Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Chad Sanada"'
Autor:
Bianca C. T. Flores, Smriti Chawla, Ning Ma, Chad Sanada, Praveen Kumar Kujur, Rudy Yeung, Margot B. Bellon, Kyle Hukari, Brian Fowler, Mark Lynch, Ludmilla T. D. Chinen, Naveen Ramalingam, Debarka Sengupta, Stefanie S. Jeffrey
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-8 (2022)
A microfluidic system combines the capture, co-incubation, time-lapse imaging, and gene expression profiling of doublets to measure the distances between cells and associated transcriptional profiles due to cell–cell interactions.
Externí odkaz:
https://doaj.org/article/1332145f194e41f78d1b27d11c29bdd9
Autor:
Haibiao Gong, Xiaohui Wang, Benjamin Liu, Stephane Boutet, Ilona Holcomb, Gajalakshmi Dakshinamoorthy, Aik Ooi, Chad Sanada, Gang Sun, Ramesh Ramakrishnan
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract We have investigated the correlation between proteins and mRNAs in single cells employing an integrated workflow for dual-analyte co-detection. This is achieved by combining the oligo extension reaction (OER), which converts protein levels t
Externí odkaz:
https://doaj.org/article/d53b4a806b534842a54ad55e4e3c21e5
Autor:
Yi-Chien Lu, Chad Sanada, Juliana Xavier-Ferrucio, Lin Wang, Ping-Xia Zhang, H. Leighton Grimes, Meenakshi Venkatasubramanian, Kashish Chetal, Bruce Aronow, Nathan Salomonis, Diane S. Krause
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 2083-2093.e4 (2018)
Summary: Megakaryocytic-erythroid progenitors (MEPs) give rise to the cells that produce red blood cells and platelets. Although the mechanisms underlying megakaryocytic (MK) and erythroid (E) maturation have been described, those controlling their s
Externí odkaz:
https://doaj.org/article/bce482c85b4948edaf4518e6248cadfc
Autor:
Ludmilla Thomé Domingos Chinen, Kyle Hukari, Mark Lynch, Smriti Chawla, Debarka Sengupta, Chad Sanada, Naveen Ramalingam, Ning Ma, Bianca C. T. Flores, Praveen Kumar Kujur, Stefanie S. Jeffrey
Cell-cell communication and physical interactions play a vital role in cancer initiation, homeostasis, progression, and immune response. Here, we report a system that combines live capture of different cell types, co-incubation, time-lapse imaging, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a4a720d7972144ef08691aefe7fc3a
https://doi.org/10.1101/2021.11.13.468447
https://doi.org/10.1101/2021.11.13.468447
Autor:
Tyson R. Shepherd, Clint Davis, Charles D. Johnson, Stephen Tanner, Jocelyne Bruand, Thomas Hraha, Tian Tian, Steven Alvarez, Eric Abbate, Shea Lambert, Timothy M. Shaver, Bryan A Leland, Paul Hardenbol, Michael Graige, Stephen Federowicz, Mathew Barber, Scott Bolte, Christopher G. Abraham, Miles Gander, Simon Cawley, Gozde Gencer, J. Christian J. Ray, Andrew D. Garst, Richard Fox, Maciej Swat, Surbhi Jain, Matthew Estes, Kara Juneau, Craig A. Struble, Ken Wishart, Andrea L. Halweg-Edwards, Deanna M. Church, Francesca Pearson, Eileen Colie Spindler, Nandini Krishnamurthy, Chad Sanada, Joshua Shorenstein
Genome engineering methodologies are transforming biological research and discovery. Approaches based on CRISPR technology have been broadly adopted and there is growing interest in the generation of massively parallel edited cell libraries. Comparin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fe0e8bc1ff7b70e400f9a7f173cf58a
https://doi.org/10.1101/2021.09.23.458228
https://doi.org/10.1101/2021.09.23.458228
Autor:
Dominic Grün, Johannes W. Bagnoli, Catia Moutinho, Xian Adiconis, Atefeh Lafzi, Christoph Ziegenhain, Yasha Talaga, Kaori Tanaka, Ivo Gut, Adrián Álvarez-Varela, Cornelius Fischer, Tetsutaro Hayashi, Lucas E. Wange, Oliver Stegle, Joshua Z. Levin, Chad Sanada, Yohei Sasagawa, Stéphane C. Boutet, Sascha Sauer, Chris Brampton, Christian Conrad, Eduard Batlle, Kelly Kaihara, Davis J. McCarthy, Caroline Braeuning, Julia K. Lau, Itoshi Nikaido, Aik Ooi, Sagar, Holger Heyn, Swati Parekh, Aviv Regev, Marta Gut, Elisabetta Mereu, Wolfgang Enard, Timo Trefzer, Robert C. Jones, Lan T. Nguyen, Rickard Sandberg, Aleksandar Janjic
Publikováno v:
Nature Biotechnology
Nat Biotechnol
Nat Biotechnol
Single-cell RNA sequencing (scRNA-seq) is the leading technique for characterizing the transcriptomes of individual cells in a sample. The latest protocols are scalable to thousands of cells and are being used to compile cell atlases of tissues, orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc7654dc2cf52371306fb8076a810c1
Autor:
Kashish Chetal, Chad Sanada, Yi-Chien Lu, Lin Wang, Meenakshi Venkatasubramanian, Ping-Xia Zhang, H. Leighton Grimes, Diane S. Krause, Bruce J. Aronow, Nathan Salomonis, Juliana Xavier-Ferrucio
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 2083-2093.e4 (2018)
Cell reports
Cell reports
SUMMARY Megakaryocytic-erythroid progenitors (MEPs) give rise to the cells that produce red blood cells and platelets. Although the mechanisms underlying megakaryocytic (MK) and erythroid (E) maturation have been described, those controlling their sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5202bbc96463fa70df5860f13dafeb
http://www.sciencedirect.com/science/article/pii/S2211124718316887
http://www.sciencedirect.com/science/article/pii/S2211124718316887
Autor:
Aik Ooi, Chad Sanada
Publikováno v:
Methods in Molecular Biology ISBN: 9781493992393
Single-cell functional analysis provides a natural next step in the now widely adopted single-cell mRNA sequencing studies. Functional studies can be designed to study cellular context by using single-cell culture, perturbation, manipulation, or trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c73fd2cd19441b3b5e421a33ff490a5
https://doi.org/10.1007/978-1-4939-9240-9_12
https://doi.org/10.1007/978-1-4939-9240-9_12
Autor:
Steven Walker, Weihong Yin, Anthony Atala, Graça Almeida-Porada, Christopher D. Porada, Evan Colletti, Chad Sanada, Esmail D. Zanjani, Saloomeh Mokhtari, Colin E. Bishop, Paul J. Simmons, Zanetta S. Lamar
Publikováno v:
Leukemia
The presence, within the human bone marrow, of cells with both endothelial and hemogenic potential has been controversial. Herein, we identify, within the human fetal bone marrow, prior to establishment of hematopoiesis, a unique APLNR+, Stro-1+ cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b111fdd46dc67c196f10ea05ee0d8ae4
https://pubmed.ncbi.nlm.nih.gov/29891936
https://pubmed.ncbi.nlm.nih.gov/29891936
Autor:
Stéphane C. Boutet, Benjamin Liu, Ramesh Ramakrishnan, Chad Sanada, Haibiao Gong, Aik Ooi, Gang Sun, Ilona Holcomb, Xiaohui Wang, Gajalakshmi Dakshinamoorthy
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
We have investigated the correlation between proteins and mRNAs in single cells employing an integrated workflow for dual-analyte co-detection. This is achieved by combining the oligo extension reaction (OER), which converts protein levels to DNA lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f2756b367be7488d0d48ecf6b06858d
http://europepmc.org/articles/PMC5459813
http://europepmc.org/articles/PMC5459813