Zobrazeno 1 - 10
of 2 762
pro vyhledávání: '"Chaikuad A"'
Autor:
Alexander Strubel, Philipp Münick, Oliver Hartmann, Apirat Chaikuad, Birgit Dreier, Jonas V. Schaefer, Jakob Gebel, Christian Osterburg, Marcel Tuppi, Birgit Schäfer, Viktoria Buck, Mathias Rosenfeldt, Stefan Knapp, Andreas Plückthun, Markus E. Diefenbacher, Volker Dötsch
Publikováno v:
Cell Death and Disease, Vol 14, Iss 10, Pp 1-12 (2023)
Abstract The two p53 homologues p63 and p73 regulate transcriptional programs in epithelial tissues and several cell types in these tissues express both proteins. All members of the p53 family form tetramers in their active state through a dedicated
Externí odkaz:
https://doaj.org/article/af967dcb30b740eda6294164fd218dc4
Autor:
Frances M. Bashore, Ariana B. Marquez, Apirat Chaikuad, Stefanie Howell, Andrea S. Dunn, Alvaro A. Beltran, Jeffery L. Smith, David H. Drewry, Adriana S. Beltran, Alison D. Axtman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Tau tubulin kinase 1 and 2 (TTBK1/2) are highly homologous kinases that are expressed and mediate disease-relevant pathways predominantly in the brain. Distinct roles for TTBK1 and TTBK2 have been delineated. While efforts have been devoted
Externí odkaz:
https://doaj.org/article/f01d040d3ceb453db5721ee57c431eb7
Autor:
Hasyeoui, Mohamed, Lassagne, Frédéric, Erb, William, Nael, Manal, Elokely, Khaled M., Chaikuad, Apirat, Knapp, Stefan, Jorda, Adrian, Vallés, Soraya L., Quissac, Emie, Verreault, Maïté, Robert, Thomas, Bach, Stéphane, Samarat, Ali, Mongin, Florence
Publikováno v:
In Bioorganic Chemistry May 2023 134
Autor:
Arora, Rohit, Linders, Joannes T.M., Aci-Sèche, Samia, Verheyen, Thomas, Van Heerde, Erika, Brehmer, Dirk, Chaikuad, Apirat, Knapp, Stefan, Bonnet, Pascal
Publikováno v:
In European Journal of Medicinal Chemistry 15 March 2023 250
Publikováno v:
IUCrJ, Vol 9, Iss 6, Pp 720-727 (2022)
Tripartite motif (TRIM) proteins constitute one of the largest subfamilies of the RING-type E3 ubiquitin ligases that play a role in diverse processes from homeostasis and immune response to viral restriction. While TRIM proteins typically harbor an
Externí odkaz:
https://doaj.org/article/0aee4b6a847f47998912754e7b217eae
Autor:
Arifi, Silvia, Zaienne, Daniel, Heering, Jan, Wein, Thomas, Zhubi, Rezart, Chaikuad, Apirat, Knapp, Stefan, Marschner, Julian A., Merk, Daniel
Publikováno v:
In Bioorganic Chemistry December 2022 129
Publikováno v:
Open Biology, Vol 13, Iss 5 (2023)
FUBP-interacting repressor (FIR) is a suppressor of transcription of the proto-oncogene MYC. FIR binds to the far upstream element (FUSE) of the MYC promoter. Competition of FIR with FUSE-binding protein 1 (FUBP1) is a key mechanism of MYC transcript
Externí odkaz:
https://doaj.org/article/7ea26a6a1ce140d785b724457158db4a
Autor:
Zeinyeh, Wael, Esvan, Yannick J., Josselin, Béatrice, Defois, Mathilde, Baratte, Blandine, Knapp, Stefan, Chaikuad, Apirat, Anizon, Fabrice, Giraud, Francis, Ruchaud, Sandrine, Moreau, Pascale
Publikováno v:
In European Journal of Medicinal Chemistry 5 June 2022 236
Autor:
Cullati, Sierra N., Chaikuad, Apirat, Chen, Jun-Song, Gebel, Jakob, Tesmer, Laura, Zhubi, Rezart, Navarrete-Perea, Jose, Guillen, Rodrigo X., Gygi, Steven P., Hummer, Gerhard, Dötsch, Volker, Knapp, Stefan, Gould, Kathleen L.
Publikováno v:
In Molecular Cell 2 June 2022 82(11):2006-2020
Autor:
Willems, Sabine, Gellrich, Leonie, Chaikuad, Apirat, Kluge, Stefan, Werz, Oliver, Heering, Jan, Knapp, Stefan, Lorkowski, Stefan, Schubert-Zsilavecz, Manfred, Merk, Daniel
Publikováno v:
In Cell Chemical Biology 21 October 2021 28(10):1489-1500