Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Chaetocin"'
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 13, Iss 6, Pp 268-276 (2023)
Objective: To evaluate the effect of chaetocin on pyroptosis of gastric cancer cells and its underlying mechanisms. Methods: The proliferation of gastric cancer cells was detected by trypan blue staining. Flow cytometry and Hoechst/propidium iodide d
Externí odkaz:
https://doaj.org/article/bccf590c054746089f29e5340658f41a
Autor:
Tsung-Chieh Lin
Publikováno v:
Cells, Vol 12, Iss 12, p 1628 (2023)
ATP-dependent RNA helicase DDX3X, also known as DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X), is critical for RNA metabolism, and emerging evidence implicates ATP-dependent RNA helicase DDX3X’s participation in various cellular proces
Externí odkaz:
https://doaj.org/article/df836d2530fd41c1a5d3a45ebed1a660
Autor:
Mengjia Qian, Xin Cao
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 2, Pp n/a-n/a (2022)
Abstract Lung large cell carcinoma is a common type of lung cancer with poor prognosis. Although targeted drugs have achieved enormous success in treating non‐small‐cell lung carcinoma (NSCLC), new chemotherapy is needed since the emerged drug re
Externí odkaz:
https://doaj.org/article/42503e46d09643328bf0f102ddc9e429
Autor:
Sadia Samer, Muhammad Shoaib Arif, Leila Bertoni Giron, Jean Paulo Lopes Zukurov, James Hunter, Bruna Teresa Santillo, Gislene Namiyama, Juliana Galinskas, Shirley Vasconcelos Komninakis, Telma Miyuki Oshiro, Maria Cecilia Sucupira, Luiz Mario Janini, Ricardo Sobhie Diaz
Publikováno v:
Brazilian Journal of Infectious Diseases, Vol 24, Iss 2, Pp 150-159 (2020)
Background: Latent HIV-1 is a major hurdle in obtaining HIV-1 sustained virological remission (SVR). Here we explored histone deacetylation inhibition property of nicotinamide (NAM; n = 17) for the first time in comparison to a combination of methylt
Externí odkaz:
https://doaj.org/article/dc4c4bab15404e79a03bd50da2bb1f03
Akademický článek
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Autor:
Pil-Soo Jeong, Hae-Jun Yang, Soo-Hyun Park, Min Ah Gwon, Ye Eun Joo, Min Ju Kim, Hyo-Gu Kang, Sanghoon Lee, Young-Ho Park, Bong-Seok Song, Sun-Uk Kim, Deog-Bon Koo, Bo-Woong Sim
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Developmental defects in somatic cell nuclear transfer (SCNT) embryos are principally attributable to incomplete epigenetic reprogramming. Small-molecule inhibitors such as histone methyltransferase inhibitors (HMTi) and histone deacetylase inhibitor
Externí odkaz:
https://doaj.org/article/cc048abf3d2e4f5d987ef25c017dd396
Autor:
Huihui Wang, Chuangyu Wen, Siyu Chen, Weiqian Li, Qiyuan Qin, Lu He, Fang Wang, Junxiong Chen, Weibiao Ye, Wende Li, Junsheng Peng, Xiangling Yang, Huanliang Liu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
There is an urgent need for novel agents for colorectal cancer (CRC) due to the increasing number of cases and drug-resistance related to current treatments. In this study, we aim to uncover the potential of chaetocin, a natural product, as a chemoth
Externí odkaz:
https://doaj.org/article/cbd34d805ee14d38897da94f6de55902
Autor:
Ignacio Campillo-Marcos, Eva Monte-Serrano, Elena Navarro-Carrasco, Raúl García-González, Pedro A. Lazo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
BackgroundChromatin is dynamically remodeled to adapt to all DNA-related processes, including DNA damage responses (DDR). This adaptation requires DNA and histone epigenetic modifications, which are mediated by several types of enzymes; among them ar
Externí odkaz:
https://doaj.org/article/b6ecc03d978141a6964175a15dcf37b4
Autor:
Zhao Yang, Haifeng Wang, Nan Zhang, Tianying Xing, Wei Zhang, Guoqing Wang, Chong Li, Changyuan Yu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Bladder cancer stem cells (BCSCs) have the abilities of self-renewal, differentiation, and metastasis; confer drug resistance; and exhibit high tumorigenicity. We previously identified that the KMT1A–GATA3–STAT3 axis drives the self-renewal of BC
Externí odkaz:
https://doaj.org/article/79095203532e46da9e5e8cf9f781fc1c
Akademický článek
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