Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Chad K. Park"'
Autor:
Amber D. Rolland, Chad K. Park, Jun Wang, Nancy C. Horton, Julia Alma Townsend, Michael T. Marty, Henry M. Sanders, James S. Prell
Publikováno v:
Anal Chem
Viroporins are small viral ion channels that play important roles in the viral infection cycle and are proven antiviral drug targets. Matrix protein 2 from influenza A (AM2) is the best characterized viroporin, and the current paradigm is that AM2 fo
Autor:
Chad K. Park, Nancy Horton
Publikováno v:
The FASEB Journal. 36
Autor:
Huaying Zhao, Rodolfo Ghirlando, Carlos Alfonso, Fumio Arisaka, Ilan Attali, David L Bain, Marina M Bakhtina, Donald F Becker, Gregory J Bedwell, Ahmet Bekdemir, Tabot M D Besong, Catherine Birck, Chad A Brautigam, William Brennerman, Olwyn Byron, Agnieszka Bzowska, Jonathan B Chaires, Catherine T Chaton, Helmut Cölfen, Keith D Connaghan, Kimberly A Crowley, Ute Curth, Tina Daviter, William L Dean, Ana I Díez, Christine Ebel, Debra M Eckert, Leslie E Eisele, Edward Eisenstein, Patrick England, Carlos Escalante, Jeffrey A Fagan, Robert Fairman, Ron M Finn, Wolfgang Fischle, José García de la Torre, Jayesh Gor, Henning Gustafsson, Damien Hall, Stephen E Harding, José G Hernández Cifre, Andrew B Herr, Elizabeth E Howell, Richard S Isaac, Shu-Chuan Jao, Davis Jose, Soon-Jong Kim, Bashkim Kokona, Jack A Kornblatt, Dalibor Kosek, Elena Krayukhina, Daniel Krzizike, Eric A Kusznir, Hyewon Kwon, Adam Larson, Thomas M Laue, Aline Le Roy, Andrew P Leech, Hauke Lilie, Karolin Luger, Juan R Luque-Ortega, Jia Ma, Carrie A May, Ernest L Maynard, Anna Modrak-Wojcik, Yee-Foong Mok, Norbert Mücke, Luitgard Nagel-Steger, Geeta J Narlikar, Masanori Noda, Amanda Nourse, Tomas Obsil, Chad K Park, Jin-Ku Park, Peter D Pawelek, Erby E Perdue, Stephen J Perkins, Matthew A Perugini, Craig L Peterson, Martin G Peverelli, Grzegorz Piszczek, Gali Prag, Peter E Prevelige, Bertrand D E Raynal, Lenka Rezabkova, Klaus Richter, Alison E Ringel, Rose Rosenberg, Arthur J Rowe, Arne C Rufer, David J Scott, Javier G Seravalli, Alexandra S Solovyova, Renjie Song, David Staunton, Caitlin Stoddard, Katherine Stott, Holger M Strauss, Werner W Streicher, John P Sumida, Sarah G Swygert, Roman H Szczepanowski, Ingrid Tessmer, Ronald T Toth, Ashutosh Tripathy, Susumu Uchiyama, Stephan F W Uebel, Satoru Unzai, Anna Vitlin Gruber, Peter H von Hippel, Christine Wandrey, Szu-Huan Wang, Steven E Weitzel, Beata Wielgus-Kutrowska, Cynthia Wolberger, Martin Wolff, Edward Wright, Yu-Sung Wu, Jacinta M Wubben, Peter Schuck
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126420 (2015)
Analytical ultracentrifugation (AUC) is a first principles based method to determine absolute sedimentation coefficients and buoyant molar masses of macromolecules and their complexes, reporting on their size and shape in free solution. The purpose o
Externí odkaz:
https://doaj.org/article/3bd91e8f42734f39965350067490e003
Autor:
Santosh Shah, Jonathan Sanchez, Andrew Stewart, Michael M Piperakis, Richard Cosstick, Claire Nichols, Chad K Park, Xin Ma, Vicki Wysocki, Jurate Bitinaite, Nancy C Horton
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124783 (2015)
SgrAI is a type II restriction endonuclease with an unusual mechanism of activation involving run-on oligomerization. The run-on oligomer is formed from complexes of SgrAI bound to DNA containing its 8 bp primary recognition sequence (uncleaved or cl
Externí odkaz:
https://doaj.org/article/8bc2b7b050ce4b50b34a28f260e16021
Autor:
Chad K. Park, Jonathan L. Sanchez, Christian Hernandez, Claudia Barahona, L. Emilia Basantes, Juan A. Sanchez, Nancy C. Horton
Publikováno v:
Journal of Biological Chemistry. 293:14585-14598
Filament or run-on oligomer formation by metabolic enzymes is now recognized as a widespread phenomenon having potentially unique enzyme regulatory properties and biological roles, and its dysfunction is implicated in human diseases such as cancer, d
Autor:
Chad K Park, Hemant K Joshi, Alka Agrawal, M Imran Ghare, Elizabeth J Little, Pete W Dunten, Jurate Bitinaite, Nancy C Horton
Publikováno v:
PLoS Biology, Vol 8, Iss 12, p e1000554 (2010)
SgrAI is a type IIF restriction endonuclease that cuts an unusually long recognition sequence and exhibits allosteric self-modulation of cleavage activity and sequence specificity. Previous studies have shown that DNA bound dimers of SgrAI oligomeriz
Externí odkaz:
https://doaj.org/article/fc8be480579840c180cff46a54d26e20
Autor:
Chad K. Park, Nancy C. Horton
Publikováno v:
Nature Reviews Molecular Cell Biology
Enzyme filaments are defined as reversible, functional, linear self-assemblies of a single type of enzyme. Filamentation has recently emerged as a new mode of enzymatic regulation. In this Comment, we briefly introduce the diversity and functional co
Autor:
Chad K. Park, Nancy C. Horton
Publikováno v:
Biophysical Reviews
Filament formation by non-cytoskeletal enzymes has been known for decades, yet only relatively recently has its wide-spread role in enzyme regulation and biology come to be appreciated. This comprehensive review summarizes what is known for each enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc9b1048d70ecf0aaea1fa5e16ee4a2
http://arxiv.org/abs/1909.13141
http://arxiv.org/abs/1909.13141
Publikováno v:
Journal of molecular recognition : JMRREFERENCES. 32(11)
It is well known the dimerization state of receptor tyrosine kinases (RTKs), in conjunction with binding partners such as the growth factor receptor bound protein 7 (Grb7) protein, plays an important role in cell signaling regulation. Previously, we
Autor:
Chad K. Park
Publikováno v:
The FASEB Journal. 33