Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chad R. Clark"'
Autor:
Jian Zhong, Zhenqing Ye, Chad R. Clark, Samuel W. Lenz, Justin H. Nguyen, Huihuang Yan, Keith D. Robertson, Gianrico Farrugia, Zhiguo Zhang, Tamas Ordog, Jeong-Heon Lee
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract Background Epigenetic dysregulation is involved in the etiology and progression of various human diseases. Formalin-fixed paraffin-embedded (FFPE) samples represent the gold standard for archiving pathology samples, and thus FFPE samples are
Externí odkaz:
https://doaj.org/article/7044fd314269429e899c2c3944ee3a97
Autor:
Jian Zhong, Zhenqing Ye, Samuel W. Lenz, Chad R. Clark, Adil Bharucha, Gianrico Farrugia, Keith D. Robertson, Zhiguo Zhang, Tamas Ordog, Jeong-Heon Lee
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background Chromatin immunoprecipitation-sequencing (ChIP-seq) is a widely used epigenetic approach for investigating genome-wide protein-DNA interactions in cells and tissues. The approach has been relatively well established but several ke
Externí odkaz:
https://doaj.org/article/029d36e793094dfa8c6688c1c165354c
Autor:
Chad R. Clark, Zhenqing Ye, Jian Zhong, Huihuang Yan, Jeong Heon Lee, Keith D. Robertson, Justin H. Nguyen, Tamas Ordog, Zhiguo Zhang, Samuel W. Lenz, Gianrico Farrugia
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-11 (2019)
BMC Genomics
BMC Genomics
Background Epigenetic dysregulation is involved in the etiology and progression of various human diseases. Formalin-fixed paraffin-embedded (FFPE) samples represent the gold standard for archiving pathology samples, and thus FFPE samples are a major
Autor:
Eric V Marietta, Andres M Gomez, Carl Yeoman, Ashenafi Y Tilahun, Chad R Clark, David H Luckey, Joseph A Murray, Bryan A White, Yogish C Kudva, Govindarajan Rajagopalan
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78687 (2013)
Human and animal studies strongly suggest that dietary gluten could play a causal role in the etiopathogenesis of type 1 diabetes (T1D). However, the mechanisms have not been elucidated. Recent reports indicate that the intestinal microbiome has a ma
Externí odkaz:
https://doaj.org/article/e7614a3291b546dc8dd39befd8cb1725
Autor:
Samuel W. Lenz, Jian Zhong, Zhiguo Zhang, Jeong Heon Lee, Zhenqing Ye, Chad R. Clark, Keith D. Robertson, Gianrico Farrugia, Tamas Ordog, Adil E. Bharucha
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-10 (2017)
BMC Genomics
BMC Genomics
Background Chromatin immunoprecipitation-sequencing (ChIP-seq) is a widely used epigenetic approach for investigating genome-wide protein-DNA interactions in cells and tissues. The approach has been relatively well established but several key steps s
Autor:
Robin Patel, Suzannah M. Schmidt, Ashenafi Y. Tilahun, Melissa J. Karau, Chad R. Clark, Govindarajan Rajagopalan
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:5401-5405
Superantigens (SAg), the potent activators of the immune system, are important determinants of Staphylococcus aureus virulence and pathogenicity. Superior response to SAg in human leukocyte antigen (HLA)-DR3 transgenic mice rendered them more suscept
Autor:
Vaidehi R. Chowdhary, Joseph P. Grande, Chad R. Clark, Ashenafi Y. Tilahun, Govindarajan Rajagopalan
Publikováno v:
The Journal of Immunology. 189:2054-2062
Chronic nasal and skin colonization with superantigen (SAg)-producing Staphylococcus aureus is well documented in humans. Given that trans-mucosal and trans-cutaneous absorption of SAgs can occur, we determined whether chronic exposure to small amoun
Publikováno v:
Microbes and Infection. 14:528-536
Staphylococcal superantigens (SAg) are a family of potent exotoxins produced by Staphylococcus aureus. They play an important role in the pathogenesis of staphylococcal shock and pneumonia by causing a robust activation of the immune system and elici
Autor:
Huihuang Yan, Saurabh Baheti, John A. Smestad, Krutika S. Gaonkar, Michael L. Kendrick, Siva Arumugam Saravanaperumal, Molly Nelson Holte, Gianrico Farrugia, Yujiro Hayashi, Katie E. Miller, Fatimah J. Al Khazal, David R. Linden, Gabriella B. Gajdos, Zhifu Sun, Chad R. Clark, Sabriya A. Syed, Louis J. Maher, Jeong Heon Lee, Dieter Saur, Travis J. McKenzie, Todd A. Kellogg, Tamas Ordog
Publikováno v:
Gastroenterology. 152:S129-S130
Autor:
Carl J. Yeoman, David Luckey, Andres Gomez, Yogish C. Kudva, Bryan A. White, Chad R. Clark, Govindarajan Rajagopalan, Ashenafi Y. Tilahun, Joseph A. Murray, Eric V. Marietta
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 11, p e78687 (2013)
PLoS ONE, Vol 8, Iss 11, p e78687 (2013)
Human and animal studies strongly suggest that dietary gluten could play a causal role in the etiopathogenesis of type 1 diabetes (T1D). However, the mechanisms have not been elucidated. Recent reports indicate that the intestinal microbiome has a ma