Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Chabane Tibiche"'
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 15, Iss 2, Pp 121-129 (2017)
Mutated genes are rarely common even in the same pathological type between cancer patients and as such, it has been very challenging to interpret genome sequencing data and difficult to predict clinical outcomes. PIK3CA is one of a few genes whose mu
Externí odkaz:
https://doaj.org/article/a4c802a5437c4827af1e839df7b0bc7f
Autor:
Naif Zaman, Lei Li, Maria Luz Jaramillo, Zhanpeng Sun, Chabane Tibiche, Myriam Banville, Catherine Collins, Mark Trifiro, Miltiadis Paliouras, Andre Nantel, Maureen O’Connor-McCourt, Edwin Wang
Publikováno v:
Cell Reports, Vol 5, Iss 1, Pp 216-223 (2013)
Individual cancer cells carry a bewildering number of distinct genomic alterations (e.g., copy number variations and mutations), making it a challenge to uncover genomic-driven mechanisms governing tumorigenesis. Here, we performed exome sequencing o
Externí odkaz:
https://doaj.org/article/c5734c4ca3ab46809467df3d61abd8ef
Publikováno v:
Genomics, Proteomics & Bioinformatics
Genomics, Proteomics & Bioinformatics, Vol 15, Iss 2, Pp 121-129 (2017)
Genomics, Proteomics & Bioinformatics, Vol 15, Iss 2, Pp 121-129 (2017)
Mutated genes are rarely common even in the same pathological type between cancer patients and as such, it has been very challenging to interpret genome sequencing data and difficult to predict clinical outcomes. PIK3CA is one of a few genes whose mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6567074ffc7dde2bde1ee3ac021384
https://doi.org/10.1016/j.gpb.2017.02.002
https://doi.org/10.1016/j.gpb.2017.02.002
Germline variants associated with leukocyte genes predict tumor recurrence in breast cancer patients
Autor:
Jean-Sébastien Milanese, Richard Marcotte, Zhigang Meng, Chabane Tibiche, Edwin Wang, Simon Drouin, Jinfeng Zou, André Nantel
Publikováno v:
NPJ Precision Oncology
npj Precision Oncology, Vol 3, Iss 1, Pp 1-9 (2019)
npj Precision Oncology, Vol 3, Iss 1, Pp 1-9 (2019)
Germline variants such as BRCA1/2 play an important role in tumorigenesis and clinical outcomes of cancer patients. However, only a small fraction (i.e., 5–10%) of inherited variants has been associated with clinical outcomes (e.g., BRCA1/2, APC, T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cab35c5fa4db5ebc9d830862d1ff38ce
https://doi.org/10.1038/s41698-019-0100-7
https://doi.org/10.1038/s41698-019-0100-7
Autor:
André Nantel, Pengyong Han, Edwin Wang, Jean-Sébastien Milanese, Chabane Tibiche, Jinfeng Zou, Naif Zaman, Arnaud Droit, Zhigang Meng
Germline genetic variants such as BRCA1/2 could play an important role in tumorigenesis and even clinical outcomes of cancer patients. These germline mutations have been used for genetic counselling and testing to establish as a standard-of-care proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56aa7dc7b8a84a2951607b7d32f51197
https://doi.org/10.1101/312355
https://doi.org/10.1101/312355
Autor:
Jean-Sébastien Milanese, Pengyong Han, Zhigang Meng, Jinfeng Zou, André Nantel, Edwin Wang, Chabane Tibiche, Naif Zaman, Arnaud Droit
Continual reduction in sequencing cost is expanding the accessibility of genome sequencing data for routine clinical applications. However, the lack of methods to construct machine learning-based predictive models using these datasets has become a cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584f567f1e4ee76c5c1e89277072ba11
Autor:
Maria L. Jaramillo, Lei Li, Zhanpeng Sun, Chabane Tibiche, Miltiadis Paliouras, Edwin Wang, André Nantel, Maureen D. O'Connor-McCourt, Mark Trifiro, Naif Zaman, Catherine Collins, Myriam Banville
Publikováno v:
Cell Reports, Vol 5, Iss 1, Pp 216-223 (2013)
Individual cancer cells carry a bewildering number of distinct genomic alterations i.e., copy number variations and mutations, making it a challenge to uncover genomic-driven mechanisms governing tumorigenesis. Here we performed exome-sequencing on s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6201c182f99953a6cf94a82d7e7dcc05
Autor:
Jinfeng Zou, Maureen D. O'Connor-McCourt, Mark Trifiro, Chabane Tibiche, Naif Zaman, Shanwu Gao, Edwin Wang
Importance Decisions regarding adjuvant therapy in patients with stage II colorectal cancer (CRC) have been among the most challenging and controversial in oncology over the past 20 years. Objective To develop robust combinatory cancer hallmark–bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c41c11377b4005e74b3b4c587cc2e34
https://nrc-publications.canada.ca/eng/view/object/?id=e8223e68-3797-4ba5-9952-6894d04b7fa6
https://nrc-publications.canada.ca/eng/view/object/?id=e8223e68-3797-4ba5-9952-6894d04b7fa6
Autor:
Daoquan Xiang, Eddy Risseeuw, Wilf Keller, Edwin Wang, Gopalan Selvaraj, Prakash Venglat, Yongguo Cao, Vivijan Babic, Hui Yang, Raju Datla, Chabane Tibiche, Mathieu Cloutier
Publikováno v:
Plant Physiology. 156:346-356
Embryogenesis is central to the life cycle of most plant species. Despite its importance, because of the difficulty associated with embryo isolation, global gene expression programs involved in plant embryogenesis, especially the early events followi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540c3628006413844f110de882a4c9b4
https://doi.org/10.1104/pp.110.171702
https://doi.org/10.1104/pp.110.171702
Autor:
Chabane Tibiche, Edwin Wang
Publikováno v:
The Open Systems Biology Journal. 1:1-8
MicroRNA (miRNA) is an emerging class of non-coding small RNAs, which post-transcriptionally regulate a large number of genes and become important regulators of a broad spectrum of biological processes. To understand the principles of miRNA regulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d55f9c62af7d58c3b77a5904673e6b
https://doi.org/10.2174/1876392800801010001
https://doi.org/10.2174/1876392800801010001