Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chaela S. Presley"'
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 1118-1123 (2016)
The ACTOne cannabinoid receptor 1 functional system is comprised of transfected HEK cells with the parental cyclic nucleotide gated channel (CNG) co-transfected with cannabinoid receptor 1 (CB1). The ACTOne CB1 cell line was evaluated for cAMP driven
Externí odkaz:
https://doaj.org/article/42114caf221e4c6ea720631b0746466f
Autor:
David A. Tipton, Chaela S. Presley, Ammaar H. Abidi, Suni M. Mustafa, Bob M. Moore, Mustafa Kh. Dabbous
Publikováno v:
Archives of oral biology. 87
Objectives Approximately 65 million adults in the US have periodontitis, causing tooth loss and decreased quality of life. Cannabinoids modulate immune responses, and endocannabinoids are prevalent during oral cavity inflammation. Targets for interve
Autor:
Chaela S. Presley, Jessica Ferrell, Nobel Del Mar, Yunping Deng, Lauren D'Surney, Steven N. Gurley, Natalie H. Guley, Wei Bu, Scott A. Heldt, Andrea J. Elberger, Anton Reiner, Marcia G. Honig, Bob M. Moore, Joshua T. Rogers
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 16, Iss 1, Pp 758-787 (2014)
Volume 16
Issue 1
Pages 758-787
International Journal of Molecular Sciences, Vol 16, Iss 1, Pp 758-787 (2014)
Volume 16
Issue 1
Pages 758-787
We have developed a focal blast model of closed-head mild traumatic brain injury (TBI) in mice. As true for individuals that have experienced mild TBI, mice subjected to 50–60 psi blast show motor, visual and emotional deficits, diffuse axonal inju
Autor:
Charles R. Yates, Jena J. Steinle, Jayaprakash Pagadala, Chaela S. Presley, Kimberly Williams-Guy, Duane D. Miller, Hui He
Publikováno v:
Journal of Chromatography B. :86-91
Ocular administration of the beta (β)-adrenergic receptor agonist JP-49b prevents retinopathy-like damage in a preclinical rat model of diabetes. Importantly, JP-49b did not induce characteristic β-adrenergic agonist-related side effects (e.g., lef
Autor:
Suni M. Mustafa, Bob M. Moore, Bernd Meibohm, Ammaar H. Abidi, Chaela S. Presley, Satyendra Suryawanshi
Publikováno v:
Pharmacology Research & Perspectives
Cannabinoid receptor 2 agonists and inverse agonists are emerging as new therapeutic options for a spectrum of autoimmune-related disease. Of particular interest, is the ability of CB2 ligands to regulate microglia function in neurodegenerative disea
Publikováno v:
Analytical biochemistry. 498
In vitro cannabinoid pharmacology has evolved over time from simple receptor binding to include [ 35 S]GTPγ, β-arrestin, and cAMP assays. Each assay has benefits and drawbacks; however, no single functional system has been used for high-throughput
Publikováno v:
Bioorganicmedicinal chemistry. 23(17)
Cannabinoid receptor 2 (CB2) selective agonists and inverse agonists possess significant potential as therapeutic agents for regulating inflammation and immune function. Although CB2 agonists have received the greatest attention, it is emerging that
Autor:
Charles R. Yates, Richard J. Bloomer, Chaela S. Presley, Kelley G. Hammond, Brian K. Schilling
Publikováno v:
BMC Pharmacology & Toxicology
Background 1,3-dimethylamylamine (DMAA) has been a component of dietary supplements and is also used within "party pills," often in conjunction with alcohol and other drugs. Ingestion of higher than recommended doses results in untoward effects inclu
Publikováno v:
Analytical Biochemistry. 501:47
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 41(11)
KZ-41, a quinic acid derivative, significantly reduces mortality in a murine model of hematopoietic acute radiation syndrome. The purpose of this study was to evaluate the systemic pharmacokinetics, elimination, and oral bioavailability of KZ-41 in r