Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response

Autor: Patel, Anamika, Kumar, Sanjeev, Lai, Lilin, Chakravarthy, Chennareddy, Valanparambil, Rajesh, Reddy, Elluri Seetharami, Gottimukkala, Kamalvishnu, Bajpai, Prashant, Raju, Dinesh Ravindra, Edara, Venkata Viswanadh, Davis-Gardner, Meredith E., Linderman, Susanne, Dixit, Kritika, Sharma, Pragati, Mantus, Grace, Cheedarla, Narayanaiah, Verkerke, Hans P., Frank, Filipp, Neish, Andrew S., Roback, John D., Davis, Carl W., Wrammert, Jens, Ahmed, Rafi, Suthar, Mehul S., Sharma, Amit, Murali-Krishna, Kaja, Chandele, Anmol, Ortlund, Eric A.

Publikováno v: In Structure 6 July 2023 31(7):801-811

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Asymmetric and Non-Stoichiometric Recognition Results in Broad Protection Against Ebolaviruses by a Two-Antibody Cocktail

Autor: Jacob C. Milligan, Carl W. Davis, Saphire Lab/Xiaoying Yu, Philipp A. Ilinykh, Kai Huang, Peter Halfmann, Robert W. Cross, Viktoriya Borisevich, Krystle N. Agans, Joan B. Geisbert, Chakravarthy Chennareddy, Arthur J. Goff, Ashley E. Piper, Sean Hui, Kelly Shaffer, Tierra Buck, Megan L. Heinrich, Luis M. Branco, Ian Crozier, Michael R. Holbrook, Jens H. Kuhn, Yoshihiro Kawaoka, Pamela J. Glass, Alexander Bukreyev, Thomas W. Geisbert, Gabriella Worwa, Rafi Ahmed, Erica Ollmann Saphire

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17d09ea9051201388d9771e5e7c11f06
https://doi.org/10.2139/ssrn.3859645

Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection

Autor: Katherine J. L. Jackson, Chakravarthy Chennareddy, Arthur J. Goff, César G. Albariño, Sandra C. A. Nielsen, Erica Ollman Saphire, Anita K. McElroy, Aneesh K. Mehta, Carl W. Davis, Jessica Huang, Scott D. Boyd, Christina F. Spiropoulou, John Sidney, Pamela J. Glass, Alessandro Sette, Ali H. Ellebedy, Guy Cavet, Ian Crozier, Ashley E. Piper, Yvonne Leung, Tianwei Yu, Rafi Ahmed, Peter Halfmann, Yoshihiro Kawaoka

Publikováno v: Cell. 177:1566-1582.e17

Ebola virus (EBOV) remains a public health threat. We performed a longitudinal study of B cell responses to EBOV in four survivors of the 2014 West African outbreak. Infection induced lasting EBOV-specific immunoglobulin G (IgG) antibodies, but their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38332c7ce183107374182f4ca7c3435
https://doi.org/10.1016/j.cell.2019.04.036

Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.

Autor: Patel A; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA., Kumar S; ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, New Delhi, 110067, India., Lai L; Department of Pediatrics, Emory National Primate Center, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA., Chakravarthy C; Department of Microbiology and Immunology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA., Valanparambil R; Department of Microbiology and Immunology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA., Reddy ES; ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, New Delhi, 110067, India.; Kusuma School of Biological Sciences, Indian Institute of Technology, New Delhi, 110016, India., Gottimukkala K; ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, New Delhi, 110067, India., Bajpai P; ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, New Delhi, 110067, India., Raju DR; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA.; Georgia Tech, Atlanta, GA 30332, USA., Edara VV; Department of Pediatrics, Emory National Primate Center, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA., Davis-Gardner ME; Department of Pediatrics, Emory National Primate Center, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA., Linderman S; Department of Microbiology and Immunology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA., Dixit K; ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, New Delhi, 110067, India., Sharma P; ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, New Delhi, 110067, India., Mantus G; Department of Pediatrics, Emory National Primate Center, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA., Cheedarla N; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA., Verkerke HP; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02215, USA., Frank F; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA., Neish AS; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA., Roback JD; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA., Davis CW; Department of Microbiology and Immunology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA., Wrammert J; Department of Pediatrics, Emory National Primate Center, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA., Ahmed R; Department of Microbiology and Immunology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA., Suthar MS; Department of Pediatrics, Emory National Primate Center, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.; Department of Microbiology and Immunology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA., Sharma A; Structural Parasitology Group, International Center for Genetic Engineering and Biotechnology, New Delhi, 110067, India., Murali-Krishna K; ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, New Delhi, 110067, India.; Department of Pediatrics, Emory National Primate Center, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA.; Emory Vaccine Center, Emory University, Atlanta, GA 30322, USA., Chandele A; ICGEB-Emory Vaccine Center, International Center for Genetic Engineering and Biotechnology, New Delhi, 110067, India., Ortlund EA; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2022 Oct 24. Date of Electronic Publication: 2022 Oct 24.