Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Chad Lerner"'
Autor:
Alessandro Bitto, Chad Lerner, Claudio Torres, Michaela Roell, Marco Malaguti, Viviana Perez, Antonello Lorenzini, Silvana Hrelia, Yuji Ikeno, Michelle Elizabeth Matzko, Roger McCarter, Christian Sell
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12592 (2010)
A reduction in IGF-I signaling has been found to increase lifespan in multiple organisms despite the fact that IGF-I is a trophic factor for many cell types and has been found to have protective effects against multiple forms of damage in acute setti
Externí odkaz:
https://doaj.org/article/e420605603604e01bfb99bab7f48bf22
Autor:
Jodi Nunnari, Chad Lerner, Shona A. Mookerjee, Eddy Gibbs, Katherine Labbé, Maxence Le Vasseur
Publikováno v:
The Journal of cell biology. 220(11)
Mitochondrial function is integrated with cellular status through the regulation of opposing mitochondrial fusion and division events. Here we uncover a link between mitochondrial dynamics and lipid metabolism by examining the cellular role of mitoch
Autor:
Chad Lerner, Diem T. Le, Justin Ton, Akos A. Gerencser, Shona A. Mookerjee, Maurice L Brady, Jordon N. Mar, Maggie C. Louie
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology, Vol 10 (2020)
Cancer growth is predicted to require substantial rates of substrate catabolism and ATP turnover to drive unrestricted biosynthesis and cell growth. While substrate limitation can dramatically alter cell behavior, the effects of substrate limitation
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1859:e65
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1859:e65
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1170
All living organisms are subject to progressive loss of function and damage to their tissues, a process known as aging. At the cellular level, the accumulation of damage to DNA, proteins, and organelles induces cellular senescence, a stress-response