Cross-sectional and Test-Retest Characterization of PET with [18F]FP-(+)-DTBZ for β Cell Mass Estimates in Diabetes

Autor: Rudolph L. Leibel, Paul L. Harris, Robin Goland, Matthew J. Freeby, Antonella Maffei, Masanori Ichise, Patricia Kringas, Chaitan Divgi

Publikováno v: Molecular imaging and biology (2015). doi:10.1007/s11307-015-0888-7
info:cnr-pdr/source/autori:Freeby MJ, Kringas P, Goland RS, Leibel RL, Maffei A, Divgi C, Ichise M, Harris PE./titolo:Cross-sectional and Test-Retest Characterization of PET with [18F]FP-(+)-DTBZ for ? Cell Mass Estimates in Diabetes./doi:10.1007%2Fs11307-015-0888-7/rivista:Molecular imaging and biology/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume
Molecular Imaging and Biology

Purpose The vesicular monoamine transporter, type 2 (VMAT2) is expressed by insulin producing β cells and was evaluated as a biomarker of β cell mass (BCM) by positron emission tomography (PET) with [18F]fluoropropyl-dihydrotetrabenazine ([18F]FP-(

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