Behavioral and electrophysiological characterization of Dyt1 heterozygous knockout mice.

Autor: Fumiaki Yokoi, Huan-Xin Chen, Mai Tu Dang, Chad C Cheetham, Susan L Campbell, Steven N Roper, J David Sweatt, Yuqing Li

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0120916 (2015)

DYT1 dystonia is an inherited movement disorder caused by mutations in DYT1 (TOR1A), which codes for torsinA. Most of the patients have a trinucleotide deletion (ΔGAG) corresponding to a glutamic acid in the C-terminal region (torsinA(ΔE)). Dyt1 Δ

Externí odkaz: https://doaj.org/article/f358a7afcaec458fbca1b68aab27d38b

Enhanced hippocampal long-term potentiation and fear memory in Btbd9 mutant mice.

Autor: Mark P DeAndrade, Li Zhang, Atbin Doroodchi, Fumiaki Yokoi, Chad C Cheetham, Huan-Xin Chen, Steven N Roper, J David Sweatt, Yuqing Li

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e35518 (2012)

Polymorphisms in BTBD9 have recently been associated with higher risk of restless legs syndrome (RLS), a neurological disorder characterized by uncomfortable sensations in the legs at rest that are relieved by movement. The BTBD9 protein contains a B

Externí odkaz: https://doaj.org/article/38820f198fbe4df78498e134850cb750

An anticholinergic reverses motor control and corticostriatal LTD deficits in Dyt1 ΔGAG knock-in mice

Autor: David M. Lovinger, Mai T. Dang, Viet Vo, Jun Lu, Chad C. Cheetham, Yuqing Li, Fumiaki Yokoi

Publikováno v: Behavioural Brain Research. 226:465-472

DYT1 early-onset generalized torsion dystonia is an inherited movement disorder associated with mutations in DYT1 that codes for torsinA protein. The most common mutation seen in this gene is a trinucleotide deletion of GAG. We previously reported a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52866ee0f6c93014f73cca9e42a231c4
https://doi.org/10.1016/j.bbr.2011.10.002

Permanently compromised NADPH-diaphorase activity within the osmotically activated supraoptic nucleus after in utero but not adult exposure to Aroclor 1254.

Autor: Coburn CG; Environmental Toxicology Graduate Program, University of California, Riverside 92521, USA., Watson-Siriboe A; Department of Cell Biology and Neuroscience, University of California, Riverside 92521, USA., Hou B; Department of Cell Biology and Neuroscience, University of California, Riverside 92521, USA., Cheetham C; Department of Cell Biology and Neuroscience, University of California, Riverside 92521, USA., Gillard ER; Department of Cell Biology and Neuroscience, University of California, Riverside 92521, USA., Lin L; Department of Cell Biology and Neuroscience, University of California, Riverside 92521, USA., León-Olea M; Departamento de Neuromorfologia, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría 'Ramón de la Fuente Muñiz', Ave. México-Xochimilco 101, Col. San Lorenzo Huipulco, C.P. 14370 México, D.F., Mexico., Sánchez-Islas E; Departamento de Neuromorfologia, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría 'Ramón de la Fuente Muñiz', Ave. México-Xochimilco 101, Col. San Lorenzo Huipulco, C.P. 14370 México, D.F., Mexico., Mucio-Ramírez S; Departamento de Neuromorfologia, Dirección de Investigaciones en Neurociencias, Instituto Nacional de Psiquiatría 'Ramón de la Fuente Muñiz', Ave. México-Xochimilco 101, Col. San Lorenzo Huipulco, C.P. 14370 México, D.F., Mexico., Currás-Collazo MC; Environmental Toxicology Graduate Program, University of California, Riverside 92521, USA; Department of Cell Biology and Neuroscience, University of California, Riverside 92521, USA. Electronic address: mcur@ucr.edu.

Publikováno v: Neurotoxicology [Neurotoxicology] 2015 Mar; Vol. 47, pp. 37-46. Date of Electronic Publication: 2015 Jan 05.