Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Chad R, Borges"'
Autor:
Nilojan Jehanathan, Erandi P. Kapuruge, Stephen P. Rogers, Stacy Williams, Yunro Chung, Chad R. Borges
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 27, Iss , Pp 18-23 (2023)
Introduction: Oxidized LDL (oxLDL) is formed by the spontaneous reaction between aldehyde byproducts of lipid peroxidation and lysine residues of apolipoprotein B within LDL. Clinically, oxLDL is used as a marker of coronary artery disease and predic
Externí odkaz:
https://doaj.org/article/2a6c0c72fdab44c8a86d6d5062968759
Autor:
Jenifer Pendiuk Goncalves, Sierra A. Walker, Jesús S. Aguilar Díaz de león, Yubo Yang, Irina Davidovich, Sara Busatto, Jann Sarkaria, Yeshayahu Talmon, Chad R. Borges, Joy Wolfram
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8506 (2023)
Extracellular vesicles (EVs) play important roles in (patho)physiological processes by mediating cell communication. Although EVs contain glycans and glycosaminoglycans (GAGs), these biomolecules have been overlooked due to technical challenges in co
Externí odkaz:
https://doaj.org/article/c5ea95134109479f883f45aaa57ba5f6
Autor:
Sierra A. Walker, Jesús S. Aguilar Díaz De león, Sara Busatto, Gregory A. Wurtz, Abba C. Zubair, Chad R. Borges, Joy Wolfram
Publikováno v:
Cells, Vol 9, Iss 9, p 1946 (2020)
Blood plasma is a readily accessible source of extracellular vesicles (EVs), i.e., cell-secreted nanosized carriers that contain various biomolecules, including glycans. Previous studies have demonstrated that glycans play a major role in physiologic
Externí odkaz:
https://doaj.org/article/2874df470a634f7398c933fd1d005438
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201208 (2018)
Despite systemic therapy and cystectomy, bladder cancer is characterized by a high recurrence rate. Serum glycomics represents a promising source of prognostic markers for monitoring patients. Our approach, which we refer to as "glycan node analysis"
Externí odkaz:
https://doaj.org/article/5198a95d3d134034b0b1ebdcd4a1d44f
Autor:
Arpan Deb, William A Johnson, Alexander P Kline, Boston J Scott, Lydia R Meador, Dustin Srinivas, Jose M Martin-Garcia, Katerina Dörner, Chad R Borges, Rajeev Misra, Brenda G Hogue, Petra Fromme, Tsafrir S Mor
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172529 (2017)
Viral protein U (Vpu) is a type-III integral membrane protein encoded by Human Immunodeficiency Virus-1 (HIV- 1). It is expressed in infected host cells and plays several roles in viral progeny escape from infected cells, including down-regulation of
Externí odkaz:
https://doaj.org/article/b4bf8b971cc542fbb57eb2ed80c4af4c
Autor:
Erandi P. Kapuruge, Nilojan Jehanathan, Stephen P. Rogers, Stacy Williams, Yunro Chung, Chad R. Borges
Publikováno v:
Molecular & Cellular Proteomics. 21:100420
Biomolecular integrity can be compromised when blood plasma/serum (P/S) specimens are improperly handled. Compromised analytes can subsequently produce erroneous results-without any indication of having done so. We recently introduced an LC/MS-based
Autor:
Hussein N Yassine, Olgica Trenchevska, Huijuan He, Chad R Borges, Dobrin Nedelkov, Wendy Mack, Naoko Kono, Juraj Koska, Peter D Reaven, Randall W Nelson
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0115320 (2015)
Using mass spectrometric immunoassay, the abundance of SAA truncations relative to the native variants was examined in plasma of 91 participants with type 2 diabetes and chronic kidney disease and 69 participants without diabetes.The ratio of SAA 1.1
Externí odkaz:
https://doaj.org/article/d0938a116c82448d9396a5fa1e7ffe10
Autor:
Joshua W. Jeffs, Linda Pham, Christian S. Breburda, Stephanie M.F. Thibert, Zachary Wilson, Nilojan Jehanathan, Chad R. Borges, Shadi Ferdosi
Publikováno v:
Molecular & Cellular Proteomics : MCP
ΔS-Cys-Albumin, an endogenous marker of plasma and serum (P/S) exposure to thawed conditions (> −30 °C) based on the ex vivo S-cysteinylation (oxidizability) of albumin was developed. Average values in fresh P/S samples from a population of nonac
Autor:
Man Yang, Sierra A. Walker, Jesús S. Aguilar Díaz de león, Irina Davidovich, Kelly Broad, Yeshayahu Talmon, Chad R. Borges, Joy Wolfram
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 42:102515
Monocyte-induced endothelial cell inflammation is associated with multiple pathological conditions, and extracellular vesicles (EVs) are essential nanosized components of intercellular communication. EVs derived from endotoxin-stimulated monocytes we
Autor:
Paul E Oran, Olgica Trenchevska, Dobrin Nedelkov, Chad R Borges, Matthew R Schaab, Douglas S Rehder, Jason W Jarvis, Nisha D Sherma, Luhui Shen, Bryan Krastins, Dawn C Schwenke, Peter D Reaven, Randall W Nelson
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92801 (2014)
Insulin-like growth factor 1 (IGF1) is an important biomarker for the management of growth hormone disorders. Recently there has been rising interest in deploying mass spectrometric (MS) methods of detection for measuring IGF1. However, widespread cl
Externí odkaz:
https://doaj.org/article/bb85b97f782f4818917849d3347eec55