Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Chaeuk Im"'
Autor:
Chaeuk Im
Publikováno v:
Archives of Pharmacal Research. 39:1635-1643
Aurora A kinase is involved in the inactivation of apoptosis leading to ovarian, breast, colon, and pancreatic cancers. Inhibitors of Aurora A kinase promote aberrant mitosis resulting in arrest at a pseudo G1 state to induce mitotic catastrophe, ult
Autor:
Yu Jin Hwang1, Chaeuk Im1 chaeukim@cau.ac.kr
Publikováno v:
Bulletin of the Korean Chemical Society. 2014, Vol. 35 Issue 7, p2065-2071. 7p.
Publikováno v:
Archives of Pharmacal Research. 26:270-274
A series of new 3-alkyl-1-(1-methyl-2-phenylethyl)ureas related to ceramide was synthesized and evaluated for their in vitro cytotoxic activity against five human tumor cell lines. The urea analogue (2b) of B13 showed comparable or slightly more pote
Publikováno v:
Archives of Pharmacal Research. 20:647-651
The 6,6-dibromopenam6 was treated with CH(3)MgBr and carbaldehyde5 to afford the 6-bromo-6-(1-hydroxy-1-methyl)penicillanate7, which was reacted with acetic anhydride to give acetoxy compound8. The deacetobromination of8 with zinc and acetic acid gav
Publikováno v:
Archives of Pharmacal Research. 20:652-655
The(1)H-NMR signals of 2-cephems and 3-cephems have been assigned and the Nuclear Overhauser Effect (NOE) study of these compounds was undertaken.
Autor:
Chaeuk Im, Hak Rim Kim, Xiang Mei Yan, Wan Kyun Whang, Min Jae Joo, Sang Soo Sim, Uy Dong Sohn, Inkyeom Kim, Jae Chun Lim, Seok-Yong Lee
Publikováno v:
Archives of pharmacal research. 34(9)
The mechanism of the protective effect of quercetin-3-O-β-D-glucuronopyranoside (QGC) from the leaves of Rumex aqauticus on indomethacin (IND, a representative NSAID)-induced gastric damage in rats was investigated. Pre-treatment with QGC significan
Publikováno v:
ChemInform. 30
Autor:
Inkyeom Kim, Sun Young Park, Ji Hoon Jeong, Byung-Chul Choi, Sang Soo Sim, Xiangmei Yan, Uy Dong Sohn, Yih Hsiu Sun, Hyun Soo Kwak, Mina Kim, Chaeuk Im, Jae Ho Shim, Young Sil Min
We have shown that myosin light chain kinase (MLCK) was required for the off-contraction in response to the electrical field stimulation (EFS) of feline esophageal smooth muscle. In this study, we investigated whether protein kinase C (PKC) may requi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f5b7d6c868b6e32d514810e2c7b558
https://europepmc.org/articles/PMC2835980/
https://europepmc.org/articles/PMC2835980/
Publikováno v:
The Korean journal of physiologypharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. 13(1)
Three dimensional quantitative structure activity relationship between diazabicyclo[4.2.0]octanes and nicotinic acetylcholine receptor (halpha4beta2 and halpha3beta4) agonists was studied using comparative molecular field analysis (CoMFA) and compara
Publikováno v:
Archives of pharmacal research. 30(5)
A series of D-erythro ceramide analogues, N-(2S, 3R, 4E)-1, 3-dihydroxy-5-phenyl pent-4-en-2-yl alkyl sulfonamides, were synthesized and evaluated for their in vitro cytotoxic activities against five human tumor cell lines. The aromatic sulfon amido