Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Chad A. Malloff"'
Autor:
Robert G. Bristow, Theo van der Kwast, Igor Jurisica, Omer Ahmed, Alice Meng, Varune Rohan Ramnarine, Jenna Sykes, Melania Pintilie, Jeremy A. Squire, Wan L. Lam, Chad A. Malloff, Cherry L. Have, John Thoms, Michael Milosevic, Adrian S. Ishkanian, Gaetano Zafarana, Jennifer A. Locke
PDF file - 41K, Percentage genome alteration (PGA) levels are displayed for patient biopsies categorized as per their NKX3.1/T-category status (a), NKX3.1/PSA status (b), NKX3.1/Gleason-score status (c), NKX3.1/c-MYC/T-category status (d) and NKX3.1/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35d84b0dd25aadc18202def37b13754
https://doi.org/10.1158/1078-0432.22447703
https://doi.org/10.1158/1078-0432.22447703
Autor:
Robert G. Bristow, Theo van der Kwast, Igor Jurisica, Omer Ahmed, Alice Meng, Varune Rohan Ramnarine, Jenna Sykes, Melania Pintilie, Jeremy A. Squire, Wan L. Lam, Chad A. Malloff, Cherry L. Have, John Thoms, Michael Milosevic, Adrian S. Ishkanian, Gaetano Zafarana, Jennifer A. Locke
Supplementary Figure Legends 1-2, Tables 1-6 from NKX3.1 Haploinsufficiency Is Prognostic for Prostate Cancer Relapse following Surgery or Image-Guided Radiotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c741d5204d4fbb34561b1cd3346642ee
https://doi.org/10.1158/1078-0432.22447700.v1
https://doi.org/10.1158/1078-0432.22447700.v1
Autor:
Robert G. Bristow, Theo van der Kwast, Igor Jurisica, Omer Ahmed, Alice Meng, Varune Rohan Ramnarine, Jenna Sykes, Melania Pintilie, Jeremy A. Squire, Wan L. Lam, Chad A. Malloff, Cherry L. Have, John Thoms, Michael Milosevic, Adrian S. Ishkanian, Gaetano Zafarana, Jennifer A. Locke
Background: Despite the use of prostate specific antigen (PSA), Gleason-score, and T-category as prognostic factors, up to 40% of patients with intermediate-risk prostate cancer will fail radical prostatectomy or precision image-guided radiotherapy (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51550384b0bae2ce07e6be8270ed19cd
https://doi.org/10.1158/1078-0432.c.6521168.v1
https://doi.org/10.1158/1078-0432.c.6521168.v1
Autor:
William W Lockwood, Raj Chari, Bradley P Coe, Kelsie L Thu, Cathie Garnis, Chad A Malloff, Jennifer Campbell, Ariane C Williams, Dorothy Hwang, Chang-Qi Zhu, Timon P H Buys, John Yee, John C English, Calum Macaulay, Ming-Sound Tsao, Adi F Gazdar, John D Minna, Stephen Lam, Wan L Lam
Publikováno v:
PLoS Medicine, Vol 7, Iss 7, p e1000315 (2010)
Traditionally, non-small cell lung cancer is treated as a single disease entity in terms of systemic therapy. Emerging evidence suggests the major subtypes--adenocarcinoma (AC) and squamous cell carcinoma (SqCC)--respond differently to therapy. Ident
Externí odkaz:
https://doaj.org/article/f508a24cf83c448db07f726ff98ada8f
Autor:
Alice H Li, Simon J Waddell, Jason Hinds, Chad A Malloff, Manjeet Bains, Robert E Hancock, Wan L Lam, Philip D Butcher, Richard W Stokes
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11066 (2010)
H37Rv and H37Ra are well-described laboratory strains of Mycobacterium tuberculosis derived from the same parental strain, H37, that show dramatically different pathogenic phenotypes.In this study, the transcriptomes of the two strains during axenic
Externí odkaz:
https://doaj.org/article/780a64bf82654027a3fca32b503b54a2
Autor:
Theodorus van der Kwast, Xianyue Meng, Rosalind A. Eeles, David E. Neal, Jenna Sykes, Silvia Halim, Lauren C. Chong, Igor Jurisica, Lucia L. Lam, Alastair D. Lamb, Elai Davicioni, Denise Y.F. Mak, Wan L. Lam, Kenneth C. Chu, Helen Ross-Adams, Michael Milosevic, Nicholas Erho, John Thoms, Anne Y. Warren, Alejandro Berlin, Chad A. Malloff, Mark J Dunning, Emilie Lalonde, Honglei Xie, Melania Pintilie, CQ Yao, Cherry Have, Dorota H. Sendorek, Nicholas J. Harding, Robert G. Bristow, Michael Fraser, Christine P'ng, Jeremy A. Squire, Alan Dal Pra, Colin Cooper, Colin Collins, Michal R. Grzadkowski, Varune Rohan Ramnarine, Nathalie C. Moon, Gaetano Zafarana, Adrian Ishkanian, Paul C. Boutros
Publikováno v:
The Lancet Oncology. 15(13):1521-1532
Summary Background Clinical prognostic groupings for localised prostate cancers are imprecise, with 30–50% of patients recurring after image-guided radiotherapy or radical prostatectomy. We aimed to test combined genomic and microenvironmental indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0107946531f1f7f4fc6ee2ec369e5cab
Autor:
Omar Ahmed, Igor Jurisca, Robert G. Bristow, Jeremy A. Squire, Maisa Yoshimoto, Alice Meng, John Thoms, Jenna Sykes, Wan L. Lam, Michael Milosevic, Jennifer A. Locke, Melania Pintilie, Chad A. Malloff, Theo H. van der Kwast, Gaetano Zafarana, Adrian Ishkanian, Varune Rohan Ramnarine
Publikováno v:
Cancer. 118:4053-4062
Despite the use of PSA, Gleason score, and T-category as prognosticators in intermediate-risk prostate cancer, 20-40% of patients will fail local therapy. In order to optimize treatment approaches for intermediate-risk patients, additional genetic pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8540e16fb882446a04cf3f7ca2df29ac
https://doi.org/10.1002/cncr.26729
https://doi.org/10.1002/cncr.26729
Autor:
Theo H. van der Kwast, Gaetano Zafarana, Jenna Sykes, Jennifer A. Locke, Michael Milosevic, Omer Ahmed, Chad A. Malloff, Emma Tomlinson Guns, Varune Rohan Ramnarine, Wan L. Lam, Alice Meng, Igor Jurisica, Robert G. Bristow, Melania Pintilie
Publikováno v:
The Prostate. 72:1295-1305
BACKGROUND Androgen deprivation therapy (ADT) and novel agents targeting the androgen synthesis axis (e.g., abiraterone acetate) are adjuvant therapies that are currently, or may in the future be, combined with radiotherapy to reduce the chance of di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9cac1bdec86a498d7690e85b4663f65
https://doi.org/10.1002/pros.22478
https://doi.org/10.1002/pros.22478
Autor:
Kim M. Lonergan, Raj Chari, Bradley P. Coe, Cathie Garnis, Calum MacAulay, Chad A. Malloff, Carlos E. Alvarez, Stephen Lam, Wan L. Lam, Adi F. Gazdar, Kelsie L. Thu, Ian M. Wilson, William W. Lockwood
Publikováno v:
Cancer and Metastasis Reviews. 29:73-93
Advances in high-throughput, genome-wide profiling technologies have allowed for an unprecedented view of the cancer genome landscape. Specifically, high-density microarrays and sequencing-based strategies have been widely utilized to identify geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce011772f382c17c3f9745cf8f5c3ab8
https://doi.org/10.1007/s10555-010-9199-2
https://doi.org/10.1007/s10555-010-9199-2
Publikováno v:
Journal of Molecular Biology. 312:1-5
Horizontally transferred DNA is largely responsible for the dissemination of virulence traits amongst bacteria. Rapid identification of acquired DNA remains difficult as whole-genome sequencing of outbreak strains is impractical, and microarray-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3832ba3a969162dc52cac80ff85172f2
https://doi.org/10.1006/jmbi.2001.4925
https://doi.org/10.1006/jmbi.2001.4925