Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Chae‐Myeong Ha"'
Autor:
Chae‐Myeong Ha, Sayan Bakshi, Manoja K. Brahma, Luke A. Potter, Samuel F. Chang, Zhihuan Sun, Gloria A. Benavides, Lihao He, Prachi Umbarkar, Luyun Zou, Samuel Curfman, Sini Sunny, Andrew J. Paterson, Namakkal‐Soorappan Rajasekaran, Jarrod W. Barnes, Jianhua Zhang, Hind Lal, Min Xie, Victor M. Darley‐Usmar, John C. Chatham, Adam R. Wende
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 19 (2023)
Background Lifestyle and metabolic diseases influence the severity and pathogenesis of cardiovascular disease through numerous mechanisms, including regulation via posttranslational modifications. A specific posttranslational modification, the additi
Externí odkaz:
https://doaj.org/article/be156b0fab8e4ad2aa747f5829ccfd51
Autor:
Christian Riehle, Jan-Thorben Sieweke, Sayan Bakshi, Chae-Myeong Ha, Nanna Louise Junker Udesen, Ole K. Møller-Helgestad, Natali Froese, Hanne Berg Ravn, Heike Bähre, Robert Geffers, Roland Seifert, Jacob E. Møller, Adam R. Wende, Johann Bauersachs, Andreas Schäfer
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundCardiogenic shock (CS) alters whole body metabolism and circulating biomarkers serve as prognostic markers in CS patients. Percutaneous ventricular assist devices (pVADs) unload the left ventricle by actively ejecting blood into the aorta.
Externí odkaz:
https://doaj.org/article/e8343c6376ea4bfdae12bd413e98bf54
Autor:
Manoja K. Brahma, Chae‐Myeong Ha, Mark E. Pepin, Sobuj Mia, Zhihuan Sun, John C. Chatham, Kirk M. Habegger, Evan Dale Abel, Andrew J. Paterson, Martin E. Young, Adam R. Wende
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 15 (2020)
Background Perturbations in myocardial substrate utilization have been proposed to contribute to the pathogenesis of cardiac dysfunction in diabetic subjects. The failing heart in nondiabetics tends to decrease reliance on fatty acid and glucose oxid
Externí odkaz:
https://doaj.org/article/0690fe8d35c040cc85c04ea9e3298c31
Autor:
Sungmi Park, Jae-Han Jeon, Byong-Keol Min, Chae-Myeong Ha, Themis Thoudam, Bo-Yoon Park, In-Kyu Lee
Publikováno v:
Diabetes & Metabolism Journal, Vol 42, Iss 4, Pp 270-281 (2018)
Mitochondrial dysfunction is a hallmark of metabolic diseases such as obesity, type 2 diabetes mellitus, neurodegenerative diseases, and cancers. Dysfunction occurs in part because of altered regulation of the mitochondrial pyruvate dehydrogenase com
Externí odkaz:
https://doaj.org/article/0a7d53f5a1374c66b75be2162ad29613
Autor:
Byong-Keol Min, Sungmi Park, Hyeon-Ji Kang, Dong Wook Kim, Hye Jin Ham, Chae-Myeong Ha, Byung-Jun Choi, Jung Yi Lee, Chang Joo Oh, Eun Kyung Yoo, Hui Eon Kim, Byung-Gyu Kim, Jae-Han Jeon, Do Young Hyeon, Daehee Hwang, Yong-Hoon Kim, Chul-Ho Lee, Taeho Lee, Jung-whan Kim, Yeon-Kyung Choi, Keun-Gyu Park, Ajay Chawla, Jongsoon Lee, Robert A. Harris, In-Kyu Lee
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Metabolic reprogramming during macrophage polarization supports the effector functions of these cells in health and disease. Here, we demonstrate that pyruvate dehydrogenase kinase (PDK), which inhibits the pyruvate dehydrogenase-mediated conversion
Externí odkaz:
https://doaj.org/article/3e6ebf55ddb64a868809df4fe880a698
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Inflammation is considered to be one of the most critical factors involved in the development of complex metabolic diseases such as type 2 diabetes, cancer, and cardiovascular disease. A few decades ago, the discovery of mitochondria-associated endop
Externí odkaz:
https://doaj.org/article/e2b2a04fda4a429d9511d1833232c270
Publikováno v:
American Journal of Physiology: Heart & Circulatory Physiology; Oct2023, Vol. 325 Issue 4, p1-16, 16p
Publikováno v:
Circulation Research. 131
Cardiovascular diseases, including ischemic heart failure (IHF), are the leading cause of mortality worldwide; furthermore, African Americans (AA) have 30% higher mortality than Caucasian Americans (CA). Our recent study correlates racial differences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::190f565f6afa84057dc9651f27bb1c1c
https://doi.org/10.1161/res.131.suppl_1.p3099
https://doi.org/10.1161/res.131.suppl_1.p3099
Autor:
Selwyn M. Vickers, Mark E Pepin, Salpy V. Pamboukian, Joseph Barchue, Chae-Myeong Ha, Ayman Haj Asaad, Sayan Bakshi, Steven M. Pogwizd, Bertha Hidalgo, Adam R. Wende, Luke A Potter
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology
Am J Physiol Heart Circ Physiol
Am J Physiol Heart Circ Physiol
Heart failure (HF) is a multifactorial syndrome that remains a leading cause of worldwide morbidity. Despite its high prevalence, only half of patients with HF respond to guideline-directed medical management, prompting therapeutic efforts to confron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e451096337a136760f14eccfb24b465f
http://europepmc.org/articles/PMC8163657
http://europepmc.org/articles/PMC8163657
Autor:
Manoja K. Brahma, Chase A. Andrizzi, Renata O. Pereira, E. Dale Abel, Wayne E. Bradley, Oleh Khalimonchuk, John C. Schell, Ariel Contreras-Ferrat, Curtis D. Olsen, Adam R. Wende, Chae-Myeong Ha, Li Wang, Sheldon E. Litwin, Hansjörg Schwertz, Louis J. Dell'Italia, Joseph Tuinei, Wolfgang H. Dillmann, Mark E Pepin
Publikováno v:
Diabetes
Cardiac glucose uptake and oxidation are reduced in diabetes despite hyperglycemia. Mitochondrial dysfunction contributes to heart failure in diabetes. It is unclear whether these changes are adaptive or maladaptive. To directly evaluate the relation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43575547266556dae6449026c899cfd0
https://doi.org/10.2337/db19-1057
https://doi.org/10.2337/db19-1057