Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Chad E. Grueter"'
Autor:
George R. Marcotte, Matthew J. Miller, Hawley E. Kunz, Zachary C. Ryan, Matthew D. Strub, Patrick M. Vanderboom, Carrie J. Heppelmann, Sarah Chau, Zachary D. Von Ruff, Sean P. Kilroe, Andrew T. McKeen, Jason M. Dierdorff, Jennifer I. Stern, Karl A. Nath, Chad E. Grueter, Vitor A. Lira, Andrew R. Judge, Blake B. Rasmussen, K. Sreekumaran Nair, Ian R. Lanza, Scott M. Ebert, Christopher M. Adams
Publikováno v:
JCI Insight, Vol 8, Iss 22 (2023)
Aging and many illnesses and injuries impair skeletal muscle mass and function, but the molecular mechanisms are not well understood. To better understand the mechanisms, we generated and studied transgenic mice with skeletal muscle–specific expres
Externí odkaz:
https://doaj.org/article/af1307b64c1b4419953e38f85ed47944
Autor:
Evangeline L. Scheibe, Chad E. Grueter
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/b6311ed170e44b039293887399b07ed1
Autor:
Jessica M. Ponce, Grace Coen, Kathryn M. Spitler, Nikola Dragisic, Ines Martins, Antentor Hinton, Margaret Mungai, Satya Murthy Tadinada, Hao Zhang, Gavin Y. Oudit, Long‐Sheng Song, Na Li, Peter Sicinski, Stefan Strack, E. Dale Abel, Colleen Mitchell, Duane D. Hall, Chad E. Grueter
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 7 (2020)
Background Nuclear‐to‐mitochondrial communication regulating gene expression and mitochondrial function is a critical process following cardiac ischemic injury. In this study, we determined that cyclin C, a component of the Mediator complex, regu
Externí odkaz:
https://doaj.org/article/25e15a470a0d4ce8a662239933b791ad
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 6 (2016)
Externí odkaz:
https://doaj.org/article/f71ec23774714ae8b82bb8ec96ffacc0
Autor:
Jinxi Wang, Qian Shi, Yihui Wang, Logan W. Dawson, Grace Ciampa, Weiyang Zhao, Guangqin Zhang, Biyi Chen, Robert M. Weiss, Chad E. Grueter, Duane D. Hall, Long-Sheng Song
Publikováno v:
Circulation research. 130(9)
Background: Transcriptional remodeling is known to contribute to heart failure (HF). Targeting stress-dependent gene expression mechanisms may represent a clinically relevant gene therapy option. We recently uncovered a salutary mechanism in the hear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f1cb6c2e6cbdf0b2d8de4dbb0d720a
https://pubmed.ncbi.nlm.nih.gov/35482830
https://pubmed.ncbi.nlm.nih.gov/35482830
Autor:
Bart Vanhaesebroeck, Abul K. Azad, Xueyi Chen, Pavel Zhabyeyev, Zamaneh Kassiri, Allan G. Murray, Chad E. Grueter, Gavin Y. Oudit
Publikováno v:
Journal of Molecular and Cellular Cardiology. 157:17-30
Background PI3Kα (Phosphoinositide 3-kinase α) regulates multiple downstream signaling pathways controlling cell survival, growth, and proliferation and is an attractive therapeutic target in cancer and obesity. The clinically-approved PI3Kα inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47e09c8ef54f41dee1619643cf1a17b
https://doi.org/10.1016/j.yjmcc.2021.04.004
https://doi.org/10.1016/j.yjmcc.2021.04.004
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a60b5f998ec865ca6f067e9548f6f43
https://doi.org/10.1096/fasebj.2022.36.s1.r2395
https://doi.org/10.1096/fasebj.2022.36.s1.r2395
Autor:
Alexis M. Oppman, Richard N. Gardner, Ines Martins, Rachel A. Minerath, Duane D. Hall, Chad E. Grueter
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::771d92eea8e5c2d5c2d7e3adadf2462f
https://doi.org/10.1096/fasebj.2022.36.s1.r3466
https://doi.org/10.1096/fasebj.2022.36.s1.r3466
Autor:
Matthew P. Harris, Quan J. Zhang, Cole T. Cochran, Jessica Ponce, Sean Alexander, Ana Kronemberger, Jordan D. Fuqua, Yuan Zhang, Ranan Fattal, Tyler Harper, Matthew L. Murry, Chad E. Grueter, E. Dale Abel, Vitor A. Lira
Impairments in macroautophagy/autophagy, which degrades dysfunctional organelles as well as long-lived and aggregate proteins, are associated with several cardiomyopathies; however, the regulation of cardiac autophagy remains insufficiently understoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cb7b7b8865b82c2de78fae87631a13
Publikováno v:
Journal of Molecular and Cellular Cardiology. 129:27-38
Thyroid hormone (TH) is a key regulator of transcriptional homeostasis in the heart. While hypothyroidism is known to result in adverse cardiac effects, the molecular mechanisms that modulate TH signaling are not completely understood. Mediator is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd54f3310482bd6c82f2e55577168ad
https://doi.org/10.1016/j.yjmcc.2019.01.007
https://doi.org/10.1016/j.yjmcc.2019.01.007