Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Chad A. Haraldson"'
Autor:
Kyle J. Lindstrom, Philip D. Heppner, Daniel J Willie, Michael E. Danielson, Charles M. Leir, Joshua R. Wurst, Gregory D. Lundquist, Sonja S. Mackey, Tushar A. Kshirsagar, Chad A. Haraldson, David S. Hays, Karl E. Benson
Publikováno v:
The Journal of Organic Chemistry. 72:4570-4573
The deprotonation and regioselective reaction of 2H-pyrazolo[3,4-c]quinolines with a variety of electrophiles is described. Electrophiles include benzaldehyde, DMF, carbon dioxide, and iodine. This method provides a direct route to a class of pharmac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0237f06064236349491db0ad2186ef
https://doi.org/10.1021/jo070392t
https://doi.org/10.1021/jo070392t
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:2357-2362
Two tricyclic analogs of artemisinin were designed based on a Comparative Molecular Field Analysis (CoMFA) model, and synthesized for antimalarial testing as part of a program to construct and validate modeling tools for drug design of novel antimala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::200069cae701be22ead10340d6440285
https://doi.org/10.1016/s0960-894x(97)00432-0
https://doi.org/10.1016/s0960-894x(97)00432-0