Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Chad M, Petit"'
Publikováno v:
Viruses, Vol 15, Iss 10, p 2063 (2023)
The Influenza A virus is a continuous threat to public health that causes yearly epidemics with the ever-present threat of the virus becoming the next pandemic. Due to increasing levels of resistance, several of our previously used antivirals have be
Externí odkaz:
https://doaj.org/article/8df904fcec104916bf1636350744aba9
Autor:
Norberto Gonzalez-Juarbe, Ashleigh N. Riegler, Alexander S. Jureka, Ryan P. Gilley, Jeffrey D. Brand, John E. Trombley, Ninecia R. Scott, Maryann P. Platt, Peter H. Dube, Chad M. Petit, Kevin S. Harrod, Carlos J. Orihuela
Publikováno v:
Cell Reports, Vol 32, Iss 8, Pp 108062- (2020)
Summary: Pneumonias caused by influenza A virus (IAV) co- and secondary bacterial infections are characterized by their severity and high mortality rate. Previously, we have shown that bacterial pore-forming toxin (PFT)-mediated necroptosis is a key
Externí odkaz:
https://doaj.org/article/b804d5f73aa147ecb872b34cc558199e
Autor:
Chad M. Petit, Andrew M. Clarke, David A. Schneider, Yvonne J. K. Edwards, Abigail K. Huffines
Publikováno v:
Genes; Volume 12; Issue 12; Pages: 1939
Genes, Vol 12, Iss 1939, p 1939 (2021)
Genes
Genes, Vol 12, Iss 1939, p 1939 (2021)
Genes
Saccharomyces cerevisiae has approximately 200 copies of the 35S rDNA gene, arranged tandemly on chromosome XII. This gene is transcribed by RNA polymerase I (Pol I) and the 35S rRNA transcript is processed to produce three of the four rRNAs required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827e818c15b2900f6b95d433f3244358
Autor:
Hayden T, Pacl, Jennifer L, Tipper, Ritesh R, Sevalkar, Andrew, Crouse, Camerron, Crowder, Shama, Ahmad, Aftab, Ahmad, Gillian D, Holder, Charles J, Kuhlman, Krishna C, Chinta, Sajid, Nadeem, Todd J, Green, Chad M, Petit, Adrie J C, Steyn, Matthew, Might, Kevin S, Harrod
Publikováno v:
bioRxiv
SummaryThe recent emergence of a novel coronavirus, SARS-CoV-2, has led to the global pandemic of the severe disease COVID-19 in humans. While efforts to quickly identify effective antiviral therapies have focused largely on repurposing existing drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29694efb999bf0d12d02febad87da12f
https://pubmed.ncbi.nlm.nih.gov/34282419
https://pubmed.ncbi.nlm.nih.gov/34282419
Autor:
Chad M. Petit, Terje Dokland, Shihong Qiu, Joseph R. Gould, Tomoaki Ogino, Todd Green, Qiao Shang
Publikováno v:
J Virol
Vesicular stomatitis virus (VSV) is a member of the order Mononegavirales, which consists of viruses with genomes of nonsegmented negative-sense (NNS) RNA. Many insights into the molecular biology of NNS viruses were first made in VSV, which is often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d9c61fe758ae86397e4b9c2d4bd254
https://doi.org/10.1128/jvi.02180-20
https://doi.org/10.1128/jvi.02180-20
Publikováno v:
Journal of Virology
bioRxiv
article-version (status) pre
article-version (number) 1
bioRxiv
article-version (status) pre
article-version (number) 1
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the COVID-19 pandemic. One protein known to play a critical role in the coronavirus life cycle is nonstructural protein 1 (nsp1).
The periodic emergence of no
The periodic emergence of no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8d06803ca76ac05df5475f8fe33ecc
Autor:
Chad M. Petit, Todd Green, Tomoaki Ogino, Joseph R. Gould, Peter E. Prevelige, Shihong Qiu, Qiao Shang
Publikováno v:
J Virol
Vesicular stomatitis virus (VSV) is an archetypical member of Mononegavirales, viruses with a genome of negative-sense single-stranded RNA (−ssRNA). Like other viruses of this order, VSV encodes a unique polymerase, a complex of viral L (large, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5613fa8833a7cd863892c20751ce2729
https://doi.org/10.1128/jvi.01729-19
https://doi.org/10.1128/jvi.01729-19
Autor:
Alexander S. Jureka, Peter H. Dube, Ryan P. Gilley, Norberto Gonzalez-Juarbe, Ninecia R. Scott, Jeffrey D. Brand, Chad M. Petit, Kevin S. Harrod, Ashleigh N. Riegler, John E. Trombley, Carlos J. Orihuela
RationalePneumonia caused by Influenza A virus (IAV) co- and secondary bacterial infections are characterized by their severity. Previously we have shown that pore-forming toxin (PFT)-mediated necroptosis is a key driver of acute lung injury during b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635f214de8d633b00d4f71705ae6f9c5
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33252 (2012)
It is well known that enzyme flexibility is critical for function. This is due to the observation that the rates of intramolecular enzyme motions are often matched to the rates of intermolecular events such as substrate binding and product release. B
Externí odkaz:
https://doaj.org/article/ca0cc0d6c6574d1c914286564917b203
Publikováno v:
Journal of the American Chemical Society. 139:3599-3602
Allostery enables tight regulation of protein function in the cellular environment. Although existing models of allostery are firmly rooted in the current structure-function paradigm, the mechanistic basis for allostery in the absence of structural c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515058d734a0471c441240657a7fe858
https://doi.org/10.1021/jacs.6b12058
https://doi.org/10.1021/jacs.6b12058