W, B W E M Roos, Y, B L M Majoie, C, F Lingsma, H, van der Lugt, A, W J Dippel, D, investigators, MR CLEAN-MED, Rothwell, P
Publikováno v: Trials, 21(1):644. BioMed Central Ltd.
Trials, Vol 21, Iss 1, Pp 1-17 (2020)
Trials, 21, 1
TRIALS, 21(1):644. BMC
Trials
Trials, 21(1):644. BioMed Central Ltd
Trials, 21
Background Despite evidence of a quite large beneficial effect of endovascular treatment (EVT) for ischemic stroke caused by anterior circulation large vessel occlusion, many patients do not recover even after complete recanalization. To some extent,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2a9f1bf0ccc2a07f9748f1d3e7747d
https://research.utwente.nl/en/publications/92d4e46e-8870-4bd1-ae54-2a8fd8696630
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10
Workflow Intervals of Endovascular Acute Stroke Therapy During On- Versus Off-Hours The MR CLEAN Registry
Autor: Hinsenveld, W.H., Ridder, I.R. de, Oostenbrugge, R.J. van, Vos, J.A., Groot, A.E., Coutinho, J.M., Nijeholt, G.J.L.A., Boiten, J., Schonewille, W.J., Dippel, D.W.J., Lugt, A. van der, Majoie, C.B.L.M., Roos, Y.B.W.E.M., Zwam, W.H. van, Jansen, I.G.H., Mulder, M.J.H.L., Goldhoorn, R.J.B., Compagne, K.C.J., Kappelhof, M., Wermer, M.J.H., Walderveen, M.A.A. van, Staals, J., Hofmeijer, J., Martens, J.M., Roozenbeek, B., Emmer, B.J., Bruijn, S.F. de, Dijk, L.C. van, Worp, H.B. van der, R.H. lo, Dijk, E.J. van, Boogaarts, H.D., Kort, P.L.M. de, Peluso, J.J.P., Berg, J.S.P. van den, Hasselt, B.A.A.M. van, Aerden, L.A.M., Dallinga, R.J., Uyttenboogaart, M., Eshghi, O., Schreuder, T.H.C.M.L., Heijboer, R.J.J., Keizer, K., Yo, L.S.F., Hertog, H.M. den, Sturm, E.J.C., Sprengers, M.E.S., Jenniskens, S.F.M., Berg, R. van den, Yoo, A.J., Beenen, L.F.M., Postma, A.A., Roosendaal, S.D., Kallen, B.F.W. van der, Wijngaard, I.R. van den, Es, A.C.G.M. van, Bot, J., Doormaal, P.J. van, Flach, H.Z., Lingsma, H.F., Ghannouti, N. el, Sterrenberg, M., Puppels, C., Pellikaan, W., Sprengers, R., Elfrink, M., Meris, J. de, Vermeulen, T., Geerlings, A., Vemde, G. van, Simons, T., Rijswijk, C. van, Messchendorp, G., Bongenaar, H., Bodde, K., Kleijn, S., Lodico, J., Droste, H., Wollaert, M., Jeurrissen, D., Bos, E., Drabbe, Y., Aaldering, N., Zweedijk, B., Khalilzada, M., Venema, E., Chalos, V., Geuskens, R.R., Straaten, T. van, Ergezen, S., Harmsma, R.R.M., Muijres, D., Jong, A. de, Hinsenveld, W., Berkhemer, O.A., Boersc, A.M.M., Huguet, J., Groot, P.F.C., Mens, M.A., Kranendonk, K.R. van, Treurniet, K.M., Tolhuijsen, M.L., Alves, H., MR CLEAN Registry Investigators
Publikováno v: MR CLEAN Registry Investigators 2019, ' Workflow Intervals of Endovascular Acute Stroke Therapy During On-Versus Off-Hours The MR CLEAN Registry ', Stroke, vol. 50, no. 10, pp. 2842-2850 . https://doi.org/10.1161/STROKEAHA.119.025381
Stroke, 50(10), 2842-2850. LIPPINCOTT WILLIAMS & WILKINS
Stroke
Stroke, 50(10), 2842-2850. Lippincott Williams and Wilkins
Stroke, 50, 2842-2850
Stroke; a journal of cerebral circulation, 50(10), 2842-2850. Lippincott Williams and Wilkins
Stroke, 50(10), 2842-2850. Lippincott Williams & Wilkins
Stroke, 50, 10, pp. 2842-2850
Stroke, 50(10), 2842-2850
Background and Purpose— Endovascular treatment (EVT) of patients with acute ischemic stroke because of large vessel occlusion involves complicated logistics, which may cause a delay in treatment initiation during off-hours. This might lead to a wor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e01f0f42af296bc08a6587605d71299
https://doi.org/10.1161/strokeaha.119.025381
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