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of 7
pro vyhledávání: '"Chahat Mehra"'
Autor:
Chahat Mehra, Lena Pernas
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTA microbe and its host are in constant communication. An emerging platform for direct communication is the membrane contact sites that form between several pathogens and host organelles. Here, we review our progress on the molecular mechanism
Externí odkaz:
https://doaj.org/article/5a4d64def9be4c12b98a6012208ae40d
Autor:
Chahat Mehra, Ji-Hyun Chung, Yi He, Mónica Lara-Márquez, Marie-Anne Goyette, Nadia Boufaied, Véronique Barrès, Véronique Ouellet, Karl-Phillippe Guérard, Carine Delliaux, Fred Saad, Jacques Lapointe, Jean-François Côté, David P. Labbé, Nathalie Lamarche-Vane
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Mehra et al. investigate the role of CdGAP in early biochemical recurrence and bone metastasis in prostate cancer. The authors find that knocking down CdGAP leads to reduced cell motility, invasion and proliferation in PC-3 and 22Rv1 cells while orth
Externí odkaz:
https://doaj.org/article/90e48f7b139747d6ba6e98b737476318
Publikováno v:
Current Opinion in MIcrobiology
Curr Opin Microbiol
Curr Opin Microbiol
Invading microbes occupy the host cytosol and take up nutrients on which host organelles are also dependent. Thus, host organelles are poised to interact with intracellular microbes. Despite the essential role of host mitochondria in cellular metabol
Autor:
Fred Saad, Jacques Lapointe, Yi He, Mónica Lara-Márquez, Nathalie Lamarche-Vane, David P. Labbé, Jean-François Côté, Ji-Hyun Chung, Nadia Boufaied, Karl-Phillippe Guérard, Chahat Mehra, Marie-Anne Goyette, Carine Delliaux, Veronique Ouellet, Véronique Barrès
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology
Communications Biology
High mortality of prostate cancer patients is primarily due to metastasis. Understanding the mechanisms controlling metastatic processes remains essential to develop novel therapies designed to prevent the progression from localized disease to metast
Autor:
Chahat Mehra, Lena Pernas
Publikováno v:
Dev Cell
Summary Mechanisms by which cells remove damaged mitochondria extracellularly are unclear. Recent work by Jiao and colleagues in Cell shows that migrating cells expel dysfunctional mitochondria in membrane-bound structures called migrasomes to mainta
Autor:
Vivekanand Kumar, Raman Khurana, Nilotpal Barooah, Naveen Kumar, Achikanath C. Bhasikuttan, Chahat Mehra, Suchandra Chatterjee, Aarti S. Kakatkar, Ravisha Gala, Jyotirmayee Mohanty
Publikováno v:
Chemical Communications. 55:14275-14278
The amelioration of antibacterial efficacy along with the reduced minimum inhibitory concentration (MIC) of sanguinarine (SGR) drug have been demonstrated through the uptake of SGR by p-sulfonatocalix[6]arene functionalized silver nanoparticles. The
Autor:
Xianhe Li, Julian Straub, Tânia Catarina Medeiros, Chahat Mehra, Fabian den Brave, Esra Peker, Ilian Atanassov, Katharina Stillger, Jonas Benjamin Michaelis, Emma Burbridge, Colin Adrain, Christian Münch, Jan Riemer, Thomas Becker, Lena F. Pernas
Publikováno v:
Science
Mitochondria shed their SPOTs Outer mitochondrial membrane (OMM) function is essential for cellular health. How mitochondria respond to naturally occurring OMM stress is unknown. Li et al . show that, upon infection with the human parasite Toxoplasma