Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Chad Bousman"'
Autor:
Sibel Saya, Patty Chondros, Anastasia Abela, Cathrine Mihalopolous, Mary Lou Chatterton, Jane Gunn, Timothy F. Chen, Thomas M. Polasek, Elise Dettmann, Rachel Brooks, Michelle King, Luke Spencer, Pavithran Alphonse, Shakira Milton, Georgia Ramsay, Zoe Siviour, Jamie Liew, Philip Ly, Matthew Thoenig, Raushaan Seychell, Floriana La Rocca, Luke B. Hesson, Nydia Mejias, Terri Sivertsen, Melanie Anne Galea, Chad Bousman, Jon Emery
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Background The evidence for the clinical utility of pharmacogenomic (PGx) testing is growing, and guidelines exist for the use of PGx testing to inform prescribing of 13 antidepressants. Although previous randomised controlled trials of PGx
Externí odkaz:
https://doaj.org/article/55d8406932cd4f07b01ea962249ddd20
Autor:
Sam Mostafa, Thomas M. Polasek, Chad Bousman, Amin Rostami‐Hodjegan, Leslie J. Sheffield, Ian Everall, Christos Pantelis, Carl M. J. Kirkpatrick
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 2, Pp 168-179 (2023)
Abstract Studies that focus on individual covariates, while ignoring their interactions, may not be adequate for model‐informed precision dosing (MIPD) in any given patient. Genetic variations that influence protein synthesis should be studied in c
Externí odkaz:
https://doaj.org/article/730d77bd6c7e4a90974bd9c7af6e6367
Autor:
Thomas P. Nguyen, Lachlan Cribb, Chee H. Ng, Gerard J. Byrne, David Castle, Vlasios Brakoulias, Scott Blair-West, Georgina Oliver, Carolyn Ee, Olivia M. Dean, David A. Camfield, Chad Bousman, Nathan Dowling, Rajshri Roy, Michael Berk, Jerome Sarris
Publikováno v:
BJPsych Open, Vol 7 (2021)
Background Many mental disorders, including depression, bipolar disorder and schizophrenia, are associated with poor dietary quality and nutrient intake. There is, however, a deficit of research looking at the relationship between obsessive–compuls
Externí odkaz:
https://doaj.org/article/b234386b90974532ae61195de5a5159b
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Schizophrenia is a psychiatric disorder with a worldwide prevalence of ∼1%. The high heritability and reduced fertility among schizophrenia patients have raised an evolutionary paradox: why has negative selection not eliminated schizophrenia associ
Externí odkaz:
https://doaj.org/article/da5568cf3bbb4fb492253276deb91fd8
Autor:
Md Shaki Mostaid, Ting Ting Lee, Gursharan Chana, Suresh Sundram, Cynthia Shannon Weickert, Christos Pantelis, Ian Everall, Chad Bousman
Publikováno v:
Frontiers in Psychiatry, Vol 8 (2017)
Investigation of peripheral gene expression patterns of transcripts within the NRG–ErbB signaling pathway, other than neuregulin-1 (NRG1), among patients with schizophrenia and more specifically treatment-resistant schizophrenia (TRS) is limited. T
Externí odkaz:
https://doaj.org/article/b23f47317ad848f1a0cca3013d2fe7cd
Autor:
Sam Mostafa, Thomas M. Polasek, Chad Bousman, Amin Rostami‐Hodjegan, Leslie J. Sheffield, Ian Everall, Christos Pantelis, Carl M. J. Kirkpatrick
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 12:168-179
Studies that focus on individual covariates, while ignoring their interactions, may not be adequate for model-informed precision dosing (MIPD) in any given patient. Genetic variations that influence protein synthesis should be studied in conjunction
Autor:
Amit Lotan, Sandra Luza, Carlos M. Opazo, Scott Ayton, Darius J. R. Lane, Serafino Mancuso, Avril Pereira, Suresh Sundram, Cynthia Shannon Weickert, Chad Bousman, Christos Pantelis, Ian P. Everall, Ashley I. Bush
Publikováno v:
Molecular Psychiatry.
Despite loss of grey matter volume and emergence of distinct cognitive deficits in young adults diagnosed with schizophrenia, current treatments for schizophrenia do not target disruptions in late maturational reshaping of the prefrontal cortex. Iron
Autor:
Dhamidhu Eratne, Shorena Janelidze, Charles B Malpas, Samantha Loi, Mark Walterfang, Antonia Merritt, Ibrahima Diouf, Kaj Blennow, Henrik Zetterberg, Brandon Cilia, Cassandra Wannan, Chad Bousman, Ian Everall, Andrew Zalesky, Mahesh Jayaram, Naveen Thomas, Samuel F Berkovic, Oskar Hansson, Dennis Velakoulis, Christos Pantelis, Alexander Santillo, Qiao-Xin Li, Christiane Stehmann, Claire Cadwallader, Christopher Fowler, Parsa Ravanfar, Sarah Farrand, Michael Keem, Matthew Kang, Rosie Watson, Nawaf Yassi, Cath Kaylor-Hughes, Richard Kanaan, Piero Perucca, Lucy Vivash, Rashida Ali, Terence J. O’Brien, Colin L Masters, Steven Collins, Wendy Kelso, Andrew Evans, Anna King, Patrick Kwan, Jane Gunn, Ilias Goranitis, Tianxin Pan, Courtney Lewis, Tomas Kalincik
Publikováno v:
Australian & New Zealand Journal of Psychiatry. 56:1295-1305
Objective: Schizophrenia, a complex psychiatric disorder, is often associated with cognitive, neurological and neuroimaging abnormalities. The processes underlying these abnormalities, and whether a subset of people with schizophrenia have a neuropro
Autor:
Chad Bousman, Meagan Hayashi
Publikováno v:
Pharmacy; Volume 10; Issue 6; Pages: 139
Background: Despite evidence of clinical utility and the availability of prescription guidelines, pharmacogenomics (PGx) is not broadly used in institutional settings in Canada. To inform future implementation, this study aimed to identify healthcare
Autor:
Jerome Sarris, Gerard Byrne, David Castle, Chad Bousman, Georgina Oliver, Lachlan Cribb, Scott Blair-West, Vlasios Brakoulias, David Camfield, Carolyn Ee, Suneel Chamoli, Mark Boschen, Olivia M. Dean, Nathan Dowling, Ranjit Menon, Jenifer Murphy, Najwa-Joelle Metri, Thomas P. Nguyen, Andrew Wong, Rebecca Jordan, Diana Karamacoska, Susan L. Rossell, Michael Berk, Chee H. Ng
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 117
Preliminary evidence has suggested that adjunctive N-acetylcysteine (NAC), an antioxidant precursor to glutathione, may reduce symptoms of obsessive-compulsive disorder (OCD). We conducted a 20-week, multi-site, randomized controlled trial to investi