Missense mutations in inositol 1,4,5-trisphosphate receptor type 3 result in leaky Ca ²⁺ channels and activation of store-operated Ca ²⁺ entry.

Autor: Terry LE; Department of Pharmacology and Physiology, University of Rochester, Rochester, NY 14642, USA., Arige V; Department of Pharmacology and Physiology, University of Rochester, Rochester, NY 14642, USA., Neumann J; KU Leuven, Department of Microbiology and Immunology, Leuven, Belgium., Wahl AM; Department of Pharmacology and Physiology, University of Rochester, Rochester, NY 14642, USA., Knebel TR; Department of Pharmacology and Physiology, University of Rochester, Rochester, NY 14642, USA., Chaffer JW; Department of Pharmacology and Physiology, University of Rochester, Rochester, NY 14642, USA., Malik S; Department of Pharmacology and Physiology, University of Rochester, Rochester, NY 14642, USA., Liston A; KU Leuven, Department of Microbiology and Immunology, Leuven, Belgium., Humblet-Baron S; KU Leuven, Department of Microbiology and Immunology, Leuven, Belgium., Bultynck G; KU Leuven, Laboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, Leuven, Belgium., Yule DI; Department of Pharmacology and Physiology, University of Rochester, Rochester, NY 14642, USA.

Publikováno v: IScience [iScience] 2022 Nov 07; Vol. 25 (12), pp. 105523. Date of Electronic Publication: 2022 Nov 07 (Print Publication: 2022).