Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Chad Cummings"'
Autor:
Chad Cummings, Amber Lucas, Jonathan S. Minden, Bibifatima Kaupbayeva, Alan J. Russell, Hironobu Murata
Publikováno v:
ACS Applied Polymer Materials. 1:2897-2906
After labeling of proteins with chemical tags, the unconjugated tag that remains in solution must be removed to prevent interference with downstream workflows. Currently, unconjugated tags are remo...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15056fea989ab83dfe23b1bb1ba3ae73
https://doi.org/10.1021/acsapm.9b00611
https://doi.org/10.1021/acsapm.9b00611
Autor:
Rebecca L. Ball, Hironobu Murata, Alan J. Russell, Kathryn A. Whitehead, Katherine C. Fein, Chad Cummings
Publikováno v:
Journal of Controlled Release. 255:270-278
Despite its patient-friendliness, the oral route is not yet a viable strategy for the delivery of biomacromolecular therapeutics. This is, in part, due to the large size of proteins, which greatly limits their absorption across the intestinal epithel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16362b2c13710550e6922bbdc04e3c9
https://doi.org/10.1016/j.jconrel.2017.04.035
https://doi.org/10.1016/j.jconrel.2017.04.035
Publikováno v:
ACS Macro Letters. 5:493-497
While most effective in aqueous environments, enzymes are also able to catalyze reactions in essentially anhydrous organic media. Enzyme activity in organic solvents is limited as a result of inefficient substrate binding, lack of solubility, and ina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9768a0fcea7c19b96f961eef6296ccb0
https://doi.org/10.1021/acsmacrolett.6b00137
https://doi.org/10.1021/acsmacrolett.6b00137
Autor:
Chad Cummings, Allie C. Obermeyer
Publikováno v:
Biochemistry. 57(3)
Membraneless organelles, like membrane-bound organelles, are essential to cell homeostasis and provide discrete cellular subcompartments. Unlike classical organelles, membraneless organelles possess no physical barrier but rather arise by phase separ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8398a10f7df3d0aa90491f615ea09f84
https://pubmed.ncbi.nlm.nih.gov/29210575
https://pubmed.ncbi.nlm.nih.gov/29210575
Autor:
Sheiliza, Carmali, Hironobu, Murata, Chad, Cummings, Krzysztof, Matyjaszewski, Alan J, Russell
Publikováno v:
Methods in enzymology. 590
Atom transfer radical polymerization (ATRP) from the surface of a protein can generate remarkably dense polymer shells that serve as armor and rationally tune protein function. Using straightforward chemistry, it is possible to covalently couple or d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::467a531f1a1da383d5186e73a45f3b4a
https://pubmed.ncbi.nlm.nih.gov/28411645
https://pubmed.ncbi.nlm.nih.gov/28411645
Autor:
Chad Cummings, Stefanie L. Baker, Alan Campbell, Sheiliza Carmali, Hironobu Murata, Alan J. Russell
Publikováno v:
Biomacromolecules. 18(2)
The reduced immunogenicity and increased stability of protein-polymer conjugates has made their use in therapeutic applications particularly attractive. However, the physicochemical interactions between polymer and protein, as well as the effect of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4e2c2e43159360b8bdfe8b94b44b10
https://pubmed.ncbi.nlm.nih.gov/28081602
https://pubmed.ncbi.nlm.nih.gov/28081602
Atom transfer radical polymerization (ATRP) from the surface of a protein can generate remarkably dense polymer shells that serve as armor and rationally tune protein function. Using straightforward chemistry, it is possible to covalently couple or d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f90879265586263a7f6dccb6b5a777ee
https://doi.org/10.1016/bs.mie.2016.12.005
https://doi.org/10.1016/bs.mie.2016.12.005
Publikováno v:
Biomaterials. 34:7437-7443
Polymer-based protein engineering (PBPE) offers an attractive method to predictably modify and enhance enzyme structure and function. Using polymers that respond to stimuli such as temperature and pH, enzyme activity and stability can be predictably
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547b853cb515f91e9dc4816b3f4da0a9
https://doi.org/10.1016/j.biomaterials.2013.06.027
https://doi.org/10.1016/j.biomaterials.2013.06.027
Publikováno v:
Biomacromolecules. 14:1919-1926
The attachment of inert polymers, such as polyethylene glycol, to proteins has driven the emergence of a multibillion dollar biotechnology industry. In all cases, proteins have been stabilized or altered by covalently coupling the pre-existing polyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478e9ae191e223ba2b333e75ae9c7a46
https://doi.org/10.1021/bm4002816
https://doi.org/10.1021/bm4002816
Autor:
David M. Engle, Samuel D. Fuhlendorf, Christopher M. O’Meilia, John R. Weir, D. Chad Cummings
Publikováno v:
Agriculture, Ecosystems & Environment. 132:1-6
Herbicides have been applied extensively on rangelands to reduce forbs that were considered undesirable, which has been assumed to lead to an increase in grass production and ultimately to an improvement in livestock performance. While scores of rese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::881b9b886b30c9cd9559e7d1bdd0fe16
https://doi.org/10.1016/j.agee.2009.02.015
https://doi.org/10.1016/j.agee.2009.02.015