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pro vyhledávání: '"Chad S Vickers"'
Autor:
Larry Dick, Virendar K. Kaushik, Thomas F. Parsons, Peter J. Tummino, Susan L. Acton, Michael A. Patane, Kevin Godbout, Jin Tang, Elizabeth Baronas, Chad S Vickers, Frank Y. Hsieh, James M. Gavin, Paul Hales, Andrew J. Nichols
Publikováno v:
Journal of Biological Chemistry. 277:14838-14843
Human angiotensin-converting enzyme-related carboxypeptidase (ACE2) is a zinc metalloprotease whose closest homolog is angiotensin I-converting enzyme. To begin to elucidate the physiological role of ACE2, ACE2 was purified, and its catalytic activit
Autor:
Timothy D. Ocain, Alexandra E. Gould, Natalie A. Dales, James Brown, Emily F. Calderwood, James M. Gavin, Charles A. Minor, Bing Guan, Chad S Vickers, Virendar K. Kaushik, Paul Hales, Michael A. Patane, Peter J. Tummino, Michael Stewart
Publikováno v:
Journal of the American Chemical Society. 124:11852-11853
Angiotensin-converting enzyme-related carboxypeptidase (ACE2) is a recently identified zinc metalloprotease with carboxypeptidase activity that was identified using our genomics platform. We implemented a rational design approach to identify potent a