Zobrazeno 1 - 10
of 241
pro vyhledávání: '"ChIP, Chromatin immunoprecipitation"'
Publikováno v:
Regenerative Therapy
Regenerative Therapy, Vol 18, Iss, Pp 430-440 (2021)
Regenerative Therapy, Vol 18, Iss, Pp 430-440 (2021)
Background Circular RNAs (circRNAs) are non-coding RNAs that play a pivotal role in bone diseases. RUNX3 was an essential transcriptional regulator during osteogenesis. However, it is unknown whether RUNX3 regulates hsa_circ_0005752 during osteogenic
Publikováno v:
Cell Cycle
Binding sites of the chromatin regulator protein CTCF function as important landmarks in the human genome. The recently characterized CTCF-binding sites at LINE-1 repeats depend on another repeat-regulatory protein CGGBP1. These CGGBP1-dependent CTCF
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2880-2899 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2880-2899 (2021)
Aberrant activation of NLRP3 inflammasome in colonic macrophages strongly associates with the occurrence and progression of ulcerative colitis. Although targeting NLRP3 inflammasome has been considered to be a potential therapy, the underlying mechan
Autor:
Gregory Tiao, Talita Ferreira Margues Aguiar, Alexander Bondoc, Soona Shin, Maria Prates Rivas, Michael E. Johnston, Ruhi Gulati, Meenasri Kumbaji, Ana Cristina Victorino Krepischi, James I. Geller, Lubov Timchenko, Nikolai Timchenko
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1669-1682 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1669-1682 (2021)
Background & Aims Epigenetic regulation of gene expression plays a critical role in the development of liver cancer; however, the molecular mechanisms of epigenetic-driven liver cancers are not well understood. The aims of this study were to examine
Autor:
Yulong He, Jianbo Xu, Peng Shi, Xinde Ou, Wen Zhou, Shirong Cai, Jin Li, Yujie Yuan, Jianjun Peng, Taiqiang Su, Liangliang Lin, Qinbo Cai
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 857-880 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The association between cellular senescence and Helicobacter pylori–induced atrophic gastritis is not clear. Here, we explore the role of cellular senescence in H pylori–induced atrophic gastritis and the underlying mechanism. M
Autor:
Oliver G. McDonald, M. Kay Washington, Fang Yan, Yilin Deng, Anna L. Means, D. Brent Polk, Sari Acra, Richard M. Peek
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1327-1345 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Colonization by gut microbiota in early life confers beneficial effects on immunity throughout the host’s lifespan. We sought to elucidate the mechanisms whereby neonatal supplementation with p40, a probiotic functional factor, re
Autor:
Rui Xie, Jingyu Xu, Yong-sheng Teng, Chuan-jie Hao, Shi-Ming Yang, Weisan Chen, Tao Liu, Yi-pin Lv, Yuan Zhuang, Quanming Zou, Fang-yuan Mao, Ping Cheng, Yu-gang Liu
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 395-425 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Rev-erbα represents a powerful transcriptional repressor involved in immunity. However, the regulation, function, and clinical relevance of Rev-erbα in Helicobacter pylori infection are presently unknown. Methods Rev-erbα was exa
Autor:
Maya Finkel, Nufar Buchshtab, Meirav Bar-Shimon, Noga Korenfeld, Ido Goldstein, Meital Charni-Natan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 1021-1036 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Gluconeogenesis from amino acids (AAs) maintains glucose homeostasis during fasting. Although glucagon is known to regulate AA catabolism, the contribution of other hormones to it and the scope of transcriptional regulation dictatin
Autor:
Chang Hwa Jung, Hyunjung Lee, Hyo-Deok Seo, Jiyun Ahn, Young In Kim, Tae-Youl Ha, Seung Yeon Ha
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1201-1213 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The development of nonalcoholic fatty liver disease (NAFLD) can be modulated by microRNAs (miRNA). Dietary polyphenols modulate the expression of miRNA such as miR-467b-3p in the liver. In addition, 6-gingerol (6-G), the functional
Publikováno v:
Journal of Advanced Research, Vol 26, Iss, Pp 123-135 (2020)
Journal of Advanced Research
Journal of Advanced Research
Graphical abstract The map illustrating mechanisms associated with lncRNA HIF1A-AS2-mediated inflammation in the atherosclerosis. LncRNA HIF1A-AS2 forms a complex with USF1, which is recruited into the ATF2 promoter to elevate ATF2 expression, thus p