Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Chad R. Potts"'
Autor:
P. Brent Ferrell, Jean-Philippe Cartailler, Michael R. Savona, Ferrin C. Wheeler, Ashwini Yenamandra, Clinton Holt, Austin Brooks, Justin A. Cartailler, Pawan Bhat, Chad R. Potts, Tiffany Guess
Supplementary Figure from Distinct Patterns of Clonal Evolution Drive Myelodysplastic Syndrome Progression to Secondary Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0324fa3314e6a27e971270e3a78fb257
https://doi.org/10.1158/2643-3230.22545248.v1
https://doi.org/10.1158/2643-3230.22545248.v1
Autor:
P. Brent Ferrell, Jean-Philippe Cartailler, Michael R. Savona, Ferrin C. Wheeler, Ashwini Yenamandra, Clinton Holt, Austin Brooks, Justin A. Cartailler, Pawan Bhat, Chad R. Potts, Tiffany Guess
Supplementary Table from Distinct Patterns of Clonal Evolution Drive Myelodysplastic Syndrome Progression to Secondary Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0011a2d6559571b49b7b9edc2b9092ec
https://doi.org/10.1158/2643-3230.22545236.v1
https://doi.org/10.1158/2643-3230.22545236.v1
Autor:
P. Brent Ferrell, Jean-Philippe Cartailler, Michael R. Savona, Ferrin C. Wheeler, Ashwini Yenamandra, Clinton Holt, Austin Brooks, Justin A. Cartailler, Pawan Bhat, Chad R. Potts, Tiffany Guess
Clonal evolution in myelodysplastic syndrome (MDS) can result in clinical progression and secondary acute myeloid leukemia (sAML). To dissect changes in clonal architecture associated with this progression, we performed single-cell genotyping of pair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0ae6fc5152cecd48f345a61a4a8ed3
https://doi.org/10.1158/2643-3230.c.6550886
https://doi.org/10.1158/2643-3230.c.6550886
Autor:
J. Brett Heimlich, Pawan Bhat, Alyssa C. Parker, Matthew T. Jenkins, Caitlyn Vlasschaert, Jessica Ulloa, Chad R. Potts, Sydney Olson, Alexander J. Silver, Ayesha Ahmad, Brian Sharber, Donovan Brown, Ningning Hu, Peter van Galen, Michael R. Savona, Alexander G. Bick, P. Brent Ferrell
Clonal hematopoiesis (CH) is an age-associated phenomenon that increases risk for hematologic malignancy and cardiovascular disease. CH is thought to increase cardiovascular disease risk through inflammation in the peripheral blood1. Here, we profile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7333ae9154e8b7091944a3fe1d5abd56
https://doi.org/10.1101/2022.12.01.518580
https://doi.org/10.1101/2022.12.01.518580
Autor:
Pawan Bhat, J. Brett Heimlich, Alyssa Parker, Matthew T. Jenkins, Chad R. Potts, Jessica Ulloa, Alexander J. Silver, Donovan J. Brown, Peter Van Galen, Michael R. Savona, Alexander G. Bick, Brent Ferrell
Publikováno v:
Blood. 140:2891-2892
Autor:
Matthew T. Jenkins, Timothy J Scott, Lindsey N Guerin, Alana M Franceski, Yunli E Chu, Pawan Bhat, Chad R. Potts, Robert S. Welner, Emily Hodges, Brent Ferrell
Publikováno v:
Blood. 140:2883-2884
Autor:
Robert L. Bowman, Andrew Dunbar, Tanmay Mishra, Wenbin Xiao, Michael R. Waarts, Inés Fernández Maestre, Shira E. Eisman, Louise Cai, Sheng F. Cai, Pablo Sanchez Vela, Shoron Mowla, Anthony R. Martinez Benitez, Young Park, Isabelle S. Csete, Aishwarya Krishnan, Darren Lee, Nayla Boorady, Chad R. Potts, Matthew T. Jenkins, Martin P. Carroll, Sara E. Meyer, Linde A. Miles, P. Brent Ferrell, Jennifer J. Trowbridge, Ross L. Levine
SummaryCancer evolution is a multifaceted process involving the acquisition of somatic mutations and progressive epigenetic dysregulation of cellular fate. Both cell-intrinsic mechanisms and environmental interactions provide selective pressures capa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4913080bcc50fd4a9575f5edd3e21023
https://doi.org/10.1101/2022.05.18.492524
https://doi.org/10.1101/2022.05.18.492524
Autor:
Tiffany Guess, Chad R. Potts, Pawan Bhat, Justin A. Cartailler, Austin Brooks, Clinton Holt, Ashwini Yenamandra, Ferrin C. Wheeler, Michael R. Savona, Jean-Philippe Cartailler, P. Brent Ferrell
Publikováno v:
Blood Cancer Discov
Clonal evolution in myelodysplastic syndrome (MDS) can result in clinical progression and secondary acute myeloid leukemia (sAML). To dissect changes in clonal architecture associated with this progression, we performed single-cell genotyping of pair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301f4c456d8cda69ac4b5694c3fe86f9
https://europepmc.org/articles/PMC9610896/
https://europepmc.org/articles/PMC9610896/
Autor:
Shira E. Eisman, Tanmay Mishra, Robert L. Bowman, Jennifer J. Trowbridge, Paul Brent Ferrell, Ross L. Levine, Matthew T. Jenkins, Wenbin Xiao, Chad R. Potts, Michael R. Waarts, Inés Fernández-Maestre, Louise Cai, Isabelle S. Csete, Pablo Sanchez Vela, Linde A. Miles
Publikováno v:
Blood. 138:2220-2220
Genomic studies in acute myeloid leukemia (AML) have generated a near complete catalogue of genes mutated at varying frequencies both across patients and in individual leukemias. The high variability of mutation burden within a given leukemia is sugg
Autor:
Wendy Kimryn Rathmell, Matthew Z. Madden, Chad R. Potts, Benjamin J. Reisman, Paul Brent Ferrell, Zhuoyan Li, Jeffrey C. Rathmell, Bradley I. Reinfeld
Publikováno v:
Cancer Research. 80:1025-1025
Isocitrate dehydrogenase 1 or 2 (IDH1/2) mutations are recurrent in AML and introduce neomorphic function in this metabolic enzyme. The resulting accumulation of the oncometabolite R-2-hydroxyglutarate (2-HG) in leukemic cells leads to epigenetic cha