Epididymis Response Partly Compensates for Spermatozoa Oxidative Defects in snGPx4 and GPx5 Double Mutant Mice

Autor: Noblanc, Anaïs, Peltier, Manon, Damon-Soubeyrand, Christelle, Kerchkove, Nicolas, Chabory, Eléonore, Vernet, Patrick, Saez, Fabrice, Cadet, Rémi, Janny, Laurent, Pons-Rejraji, Hanae, Conrad, Marcus, Drevet, Joël, Kocer, Ayhan, Bishop, Alexander James Roy

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2012, 7 (6), pp.e38565. ⟨10.1371/journal.pone.0038565⟩
PLoS ONE, 2012, 7 (6), pp.e38565. ⟨10.1371/journal.pone.0038565⟩
PLoS ONE 7:e38565 (2012)
PLOS ONE 7(6), e38565 (2012). doi:10.1371/journal.pone.0038565
PLoS ONE, Vol 7, Iss 6, p e38565 (2012)

We report here that spermatozoa of mice lacking both the sperm nucleus glutathione peroxidase 4 (snGPx4) and the epididymal glutathione peroxidase 5 (GPx5) activities display sperm nucleus structural abnormalities including delayed and defective nucl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2680fb2aef4c23e568eb5b6f0e9ad344
https://hal.archives-ouvertes.fr/hal-02083321

Epididymis seleno-independent glutathione peroxidase 5 maintains sperm DNA integrity in mice.

Autor: Chabory, Eléonore¹, Damon, Christelle¹, Lenoir, Alain¹, Kauselmann, Gary², Kern, Hedrun², Zevnik, Branko², Garrel, Catherine³, Saez, Fabrice¹, Cadet, Rémi¹, Henry-Berger, Joelle¹, Schoor, Michael², Gottwald, Ulrich⁴, Habenicht, Ursula⁴, Drevet, Joël R.¹ joel.drevet@univ-bpclermont.fr, Vernet, Patrick¹, Chabory, Eléonore⁵ (AUTHOR), Cadet, Rémi (AUTHOR), Drevet, Joël R (AUTHOR)

Publikováno v: Journal of Clinical Investigation. Jul2009, Vol. 119 Issue 7, p2074-2085. 12p. 3 Color Photographs, 3 Black and White Photographs, 1 Diagram, 1 Chart, 7 Graphs.

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