Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Chaidong Cho"'
Publikováno v:
Cancer. 70:1536-1540
BACKGROUND Iproplatin (cis-dichloro-transdihydroxybis-isopropylamine platinum IV; CHIP) is a second generation cisplatin derivative that was developed to retain the antineoplastic effect of cisplatin with fewer toxic effects. Early clinical studies s
Autor:
Robin J Flynn, Chaidong Cho
Publikováno v:
Laboratory Medicine. 21:823-826
To investigate the enzyme induction effects of antiepileptic drugs (AEDs) on laboratory tests in a group of elderly males, a panel of liver function tests was run on 99 patients receiving AEDs and the results were compared with 102 age-matched patien
Publikováno v:
Journal of clinical pharmacology. 30(4)
Blood and urine samples were collected simultaneously with measurements of pulmonary function at 2-hour intervals for 8 hours after oral administration of short-acting (SAT) and long-acting theophylline (LAT) preparations in 15 patients with stable c
Publikováno v:
Gastroenterology. 78:100-107
The hypothesis that propylthiouracil (PTU)-induced hypothyroidism (HT) has a protective effect against the hepatic toxicity of acetaminophen (Tylenol or Paracetamol) was tested in a rat model. Toxic doses of acetaminophen (AAP) were administered to r
Publikováno v:
Journal of Toxicology and Environmental Health. 15:477-484
The protective effect of 16, 16-dimethylprostaglandin E2 (dm-PGE2) against acetaminophen-induced hepatotoxicity was determined in the rat. The dm-PGE2 was administered at two dose levels both before and after acetaminophen administration. The hepatot
Publikováno v:
Gastroenterology. 87:941-947
Whipple's disease is often accompanied by a long, preintestinal phase of vague symptoms, such as weight loss, fever, and migratory arthralgia, which may delay diagnosis and proper treatment. We report a patient who presented with sarcoidlike granulom
Publikováno v:
Journal of Toxicology and Environmental Health. 12:143-158
This present study was designed to assess the role of metabolic and pharmacokinetic factors in the lower susceptibility of female rats compared to male rats to xenobiotics metabolized by the cytochrome P-450-dependent mixed-function oxidase (MFO) sys
Publikováno v:
Toxicology. 11:1-4
Summary Oral administration of β-glycerophosphate lowers the lithogenic index in patients with cholesterol gallstones and is considered to have potential for dissolving them. A high dose of β-glycerphosphate was fed to primates (Squirrel monkeys) f
Publikováno v:
Gastroenterology. 83:121-126
Alpha-chain disease with involvement of small intestine resulting in characteristic villus atrophy and malabsorption has not been reported in this country. We studied a 57-yr-old male who presented with a polypoid tumor of the hepatic flexure of the
Publikováno v:
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. 76(1)
This study was designed to investigate the protective effect of PTU pretreatment against acetaminophen hepatotoxicity in rats whose hepatic GSH had been depleted by prior diethylmaleate (DEM) administration. A single injection of DEM depleted hepatic