Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Chad W Euler"'
Autor:
Rachael E. Workman, Marie J. Stoltzfus, Nicholas C. Keith, Chad W. Euler, Joseph Bondy-Denomy, Joshua W. Modell
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113849- (2024)
Summary: CRISPR-Cas immune systems provide bacteria with adaptive immunity against bacteriophages, but they are often transcriptionally repressed to mitigate auto-immunity. In some cases, CRISPR-Cas expression increases in response to a phage infecti
Externí odkaz:
https://doaj.org/article/8f1d1d1e943a4010b6fec27b0be2675a
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Most skin infections, including those complicating burns, are polymicrobial involving multiple causative bacteria. Add to this the fact that many of these organisms may be antibiotic-resistant, and a simple skin lesion or burn could soon become life-
Externí odkaz:
https://doaj.org/article/ffec277bf6ac4bd69745dd271bcae0a8
Autor:
Chad W. Euler, Assaf Raz, Anaise Hernandez, Anna Serrano, Siyue Xu, Martin Andersson, Geng Zou, Yue Zhang, Vincent A. Fischetti, Jinquan Li
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Klebsiella pneumoniae and Pseudomonas aeruginosa are two leading causes of burn and wound infections, pneumonia, urinary tract infections, and more severe invasive diseases, which are often multidrug resistant (MDR) or extensively drug resistant. Due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74e06c96ed86f583fcd3c12e7e37c7ab
https://doi.org/10.1128/aac.01519-22
https://doi.org/10.1128/aac.01519-22
Autor:
Chandrabali Ghose, Chad W. Euler
Publikováno v:
Antibiotics, Vol 9, Iss 2, p 74 (2020)
Antibiotics have had a profound impact on human society by enabling the eradication of otherwise deadly infections. Unfortunately, antibiotic use and overuse has led to the rapid spread of acquired antibiotic resistance, creating a major threat to pu
Externí odkaz:
https://doaj.org/article/3cb5e41cc486435b96a22097431864aa
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006726 (2018)
A fundamental question in human susceptibility to bacterial infections is to what extent variability is a function of differences in the pathogen species or in individual humans. To focus on the pathogen species, we compared in the same individual th
Externí odkaz:
https://doaj.org/article/04d54df2f7e34177831ff53ea0d92cbb
Autor:
Pascal Maguin, Albina Kozlova, Jessica Fyodorova, Edmondo Campisi, Andrew Varble, Jakob T. Rostøl, Vincent A. Fischetti, Chad W. Euler, Luciano A. Marraffini
Publikováno v:
Nature Microbiology. 6:1516-1525
CRISPR loci are composed of short DNA repeats separated by sequences, known as spacers, that match the genomes of invaders such as phages and plasmids. Spacers are transcribed and processed to generate RNA guides used by CRISPR-associated nucleases t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ffbdfef61557bc99cf303e3051e7586
https://doi.org/10.1038/s41564-021-00996-8
https://doi.org/10.1038/s41564-021-00996-8
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169180 (2017)
Streptococcus suis infects pigs worldwide and may be zoonotically transmitted to humans with a mortality rate of up to 20%. S. suis has been shown to develop in vitro resistance to the two leading drugs of choice, penicillin and gentamicin. Because o
Externí odkaz:
https://doaj.org/article/584db489c53d44668c9e774fe48e82ea
Autor:
Chad W Euler, Barbara Juncosa, Patricia A Ryan, Douglas R Deutsch, W Michael McShan, Vincent A Fischetti
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146408 (2016)
Streptococcus pyogenes is a human commensal and a bacterial pathogen responsible for a wide variety of human diseases differing in symptoms, severity, and tissue tropism. The completed genome sequences of >37 strains of S. pyogenes, representing dive
Externí odkaz:
https://doaj.org/article/690164f67df54a7d895280ef980fba45
Autor:
Maria Pardos de la Gandara, Christopher E Cheleuitte-Nieves, Leslie Lynn Diaz, Chad W. Euler, Alejandra Gonzalez, Winrich A. Freiwald, Hermínia M de Lencastre, Alexander Tomasz
Publikováno v:
Comparative Medicine. 70:335-347
Lytic enzymes are novel antimicrobial agents that degrade bacterial cell walls, resulting in cell rupture and death. We tested one enzyme, the bacteriocin lysostaphin, for treatment of nonhuman primates (Macaca mulatta) with persistent methicillinres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::777a22fbde23e9580b075528dd0efd2e
https://doi.org/10.30802/aalas-cm-19-000102
https://doi.org/10.30802/aalas-cm-19-000102
Publikováno v:
Future microbiology. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b40703626afabb6843443b17fc4f9147
https://pubmed.ncbi.nlm.nih.gov/35114817
https://pubmed.ncbi.nlm.nih.gov/35114817