Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Chaitanya K. Gavini"'
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Metabolic disorders such as obesity and type 2 diabetes (T2D) are increasingly prevalent worldwide, necessitating a deeper comprehension of their underlying mechanisms. However, translating findings from animal research to human patients remains chal
Externí odkaz:
https://doaj.org/article/cb1ab4da420945959ed89e255708a756
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The prevalence of peripheral neuropathy is high in diabetic and overweight populations. Chronic neuropathic pain, a symptom of peripheral neuropathy, is a major disabling symptom that leads to a poor quality of life. Glucose management for d
Externí odkaz:
https://doaj.org/article/3934267ecc3544699aa125f929bc933b
Autor:
Jomana Hatahet, Tyler M. Cook, Raiza R. Bonomo, Nadia Elshareif, Chaitanya K. Gavini, Chelsea R. White, Jason Jesse, Virginie Mansuy-Aubert, Gregory Aubert
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
More than 50% of patients with heart failure present with heart failure with preserved ejection fraction (HFpEF), and 80% of them are overweight or obese. In this study we developed an obesity associated pre-HFpEF mouse model and showed an improvemen
Externí odkaz:
https://doaj.org/article/2571248d5c164097bad987ebc3dcf512
Autor:
Chaitanya K. Gavini, Nadia Elshareif, Gregory Aubert, Anand V. Germanwala, Nigel A. Calcutt, Virginie Mansuy-Aubert
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Peripheral neuropathy is a common and progressive disorder in the elderly that interferes with daily activities. It is of importance to find efficient treatments to treat or delay this age-related neurodegeneration. Silencing macr
Externí odkaz:
https://doaj.org/article/91929b57cb8741daa50a9e577295d26d
Autor:
Tyler M. Cook, Chaitanya K. Gavini, Jason Jesse, Gregory Aubert, Emily Gornick, Raiza Bonomo, Laurent Gautron, Brian T. Layden, Virginie Mansuy-Aubert
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101350- (2021)
Objective: The vagus nerve provides a direct line of communication between the gut and the brain for proper regulation of energy balance and glucose homeostasis. Short-chain fatty acids (SCFAs) produced via gut microbiota fermentation of dietary fibe
Externí odkaz:
https://doaj.org/article/6021c23c9708486eb0d022d0dca9362c
Autor:
Chaitanya K. Gavini, Angie L. Bookout, Raiza Bonomo, Laurent Gautron, Syann Lee, Virginie Mansuy-Aubert
Publikováno v:
Cell Reports, Vol 25, Iss 2, Pp 271-277.e4 (2018)
Summary: Obesity is associated with many complications, including type 2 diabetes and painful neuropathy. There is no cure or prevention for obesity-induced pain, and the neurobiology underlying the onset of the disease is still obscure. In this stud
Externí odkaz:
https://doaj.org/article/da47ffdfcb4e4a60a63a84bba0bbe76a
Publikováno v:
Circulation. 144
Objective: We examined the effects of SGLT2 inhibition with Dapagliflozin (DAPA) on left ventricular ejection fraction (LVEF) and cardiomyocyte regeneration in mice after myocardial infraction (MI), a model for Heart Failure with reduced EF. Introduc
Autor:
Chaitanya K. Gavini, Nadia Elshareif, Gregory Aubert, Anand V. Germanwala, Nigel A. Calcutt, Virginie Mansuy-Aubert
Publikováno v:
Journal of neuroinflammation, vol 19, iss 1
Background Peripheral neuropathy is a common and progressive disorder in the elderly that interferes with daily activities. It is of importance to find efficient treatments to treat or delay this age-related neurodegeneration. Silencing macrophages b
Autor:
Anand V. Germanwala, Virginie Mansuy-Aubert, Gregory Aubert, Nadia Elshareif, Chaitanya K. Gavini, Nigel A. Calcutt
Peripheral neuropathy is a common and progressive disorder in the elderly that interferes with daily activities and increases the risk of injury. It is of importance to find efficient treatments to treat or delay this age-related neurodegeneration. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2c3ee5fa7690d13caca502b2ce93e1f
https://doi.org/10.1101/2021.09.22.461263
https://doi.org/10.1101/2021.09.22.461263
Autor:
Edward M. Campbell, Sarah Talley, Ben Chun, Chaitanya K. Gavini, Tyler Cook, Jomana Hatahet, Pete Kekenes-Huskey, Virginie Mansuy-Aubert, Raiza Bonomo, Gregory Aubert
Obesity is a current epidemic, affecting millions of individuals worldwide. Chronic obesity is characterized by a low-grade systemic inflammation besides not being a classic inflammatory disease. Many studies have tried to identify inflammatory insul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9b01f55b1642a07c2f7e80bc6e4e61e
https://doi.org/10.1101/2021.09.22.461384
https://doi.org/10.1101/2021.09.22.461384